Effects of U-69,593, a kappa-opioid receptor agonist, on carrageenin-induced peripheral oedema and Fos expression in the rat spinal cord

scientific article published in April 1999

Effects of U-69,593, a kappa-opioid receptor agonist, on carrageenin-induced peripheral oedema and Fos expression in the rat spinal cord is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-2999(99)00153-3
P698PubMed publication ID10334505

P2093author name stringJ M Besson
G Catheline
S Le Guen
P2860cites workFunctional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the ratQ24685654
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) proceduresQ26778382
Novel developments with selective, non-peptidic kappa-opioid receptor agonistsQ28259198
Psychotomimesis mediated by kappa opiate receptorsQ28287612
Kappa- and delta-opioids block sympathetically dependent hyperalgesiaQ28335267
Ethical guidelines for investigations of experimental pain in conscious animalsQ29617510
Effect of the peripherally selective kappa-opioid agonist, asimadoline, on adjuvant arthritisQ35027644
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissueQ35221862
The site of anti-arthritic action of the kappa-opioid, U-50, 488H, in adjuvant arthritis: importance of local administrationQ35874021
Central and peripheral actions of the novel kappa-opioid receptor agonist, EMD 60400Q35874371
Kappa-opioid receptors and analgesiaQ37874600
Selective blockade of peripheral delta opioid agonist induced antinociception by intrathecal administration of delta receptor antisense oligodeoxynucleotide.Q38350445
Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiationQ39401533
Effects of spinal kappa-opioid receptor agonists on the responsiveness of nociceptive superficial dorsal horn neurons.Q41134399
Pharmacology and mechanisms of opioid analgesic activityQ41374982
kappa-Opioid agonists produce antinociception after i.v. and i.c.v. but not intrathecal administration in the rat.Q41775466
Distinct antinociceptive actions mediated by different opioid receptors in the region of lamina I and laminae III-V of the dorsal horn of the rat.Q41883863
Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn neuronesQ41962723
Spinal antinociceptive actions and naloxone reversibility of intravenous mu- and kappa-opioids in spinalized rats: potency mismatch with values reported for spinal administrationQ42207036
Spinal antinociceptive actions of mu- and kappa-opioids: the importance of stimulus intensity in determining 'selectivity' between reflexes to different modalities of noxious stimulusQ42847477
Peripheral and spinal actions of opioids in the blockade of the autonomic response evoked by compression of the inflamed knee jointQ43664117
Morphine inhibits the carrageenan-induced oedema and the chemoluminescence of leucocytes stimulated by zymosanQ44138142
Differential effects of opioid receptor agonists on nociception and cAMP level in the spinal cord of monoarthritic ratsQ44332390
kappa-opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cordQ44332405
Antinociceptive effect of a kappa-opioid receptor agonist that minimally crosses the blood-brain barrier (ICI 204448) in a rat model of mononeuropathyQ44332648
Peripheral opioid modulation of pain and inflammation in the formalin testQ44333931
Pharmacological evidence for the involvement of the endogenous opioid system in the response to local inflammation in the rat paw.Q44334733
Stimulus intensity and the comparative efficacy of mu- and kappa-opioid agonists on nociceptive spinal reflexes in the rat.Q44336002
Peripheral kappa-opioid modulation of the formalin response: an electrophysiological study in the rat.Q44336588
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cordQ44338465
Mu- and kappa-opioid receptor agonists produce peripheral inhibition of neurogenic plasma extravasation in rat skinQ44340134
Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic painQ44340306
Antinociceptive effects of mu- and kappa-agonists in inflammation are enhanced by a peripheral opioid receptor-specific mechanismQ44343710
Peripheral kappa 1-opioid receptor-mediated analgesia in miceQ44343737
The influence of opioid receptor subtypes on the processing of nociceptive inputs in the spinal dorsal horn of the cat.Q44343866
Effect of mu, delta and kappa opioid receptor agonists on a reactive oxygen species mediated model of skin inflammationQ44343940
The antinociceptive activity of kappa- but not delta-opioid receptor agonists is maintained in morphine-tolerant neuropathic ratsQ44344855
Peripheral component in the enhanced antinociceptive effect of systemic U-69,593, a kappa-opioid receptor agonist in mononeuropathic ratsQ44350417
Effects of opioid receptor antagonists on the effects of i.v. morphine on carrageenin evoked c-Fos expression in the superficial dorsal horn of the rat spinal cordQ44351652
Standardization of the rat paw formalin test for the evaluation of analgesicsQ46781531
Involvement of the spinoparabrachial pathway in inflammatory nociceptive processes: a c-Fos protein study in the awake rat.Q47814949
Actions of opioids on primate spinothalamic tract neuronsQ48308407
c-fos Expression in rat lumbar spinal cord during the development of adjuvant-induced arthritisQ48471048
Morphine or U-50,488 suppresses Fos protein-like immunoreactivity in the spinal cord and nucleus tractus solitarii evoked by a noxious visceral stimulus in the ratQ48549928
The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord.Q50919908
Antinociceptive effects of dynorphin peptides in a model of inflammatory pain.Q54212754
Concomitant Administration of Morphine and an N-Methyl-D-Aspartate Receptor Antagonist Profoundly Reduces Inflammatory Evoked Spinal c-Fos ExpressionQ60679680
When is the maximal effect of pre-administered systemic morphine on carrageenin evoked spinal c-Fos expression in the rat?Q60679684
Cholecystokinin B receptor antagonism enhances the ability of a low dose of morphine to reduce c-Fos expression in the spinal cord of the ratQ60679687
Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammationQ67465026
Spinal antinociceptive synergy between clonidine and morphine, U69593, and DPDPE: isobolographic analysisQ68619247
Opiates suppress carrageenan-induced edema and hyperthermia at doses that inhibit hyperalgesiaQ68660880
Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the catQ69900220
Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin testQ69928787
The analgesic drug buprenorphine inhibits osteoclastic bone resorption in vitro, but is proinflammatory in rat adjuvant arthritisQ71549315
Involvement of beta-endorphin in the modulation of paw inflammatory edema in the ratQ71606185
Opiate agonists inhibit neurogenic plasma extravasation in the ratQ72654042
Receptor localization in the mammalian dorsal horn and primary afferent neuronsQ73535647
Dose-related anti-inflammatory/analgesic effects of lornoxicam: a spinal c-Fos protein study in the ratQ74293339
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)287-296
P577publication date1999-04-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleEffects of U-69,593, a kappa-opioid receptor agonist, on carrageenin-induced peripheral oedema and Fos expression in the rat spinal cord
P478volume370

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Q34126256Endogenous opiates: 1999.cites workP2860

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