(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

scientific article published in April 2003

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JM0204441
P8608Fatcat IDrelease_cv4qmvxzszhm5icascy2opucyq
P698PubMed publication ID12672235

P50authorLotte BrehmQ114443997
Jan EgebjergQ114443999
Tine B StensbølQ114444000
Hans Bräuner-OsborneQ37831020
Birgitte NielsenQ40334167
Kasper B. HansenQ41856981
P2093author name stringJeremy R Greenwood
Povl Krogsgaard-Larsen
Frank A Sløk
Tine T A Kronborg
P2860cites workThe reaction of (S)-alpha-phenylethylamine and isobuteraldehyde with benzoic acid and tert-butyl-isocyanide as model reactions for stereoselective peptide-synthesis intermediate. Four component condensationsQ71872673
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
P304page(s)1350-1358
P577publication date2003-04-01
P1433published inJournal of Medicinal ChemistryQ900316
P1476title(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology
P478volume46

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cites work (P2860)
Q45264602Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate
Q28290774Glutamate receptor ion channels: structure, regulation, and function
Q41883858Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus
Q44965385Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.

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