Mitochondrially mediated synergistic cell killing by bile acids.

scientific article published in January 2003

Mitochondrially mediated synergistic cell killing by bile acids. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0925-4439(02)00224-7
P698PubMed publication ID12527417
P5875ResearchGate publication ID10951791

P50authorCarlos M. PalmeiraQ47503993
Anabela Pinto RoloQ51064473
P2093author name stringKendall B Wallace
P2860cites workInduction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteasesQ77136049
The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondriaQ77313291
Ursodeoxycholic acid in cholestasis: potential mechanisms of action and therapeutic applicationsQ77598543
A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study GroupQ28243457
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagyQ28280478
Chapter 4 Preparation of Isolated Rat Liver CellsQ29616604
URSO-panacea or placebo?Q33873354
Mitochondrial targets of drug toxicityQ33932157
Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calciumQ34109467
Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyesQ34260290
Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytesQ35824326
Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosisQ36235778
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbationQ37383640
The mitochondrial permeability transition.Q40462729
Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids.Q41341706
Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acidsQ41668171
Effects of bile salts on the plasma membranes of isolated rat hepatocytesQ41900837
Effects of ursodeoxycholic acid and chenodeoxycholic acid on human hepatocytes in primary cultureQ42276877
Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.Q43868844
Reduction of hepatocarcinogenesis by ursodeoxycholic acid in ratsQ43997238
Antioxidant defenses in the bile duct-ligated ratQ46424638
Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes.Q51624442
Protection by acidotic pH and fructose against lethal injury to rat hepatocytes from mitochondrial inhibitors, ionophores and oxidant chemicals.Q52484678
Prognostic factors and long-term effects of ursodeoxycholic acid on liver biochemical parameters in patients with primary biliary cirrhosisQ58376775
Bile Acids Affect Liver Mitochondrial Bioenergetics: Possible Relevance for Cholestasis TherapyQ60398074
Bile acid concentrations in human and rat liver tissue and in hepatocyte nucleiQ60895762
Improved ion-pair high-performance liquid chromatographic method for the quantification of a wide variety of nucleotides and sugar-nucleotides in animal cellsQ67868807
Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosisQ68134833
Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trialQ69357047
Determination of pyridine dinucleotides in cell extracts by high-performance liquid chromatographyQ70976314
Hepatic levels of bile acids in end-stage chronic cholestatic liver diseaseQ71665237
A rapid beta-NADH-linked fluorescence assay for lactate dehydrogenase in cellular deathQ71690129
Ursodeoxycholate protects oxidative mitochondrial metabolism from bile acid toxicity: dose-response study in isolated rat liver mitochondriaQ72862935
Glutathione status of isolated rat hepatocytes affects bile acid-induced cellular necrosis but not apoptosisQ73598613
P433issue1
P1104number of pages6
P304page(s)127-132
P577publication date2003-01-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleMitochondrially mediated synergistic cell killing by bile acids
P478volume1637

Reverse relations

cites work (P2860)
Q42709815A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development
Q58579858Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome
Q58560352Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
Q38059807Anticancer steroids: linking natural and semi-synthetic compounds
Q36006541Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis
Q39657434Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development
Q36972843NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice
Q37309043Role of glucuronidation for hepatic detoxification and urinary elimination of toxic bile acids during biliary obstruction
Q34272924SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
Q24627930SRT1720 improves survival and healthspan of obese mice
Q57115299Serum Metabonomics Analysis of Liver Failure Treated by Nonbioartificial Liver Support Systems
Q39896739Toxicity of peroxisomal C27-bile acid intermediates
Q44314505Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.

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