| scholarly article | Q13442814 |
| P50 | author | Senena Corbalan | Q58323361 |
| Juan C. Gómez-Fernández | Q61144209 | ||
| P2093 | author name string | Stephen R Bolsover | |
| P2860 | cites work | The extended protein kinase C superfamily | Q24530820 |
| Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? | Q26269956 | ||
| Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine | Q27620399 | ||
| SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling | Q27860614 | ||
| Synaptotagmin I functions as a calcium regulator of release probability | Q28204147 | ||
| C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity | Q28360864 | ||
| C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state | Q28613889 | ||
| Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals | Q28631532 | ||
| Electrostatic control of the membrane targeting of C2 domains | Q34110570 | ||
| Membrane targeting by C1 and C2 domains | Q34296902 | ||
| Protein kinase C inhibitors | Q34457430 | ||
| Interplay between calcium, diacylglycerol, and phosphorylation in the spatial and temporal regulation of PKCalpha-GFP. | Q40733408 | ||
| Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization. | Q40769171 | ||
| Studies of signal transduction events using chimeras to green fluorescent protein | Q40846784 | ||
| Membrane targeting and cytoplasmic sequestration in the spatiotemporal localization of human protein kinase C alpha. | Q40899308 | ||
| Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues | Q41028602 | ||
| Calcium signalling: sphingosine kinase versus phospholipase C? | Q41110730 | ||
| Circular dichroism analysis of ligand-induced conformational changes in protein kinase C. Mechanism of translocation of the enzyme from the cytosol to the membranes and its implications | Q41877332 | ||
| A structure-function study of the C2 domain of cytosolic phospholipase A2. Identification of essential calcium ligands and hydrophobic membrane binding residues. | Q42058981 | ||
| Regulation of protein kinase C betaII by its C2 domain | Q42061325 | ||
| Simultaneous visualization of the translocation of protein kinase Calpha-green fluorescent protein hybrids and intracellular calcium concentrations. | Q42159022 | ||
| Roles of calcium ions in the membrane binding of C2 domains. | Q43000381 | ||
| Ca2+ differentially regulates conventional protein kinase Cs' membrane interaction and activation | Q43412929 | ||
| Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain | Q43782188 | ||
| Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein module | Q43909644 | ||
| Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha. | Q44038198 | ||
| Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules | Q46419582 | ||
| Circular dichroic studies of protein kinase C and its interactions with calcium and lipid vesicles | Q48529066 | ||
| Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers. | Q50524047 | ||
| Protein kinase C interaction with calcium: a phospholipid-dependent process | Q68649114 | ||
| The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane | Q73039506 | ||
| Protein kinase calpha targeting is regulated by temporal and spatial changes in intracellular free calcium concentration [Ca(2+)](i) | Q74121605 | ||
| Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I | Q77216937 | ||
| Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy | Q77332922 | ||
| Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation | Q77955215 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10282-10290 | |
| P577 | publication date | 2003-01-13 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane | |
| P478 | volume | 278 |
| Q44739150 | A critical intramolecular interaction for protein kinase Cepsilon translocation |
| Q24319097 | Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation |
| Q93063920 | An electrostatic switching mechanism to control the lipid transfer activity of Osh6p |
| Q36854412 | Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity |
| Q38783144 | Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate. |
| Q37418857 | Configuration of PKCalpha-C2 domain bound to mixed SOPC/SOPS lipid monolayers |
| Q38268439 | Differential targeting of cPKC and nPKC decodes and regulates Ca²⁺ and lipid signalling |
| Q28251494 | Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells |
| Q36910176 | Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα. |
| Q40098611 | Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol |
| Q48051420 | Investigation of the Effect of Bilayer Composition on PKCα-C2 Domain Docking Using Molecular Dynamics Simulations. |
| Q48313983 | Kisspeptin-evoked calcium signals in isolated primary rat gonadotropin- releasing hormone neurones. |
| Q33961419 | Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity |
| Q49946480 | Notes and tips for improving quality of lipid-protein overlay assays |
| Q30480459 | PKCalpha: a versatile key for decoding the cellular calcium toolkit |
| Q34852542 | Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity. |
| Q35157028 | Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα |
| Q37882868 | Protein kinase C: the "masters" of calcium and lipid |
| Q35558433 | Specific localization and timing in neuronal signal transduction mediated by protein-lipid interactions. |
| Q34298292 | Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain |
| Q27654558 | Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2 |
| Q27652618 | Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A |
| Q27680751 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1 |
| Q39004144 | Targeted activation of conventional and novel protein kinases C through differential translocation patterns |
| Q28571511 | The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells |
| Q35606778 | The cPLA2 C2alpha domain in solution: structure and dynamics of its Ca2+-activated and cation-free states |
| Q30499501 | The calcium binding loops of the cytosolic phospholipase A2 C2 domain specify targeting to Golgi and ER in live cells |
| Q40555297 | The cytosolic II-III loop of Cav2.3 provides an essential determinant for the phorbol ester-mediated stimulation of E-type Ca2+ channel activity. |
| Q40286905 | The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells |
| Q35734162 | Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα. |
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