Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression

scientific article published on 29 April 2003

Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00487.2002
P698PubMed publication ID12721153
P5875ResearchGate publication ID7384974

P50authorNestor F Gonzalez-CadavidQ92730697
Jorge N. ArtazaQ122229070
Con MallidisQ42531539
Shalender BhasinQ64495451
P2093author name stringKun Ma
Behrouz Salehian
Jose Arias
Vahid Mahabadi
P2860cites workOrganization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wastingQ22008491
Regulation of myostatin activity and muscle growthQ24555817
Double muscling in cattle due to mutations in the myostatin geneQ24648136
Myostatin and the control of skeletal muscle massQ28145470
Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1Q28204465
Turnover of skeletal muscle contractile proteins in glucocorticoid myopathyQ28245961
Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattleQ28250102
Blockade of glucocorticoid receptor binding and inhibition of dexamethasone-induced muscle atrophy in the rat by RU38486, a potent glucocorticoid antagonistQ28336948
Time course of the effect of catabolic doses of corticosterone on protein turnover in rat skeletal muscle and liverQ28365905
C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscleQ28565301
Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flightQ28577604
Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cellsQ31833462
Glucocorticoids and muscle catabolismQ33716942
Postnatal glucocorticosteroid therapy for treatment and prevention of neonatal chronic lung diseaseQ34074665
Control of muscle development by dueling HATs and HDACsQ34088887
A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattleQ34438337
Molecular regulation of muscle cachexia: it may be more than the proteasomeQ34485774
Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroidsQ34529658
Control of muscle protein breakdown: effects of activity and nutritional statesQ34577967
Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in agingQ35765499
Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoidsQ37350232
Myostatin is an inhibitor of myogenic differentiation.Q40739514
Endogenous expression and localization of myostatin and its relation to myosin heavy chain distribution in C2C12 skeletal muscle cellsQ40755294
Myostatin regulates cell survival during C2C12 myogenesisQ40829857
Transcription factors and asthmaQ40846857
Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathwayQ41249327
Effect of corticosterone administration at varying levels on leucine oxidation and whole body protein synthesis and breakdown in adrenalectomized ratsQ42053038
Characterization of 5'-regulatory region of human myostatin gene: regulation by dexamethasone in vitroQ44226350
Electrophoretic separation of rat skeletal muscle myosin heavy-chain isoforms.Q45940714
Glucocorticoid-induced atrophy in different fibre types of selected rat jaw and hind-limb musclesQ49067804
Effects of glucocorticoid treatment and food restriction on rat hindlimb musclesQ49162383
P433issue2
P304page(s)E363-71
P577publication date2003-04-29
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleGlucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression
P478volume285

Reverse relations

cites work (P2860)
Q37218921A Role for Myokines in Muscle-Bone Interactions
Q35993669A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure.
Q46513116A comparative examination of cortisol effects on muscle myostatin and HSP90 gene expression in salmonids.
Q44523986A membrane glucocorticoid receptor mediates the rapid/non-genomic actions of glucocorticoids in mammalian skeletal muscle fibres.
Q34785536A soluble activin receptor type IIB does not improve blood glucose in streptozotocin-treated mice
Q30496704Acute daily psychological stress causes increased atrophic gene expression and myostatin-dependent muscle atrophy
Q35622374Age-related changes in thirst, salt appetite, and arterial blood pressure in response to aldosterone-dexamethasone combination in rats
Q90295069Amelioration of muscle wasting by glucagon-like peptide-1 receptor agonist in muscle atrophy
Q37546849An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy
Q42465386An evolutionarily conserved Myostatin proximal promoter/enhancer confers basal levels of transcription and spatial specificity in vivo.
Q46657318An unusual lipomatous brain mass in a Golden Retriever dog.
Q24795157Antiglucocorticoid RU38486 reduces net protein catabolism in experimental acute renal failure
Q48514411Blocking extracellular activation of myostatin as a strategy for treating muscle wasting
Q34429152CCAAT/enhancer binding protein-δ expression is increased in fast skeletal muscle by food deprivation and regulates myostatin transcription in vitro
Q36648792Cancer cachexia: it's time for more clinical trials
Q40987037Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia
Q42250061Cardiac and vascular atrogin-1 mRNA expression is not associated with dexamethasone efficacy in the monocrotaline model of pulmonary hypertension
Q26744140Cardiac cachexia: hic et nunc
Q35683683Changes in Serum Levels of Myokines and Wnt-Antagonists after an Ultramarathon Race
Q38338967Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells.
Q36861023Clinical, agricultural, and evolutionary biology of myostatin: a comparative review
Q37270488Coordinated patterns of gene expressions for adult muscle build-up in transgenic mice expressing myostatin propeptide
Q98944959Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms
Q46538025Developmental reprogramming of rat GLUT5 requires glucocorticoid receptor translocation to the nucleus
Q35667262Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats
Q51681547Differential sensitivity of oxidative and glycolytic muscles to hypoxia-induced muscle atrophy.
Q43252739Dissociation of local anti-inflammatory effect and systemic effects of mometasone furoate in mice
Q51362680Effect of active immunization against a recombinant mouse granulocyte-macrophage colony-stimulating factor/somatostatin fusion protein on the growth of mice.
Q43239281Effect of dietary probiotics on clownfish: a molecular approach to define how lactic acid bacteria modulate development in a marine fish
Q34489678Effects of an immunosuppressive treatment in the GRMD dog model of Duchenne muscular dystrophy
Q37609256Effects of concentric and eccentric muscle actions on serum myostatin and follistatin-like related gene levels
Q83812471Effects of pre-exercise feeding on serum hormone concentrations and biomarkers of myostatin and ubiquitin proteasome pathway activity
Q84712742Effects of transforming growth factor-beta (TGF-β1) on satellite cell activation and survival during oxidative stress
Q37791182Effects of type 1 diabetes mellitus on skeletal muscle: clinical observations and physiological mechanisms
Q35083601Elimination of myostatin does not combat muscular dystrophy in dy mice but increases postnatal lethality
Q41658783Embryonic and tissue-specific regulation of myostatin-1 and -2 gene expression in zebrafish
Q37389085Estradiol in females may negate skeletal muscle myostatin mRNA expression and serum myostatin propeptide levels after eccentric muscle contractions
Q46932793Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats
Q43228354Exercise training prevents hyperinsulinemia, muscular glycogen loss and muscle atrophy induced by dexamethasone treatment
Q49681521Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease
Q43286525Expression of genes related to myostatin signaling during rat skeletal muscle longitudinal growth
Q82437478Expression of myostatin RNA transcript and protein in gastrocnemius muscle of rats after sciatic nerve resection
Q40239056Expression pattern of myostatin in gastrocnemius muscle of rats after sciatic nerve crush injury
Q44266626Expression profiling of skeletal muscle in young bulls treated with steroidal growth promoters.
Q91580018G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells
Q37250460Gender differences in body composition deficits at diagnosis in children and adolescents with Crohn's disease
Q80796644Gender dimorphism influences extracellular matrix expression and regeneration of muscular tissue in mdx dystrophic mice
Q64927268Glucocorticoid-induced CREB activation and myostatin expression in C2C12 myotubes involves phosphodiesterase-3/4 signaling.
Q35135088Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism
Q36030304Glucocorticoids Enhance Muscle Proteolysis through a Myostatin-Dependent Pathway at the Early Stage
Q91916997Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle
Q34067618Glucocorticoids increase salt appetite by promoting water and sodium excretion
Q39681574Glutamine prevents myostatin hyperexpression and protein hypercatabolism induced in C2C12 myotubes by tumor necrosis factor-α.
Q44970167Growth hormone differentially regulates muscle myostatin1 and -2 and increases circulating cortisol in rainbow trout (Oncorhynchus mykiss).
Q38739971Heat Stress Modulates Both Anabolic and Catabolic Signaling Pathways Preventing Dexamethasone-Induced Muscle Atrophy In Vitro
Q42747919Histomorphometric changes in the perirenal adipocytes of adrenalectomized rats treated with dexamethasone
Q36665191Hormonal receptors in skeletal muscles of dystrophic mdx mice
Q57300292Hypoglycemic Properties of the Aqueous Extract from the Stem Bark of in Dexamethasone-Induced Insulin Resistant Rats
Q39919378Hypothyroidism is associated with increased myostatin expression in rats.
Q51820504Impact of exercise training on myostatin expression in the myocardium and skeletal muscle in a chronic heart failure model.
Q34586285Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit
Q38017953Implications of glucocorticoid therapy in idiopathic inflammatory myopathies
Q35536351Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia
Q36001532Interaction between muscle and bone, and improving the effects of electrical muscle stimulation on amyotrophy and bone loss in a denervation rat model via sciatic neurectomy
Q38617041Intermittent Glucocorticoid Dosing Improves Muscle Repair and Function in Mice with Limb Girdle Muscular Dystrophy
Q39714216L6E9 myoblasts are deficient of myostatin and additional TGF-beta members are candidates to developmentally control their fiber formation.
Q34429462Lactobacillus rhamnosus accelerates zebrafish backbone calcification and gonadal differentiation through effects on the GnRH and IGF systems
Q35086825Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women
Q47936364Linkage of myostatin pathway genes with knee strength in humans
Q85358877Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets
Q44489665Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin
Q34447001METABOLIC FUNCTIONS OF MYOSTATIN AND GDF11.
Q42485411Maintenance of the spinal nucleus of the bulbocavernosus neuromuscular system is not influenced by physiological levels of glucocorticoids
Q38890362Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres
Q38092488Metabolic functions of glucocorticoid receptor in skeletal muscle
Q38207093Minireview: new molecular mediators of glucocorticoid receptor activity in metabolic tissues
Q33349016Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy
Q50900869Molecular characterization of myostatin from the skeletal muscle of the African lungfish, Protopterus annectens, and changes in its mRNA and protein expression levels during three phases of aestivation.
Q38353108Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse
Q35939993Muscle torque relative to cross-sectional area and the functional muscle-bone unit in children and adolescents with chronic disease
Q51188121Muscle wasting in collagen-induced arthritis and disuse atrophy.
Q36647399Muscle-specific microRNA1 (miR1) targets heat shock protein 70 (HSP70) during dexamethasone-mediated atrophy.
Q54450832Myostatin and follistatin expression in skeletal muscles of rats with chronic heart failure.
Q42994266Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice
Q37635807Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake
Q36515547Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects
Q34629780Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction.
Q38292770Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice
Q26797484Myostatin: expanding horizons
Q36687329Neck muscle cross-sectional area, brain volume and cognition in healthy older men: a cohort study.
Q35855917Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation
Q33544449Normalizing RT-qPCR data: are we getting the right answers? An appraisal of normalization approaches and internal reference genes from a case study in the finfish Lates calcarifer
Q34378165Pathological fractures in paediatric patients with inflammatory bowel disease
Q90704987Perioperative Changes in the Psoas Muscle Index in Patients Undergoing ABO-Incompatible Living-Donor Liver Transplantation: A Single-Center Experience
Q42011965Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy
Q48120255Phylogenetic analysis of the myostatin gene sub-family and the differential expression of a novel member in zebrafish
Q55053966Physiological elevation of endogenous hormones results in superior strength training adaptation.
Q36881964Plasticity of human skeletal muscle: gene expression to in vivo function.
Q34501675Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle
Q26996234Posttransplant sarcopenia: an underrecognized early consequence of liver transplantation
Q41898403Protein and Amino Acid Supplementation Does Not Alter Proteolytic Gene Expression following Immobilization
Q51309321Quantitative and qualitative adaptations of muscle fibers to glucocorticoids.
Q64238830Quercetin glycosides prevent dexamethasone-induced muscle atrophy in mice
Q28564515Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats
Q38135640Revisiting the paradigm of myostatin in vertebrates: insights from fishes
Q64988797Rheumatoid arthritis in remission : Decreased myostatin and increased serum levels of periostin.
Q35166254Role of TGF-β signaling in inherited and acquired myopathies
Q26825916Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds
Q33925571Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice
Q42949695Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle
Q45329196Serum myostatin levels and grip strength in normal subjects and patients on maintenance haemodialysis.
Q64891195Skeletal Muscle Response to Deflazacort, Dexamethasone and Methylprednisolone.
Q37890215Steroid myopathy: some unresolved issues.
Q54572065Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans.
Q34771160Systematic review: body composition in adults with inflammatory bowel disease
Q43095052TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice.
Q38982057TRAF6 inhibition rescues dexamethasone-induced muscle atrophy
Q41825244Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases.
Q35739702Targeting the myostatin signaling pathway to treat muscle wasting diseases
Q42726736Testosterone reduced methylprednisolone-induced muscle atrophy in spinal cord-injured rats
Q22242626The aetiology and impact of malnutrition in paediatric inflammatory bowel disease
Q33864678The effects of exogenous cortisol on myostatin transcription in rainbow trout, Oncorhynchus mykiss
Q37713606The function of myostatin in the regulation of fat mass in mammals
Q28592692The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy
Q36607060The molecular mechanisms of skeletal muscle wasting: implications for therapy.
Q49034737The pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells in chronic kidney disease
Q37103765The pituitary-adrenal axis and body composition
Q92401998The sodium-glucose cotransporter 2 inhibitor luseogliflozin can suppress muscle atrophy in Db/Db mice by suppressing the expression of foxo1
Q33910776Time course expression of Foxo transcription factors in skeletal muscle following corticosteroid administration
Q28569232Transcription factors in muscle atrophy caused by blocked neuromuscular transmission and muscle unloading in rats
Q40177102Transcriptional pathways associated with skeletal muscle disuse atrophy in humans
Q56171520Welfare improvement using alginic acid in rainbow trout (Oncorhynchus mykiss) juveniles
Q34004260Whole body cortisol and expression of HSP70, IGF-I and MSTN in early development of sea bass subjected to heat shock
Q44682872mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass

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