Design and synthesis of novel imidazole derivatives as potent inhibitors of allene oxide synthase(CYP74).

scientific article published in December 2002

Design and synthesis of novel imidazole derivatives as potent inhibitors of allene oxide synthase(CYP74). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0968-0896(02)00422-4
P698PubMed publication ID12413826

P2093author name stringNoboru Murofushi
Keimei Oh
P2860cites workThe Arabidopsis male-sterile mutant, opr3, lacks the 12-oxophytodienoic acid reductase required for jasmonate synthesisQ28145405
BIOSYNTHESIS AND ACTION OF JASMONATES IN PLANTSQ28249530
Structure-activity relationships of a new antifungal imidazole, AFK-108, and related compoundsQ28372609
Reactivity of lysine moieties toward an epoxyhydroxylinoleic acid derivative: aminolysis versus hydrolysisQ30583889
Plant defense in the absence of jasmonic acid: the role of cyclopentenones.Q33948155
Distinct roles for jasmonate synthesis and action in the systemic wound response of tomatoQ34029515
Jasmonic acid distribution and action in plants: regulation during development and response to biotic and abiotic stressQ34305623
Jasmonate-related mutants of Arabidopsis as tools for studying stress signalingQ34582634
Cloning, molecular and functional characterization of Arabidopsis thaliana allene oxide synthase (CYP 74), the first enzyme of the octadecanoid pathway to jasmonatesQ38358208
Inhibitors of Cytochrome P-450s and their mechanism of actionQ40317968
Purification of an allene oxide synthase and identification of the enzyme as a cytochrome P-450.Q43986032
Steric factors in the inhibitory interaction of imidazoles with microsomal enzymesQ45082457
Aspirin inhibition and acetylation of the plant cytochrome P450, allene oxide synthase, resembles that of animal prostaglandin endoperoxide H synthaseQ48036494
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9Q71904700
Allene oxide synthase: a major control point in Arabidopsis thaliana octadecanoid signallingQ77432752
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3707-3711
P577publication date2002-12-01
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleDesign and synthesis of novel imidazole derivatives as potent inhibitors of allene oxide synthase(CYP74).
P478volume10

Reverse relations

cites work (P2860)
Q57715433Binding of Imidazole Stabilizes Low-spin State of Heme Iron in Dual-Substrate-Specific Rice Allene Oxide Synthase-1
Q34049402Dual positional substrate specificity of rice allene oxide synthase-1: insight into mechanism of inhibition by type II ligand imidazole
Q64944244Synthesis of 2RS,4RS-1-[2-phenyl-4-[2-(2-trifluromethoxy-phenoxy)-ethyl]-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole derivatives as potent inhibitors of brassinosteroid biosynthesis.
Q46660428The allene oxide cyclase family of Arabidopsis thaliana: localization and cyclization
Q30159578The crystal structure of Arabidopsis thaliana allene oxide cyclase: insights into the oxylipin cyclization reaction

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