N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors

scientific article published in March 2003

N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-894X(03)00048-9
P698PubMed publication ID12643941
P5875ResearchGate publication ID10849967

P2093author name stringJohn C Lee
Jerry L Adams
Baoguang Zhao
Jeffrey C Boehm
Michael J Bower
Shouki Kassis
Zehong Wan
P2860cites workA protein kinase involved in the regulation of inflammatory cytokine biosynthesisQ24311139
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding siteQ27638349
Structural basis of inhibitor selectivity in MAP kinasesQ27765381
2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A(2B) receptorQ31916910
p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentialsQ33716182
Anti-TNF agents for rheumatoid arthritisQ34216181
Tumor necrosis factor-alpha blockade in the treatment of rheumatoid arthritisQ34276023
p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines.Q34483284
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinaseQ41141283
Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.Q42537136
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitutionQ42541263
Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor ComplexQ57899489
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potencyQ71591889
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1191-1194
P577publication date2003-03-01
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleN-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors
P478volume13

Reverse relations

Q34644067Radioiodinated O(6)-Benzylguanine derivatives containing an azido functioncites workP2860

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