Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial

scientific article published on 13 June 2013

Effect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S2213-8587(13)70029-9
P698PubMed publication ID24622263

P50authorGiuseppe RemuzziQ16561003
Roberto TrevisanQ88185989
Piero RuggenentiQ92877106
Flavio GaspariQ92877115
Aneliya I ParvanovaQ114428690
Irene M van der MeerQ114428727
Ariela BenigniQ41002318
Antonio BossiQ58920685
Annalisa PernaQ84349157
P2093author name stringIlian Iliev
Daglutril in Diabetic Nephropathy Study Group
P2860cites workAvosentan reduces albumin excretion in diabetics with macroalbuminuriaQ24642372
Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studiesQ24658205
Cardiorenal end points in a trial of aliskiren for type 2 diabetesQ28278569
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathyQ29615215
A novel potent vasoconstrictor peptide produced by vascular endothelial cellsQ29620540
Towards triple vasopeptidase inhibitors for the treatment of cardiovascular diseases.Q30364697
Avosentan for overt diabetic nephropathyQ33702404
An update on: cardiovascular and respiratory changes during sleep in normal and hypertensive subjects.Q33869939
Clinical practice. Nephropathy in patients with type 2 diabetesQ34123307
Preventing microalbuminuria in type 2 diabetesQ34552302
Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathyQ34726905
New therapeutics that antagonize endothelin: promises and frustrationsQ35013988
Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: a multicentre, randomised, placebo-controlled study.Q35534210
Treatment of isolated systolic hypertension in diabetes mellitus type 2.Q36507647
Role of endothelin-1 in clinical hypertension: 20 years on.Q37234843
The RAAS in the pathogenesis and treatment of diabetic nephropathyQ37741783
The "J curve" problem revisited: old and new findingsQ37762755
Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteinsQ41267402
Atrial natriuretic peptide and prostacyclin synergistically mediate hyperfiltration and hyperperfusion of diabetic ratsQ41790822
The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension InvestigatorsQ42544459
A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trialQ43277549
Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 casesQ43593878
Combined inhibition of neutral endopeptidase with angiotensin converting enzyme or endothelin converting enzyme in experimental diabetesQ43928942
Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64).Q44242786
Inhibition of both neutral endopeptidase and endothelin-converting enzyme by SLV306 reduces proteinuria and urinary albumin excretion in diabetic ratsQ46444171
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force documentQ56970676
Prognostic accuracy of day versus night ambulatory blood pressure: a cohort studyQ57085479
Vasopeptidase inhibition and angio-oedemaQ74252375
Atrial natriuretic peptide increases urinary albumin excretion in people with normoalbuminuric type-2 diabetesQ80258843
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectplaceboQ269829
type 2 diabetesQ3025883
P304page(s)19-27
P577publication date2013-06-13
P1433published inThe Lancet: Diabetes & EndocrinologyQ27725107
P1476titleEffect on blood pressure of combined inhibition of endothelin-converting enzyme and neutral endopeptidase with daglutril in patients with type 2 diabetes who have albuminuria: a randomised, crossover, double-blind, placebo-controlled trial
P478volume1

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cites work (P2860)
Q38225794Current state of endothelin receptor antagonism in hypertension and pulmonary hypertension
Q36441616Diabetic nephropathy: What does the future hold?
Q38373858Drug therapy for the patient with resistant hypertension
Q26752292Dual inhibition of renin-angiotensin-aldosterone system and endothelin-1 in treatment of chronic kidney disease
Q35984860Effects of endopeptidase inhibition on the relaxation response of isolated human penile erectile tissue to vasoactive peptides.
Q26767156Endothelin
Q35182125Endothelin A receptor antagonist, atrasentan, attenuates renal and cardiac dysfunction in Dahl salt-hypertensive rats in a blood pressure independent manner
Q34437692Endothelin and endothelin antagonists in chronic kidney disease
Q28246158Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12
Q64443714Endothelins in cardiovascular biology and therapeutics
Q90046724New Molecules for Treating Resistant Hypertension: a Clinical Perspective
Q38429870New developments in the pharmacological treatment of hypertension: dead-end or a glimmer at the horizon?
Q37620461Novel approaches for treating hypertension
Q39170387Novel avenues for treating diabetic nephropathy: new investigational drugs.
Q38265818Novel effective drugs for diabetic kidney disease? or not?
Q30374407Pleiotropic effects of type 2 diabetes management strategies on renal risk factors.
Q34472913Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials
Q38269052The role of endothelin-1 in pulmonary arterial hypertension
Q38678678Therapeutic potential of endothelin receptor antagonism in kidney disease

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