Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells

scientific article published on 13 November 2013

Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.201343617
P698PubMed publication ID24122358

P50authorFelice RivelleseQ90465512
Jeroen N StoopQ114258754
Aleida M BakkerQ114563700
Rene E ToesQ42494390
Jolien SuurmondQ60328856
Tom HuizingaQ77086497
P2860cites workBasophils function as antigen-presenting cells for an allergen-induced T helper type 2 responseQ24613860
A mechanism for the initiation of allergen-induced T helper type 2 responsesQ34010133
CD11c depletion severely disrupts Th2 induction and development in vivoQ34161501
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cellsQ77357447
Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responsesQ77995910
Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1Q83088516
Expression and function of toll-like receptors in human basophilsQ83987345
Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergenQ34161524
The immunoglobulin E-Toll-like receptor networkQ34996802
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.Q35132544
Genetic analysis of basophil function in vivo.Q35731933
FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cellsQ35849299
Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulationQ36361406
How are T(H)2-type immune responses initiated and amplified?Q36394985
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasiteQ36399604
Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease.Q36711467
Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 productionQ36861095
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.Q37263947
Etiology of asthma exacerbations.Q37327669
The danger within: endogenous danger signals, atopy and asthmaQ37328368
Nonredundant roles of basophils in immunity.Q37821923
Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.Q39444927
Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3.Q39901791
Cutting edge: IPSE/alpha-1, a glycoprotein from Schistosoma mansoni eggs, induces IgE-dependent, antigen-independent IL-4 production by murine basophils in vivoQ40137966
Requirement for IL-13 independently of IL-4 in experimental asthmaQ41881960
Alarming dendritic cells for Th2 inductionQ41953596
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigensQ42261747
Basophils are not the key antigen-presenting cells in allergic patientsQ42591766
Toll-like receptor activation in basophils contributes to the development of IgG4-related diseaseQ44200305
Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.Q44268237
Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mitesQ44276703
Parasite antigen-driven basophils are a major source of IL-4 in human filarial infectionsQ44757017
Toll-like receptor 2 ligands activate human basophils for both IgE-dependent and IgE-independent secretionQ45254351
Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humansQ45892577
An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptorQ46305097
Lack of protease activated receptor (PAR) expression in purified human basophils.Q46521308
Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.Q47734042
Inflammatory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4.Q50758071
Disruption of the murine IL-4 gene blocks Th2 cytokine responses.Q52516840
The role of high-mobility group box-1 (HMGB1) in the pathogenesis of asthma.Q53364206
Severity of asthma is related to endotoxin in house dustQ71906927
P433issue2
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)386-396
P577publication date2013-11-13
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleActivation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells
P478volume44

Reverse relations

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