Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus

scientific article published on 17 July 2009

Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00124.2009
P698PubMed publication ID19617408

P2093author name stringYoshifusa Aizawa
Kenichi Watanabe
Makoto Kodama
Meilei Ma
Rajarajan A Thandavarayan
Anthony J Muslin
Narasimman Gurusamy
Punniyakoti T Veeraveedu
Tetsuya Konishi
Shaosong Zhang
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The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathyQ28510616
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsQ29615216
The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosisQ34183974
Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarctionQ34408669
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expressionQ34440843
Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoformsQ34483654
Oxidative stress and diabetic cardiomyopathy: a brief reviewQ34817248
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Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidaseQ35949648
Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.Q39802111
p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).Q40533259
Possible involvement of heat shock protein 25 in the angiotensin II-induced glomerular mesangial cell contraction via p38 MAP kinaseQ40922000
Growth factors and mitogen-activated protein kinasesQ41695587
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cellsQ43618959
Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heartQ43670109
Chronic exposure of human mesangial cells to high glucose environments activates the p38 MAPK pathwayQ43725703
Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidaseQ43819761
Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblastsQ44087065
Activation of NADPH oxidase during progression of cardiac hypertrophy to failureQ44167921
Mitogen-activated protein kinases in the acute diabetic myocardiumQ44573882
Salt Intake, Oxidative Stress, and Renal Expression of NADPH Oxidase and Superoxide DismutaseQ44625393
The effects of iron dextran on the oxidative stress in cardiovascular tissues of rats with chronic renal failureQ44846324
Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathyQ44962642
Dominant negative 14-3-3 promotes cardiomyocyte apoptosis in early stage of type I diabetes mellitus through activation of JNK.Q44968307
Inactivation of 14-3-3 protein exacerbates cardiac hypertrophy and fibrosis through enhanced expression of protein kinase C beta 2 in experimental diabetesQ46523244
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.Q46579574
MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in ratsQ46650368
14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathyQ46701049
Glycogen synthase kinase 3beta together with 14-3-3 protein regulates diabetic cardiomyopathy: effect of losartan and tempolQ46985474
p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophyQ48010552
High glucose activates rat pancreatic stellate cells through protein kinase C and p38 mitogen-activated protein kinase pathway.Q50699736
Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus.Q50723411
Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study.Q53751216
p38 MAP Kinase Mediates Inflammatory Cytokine Induction in Cardiomyocytes and Extracellular Matrix Remodeling in HeartQ58198525
P433issue3
P304page(s)H911-9
P577publication date2009-07-17
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleDominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus
P478volume297

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cites work (P2860)
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