Investigation of the mechanism of iron release from the C-lobe of human serum transferrin: mutational analysis of the role of a pH sensitive triad

scientific article published in April 2003

Investigation of the mechanism of iron release from the C-lobe of human serum transferrin: mutational analysis of the role of a pH sensitive triad is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI027071Q
P698PubMed publication ID12667060

P50authorQing-Yu HeQ37837220
P2093author name stringAnne B Mason
Ross T A MacGillivray
Stephen J Everse
Valerie C Smith
Sara K Briggs
Peter J Halbrooks
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)3701-3707
P577publication date2003-04-01
P1433published inBiochemistryQ764876
P1476titleInvestigation of the mechanism of iron release from the C-lobe of human serum transferrin: mutational analysis of the role of a pH sensitive triad
P478volume42

Reverse relations

cites work (P2860)
Q35776487A loop in the N-lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis, isothermal titration calorimetry, and epitope mapping
Q28508381A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase
Q36704757A structural comparison of human serum transferrin and human lactoferrin
Q36137942Beyond the Crystal Structure: Insight into the Function and Vaccine Potential of TbpA Expressed by Neisseria gonorrhoeae
Q36354191Biochemical and structural characterization of recombinant human serum transferrin from rice (Oryza sativa L.).
Q34169748Biological and clinical aspects of soluble transferrin receptor
Q47611075Computational approaches for deciphering the equilibrium and kinetic properties of iron transport proteins
Q84744092Computational structure models of apo and diferric transferrin-transferrin receptor complexes
Q41901589Conserved interaction between transferrin and transferrin-binding proteins from porcine pathogens
Q86962845Detailed molecular dynamics simulations of human transferrin provide insights into iron release dynamics at serum and endosomal pH
Q41189468Endosome-mitochondria interactions are modulated by iron release from transferrin.
Q28509618Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis
Q34102858Existence of a noncanonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry
Q42212432Genetically engineering transferrin to improve its in vitro ability to deliver cytotoxins
Q37322835Human serum transferrin: a tale of two lobes. Urea gel and steady state fluorescence analysis of recombinant transferrins as a function of pH, time, and the soluble portion of the transferrin receptor
Q41863900Human serum transferrin: is there a link among autism, high oxalate levels, and iron deficiency anemia?
Q37088674Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released
Q37148462Inequivalent contribution of the five tryptophan residues in the C-lobe of human serum transferrin to the fluorescence increase when iron is released
Q33945802Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery.
Q38748417Iron acquisition through the bacterial transferrin receptor
Q37893753Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH.
Q46420117Mathematical modeling of mutant transferrin-CRM107 molecular conjugates for cancer therapy
Q51459096Predicting long term cooperativity and specific modulators of receptor interactions in human transferrin from dynamics within a single microstate.
Q27677223Structural basis for iron piracy by pathogenic Neisseria
Q27643181Structure of the human transferrin receptor-transferrin complex
Q35850061The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding
Q27677337The structural basis of transferrin sequestration by transferrin-binding protein B
Q27662620The structure and evolution of the murine inhibitor of carbonic anhydrase: A member of the transferrin superfamily
Q33625506The unique kinetics of iron release from transferrin: the role of receptor, lobe-lobe interactions, and salt at endosomal pH
Q35511065Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry
Q27004133Transferrin-mediated cellular iron delivery

Search more.