Response of recombinant calcineurin to metal ions, reduction-oxidation agents, and enzymatic modification

scientific article published in November 2002

Response of recombinant calcineurin to metal ions, reduction-oxidation agents, and enzymatic modification is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1046-5928(02)00520-X
P698PubMed publication ID12406672

P2093author name stringBruce L Martin
Donna J Spannaus-Martin
Cheryl Bartleson
David J Rhode
Jennifer Imparl-Radosevich
P2860cites workCrystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complexQ24310797
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X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complexQ27729433
Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structuresQ27733138
Calcineurin: form and functionQ27934527
Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitroQ40887915
Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domainQ42067056
Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active siteQ43821732
Activation of calcineurin by the trivalent metal terbiumQ48405630
Activation of brain calcineurin towards proteins containing Thr(P) and Ser(P) by Ca2+, calmodulin, Mg2+ and transition metal ionsQ48602909
Spectroscopic and enzymatic characterization of the active site dinuclear metal center of calcineurin: implications for a mechanistic roleQ48630674
Intrinsic phosphatase activity of bovine brain calcineurin requires a tightly bound trace metalQ48681891
20 Use of calmodulin affinity chromatography for purification of specific calmodulin-dependent enzymesQ48842361
Superoxide dismutase protects calcineurin from inactivationQ48892622
Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changesQ48958065
Ca2+-induced hydrophobic site on calmodulin: application for purification of calmodulin by phenyl-Sepharose affinity chromatographyQ49015574
The protein phosphatases involved in cellular regulation. 5. Purification and properties of a Ca2+/calmodulin-dependent protein phosphatase (2B) from rabbit skeletal muscle.Q50928896
Comparison of the reaction progress of calcineurin with Mn2+ and Mg2+.Q51091458
Isotope effect studies on the calcineurin phosphoryl-transfer reaction: transition state structure and effect of calmodulin and Mn2+.Q51101320
Characterization of Calcineurin in Human NeutrophilsQ61881303
Specificity and mode of action of the muscle-type protein-arginine deiminaseQ67513932
Affinity chromatography of peptidylarginine deiminase from rabbit skeletal muscle on a column of soybean trypsin inhibitor (Kunitz)-SepharoseQ69517135
Activation of calcineurin by nickel ionsQ70162566
Studies of calcineurin-calmodulin interaction: probing the role of arginine residues using peptidylarginine deiminaseQ72200047
Crystal structure of a purple acid phosphatase containing a dinuclear Fe(III)-Zn(II) active siteQ72287448
Dephosphorylation of protein kinase C substrates, neurogranin, neuromodulin, and MARCKS, by calcineurin and protein phosphatases 1 and 2AQ72565963
Acidic residues are involved in substrate recognition by two soluble protein tyrosine phosphatases, PTP-5 and rrbPTP-1Q72609567
Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80)Q72926181
Redox regulation of calcineurin in T-lymphocytesQ73154583
Inactivation of calcineurin by hydrogen peroxide and phenylarsine oxide. Evidence for a dithiol-disulfide equilibrium and implications for redox regulationQ73486317
Selective activation of calcineurin by dipicolinic acidQ73728065
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutaseQ74016060
Differences between Mg(2+) and transition metal ions in the activation of calcineurinQ74016446
Effect of substitution inert metal complexes on calcineurinQ77767361
P433issue2
P304page(s)194-201
P577publication date2002-11-01
P1433published inProtein Expression and PurificationQ7251430
P1476titleResponse of recombinant calcineurin to metal ions, reduction-oxidation agents, and enzymatic modification
P478volume26