N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress

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N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress is …
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scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00355.2002
P698PubMed publication ID12799318
P5875ResearchGate publication ID10715192

P50authorAdria GiaccaQ80162695
P2093author name stringElena Bogdanovic
I George Fantus
Tony K T Lam
Neehar Gupta
Zhiwen Yu
C Andrew Haber
Tracy Goh
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Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.Q34237007
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Oxidative stress and diabetic vascular complicationsQ34391178
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Protein kinase C activation and the development of diabetic complicationsQ34469779
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitusQ34541876
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In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious ratsQ35750029
Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicityQ35768419
Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.Q36590164
Glucose-induced phosphorylation of the insulin receptor. Functional effects and characterization of phosphorylation sitesQ37351595
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Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activityQ37393990
Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase CQ39575897
Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathwaysQ40912879
Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistanceQ40934232
Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).Q41020366
Contributions to senescence: non-enzymatic glycosylation of proteinsQ41452034
Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageingQ41845928
The antioxidant action of taurine, hypotaurine and their metabolic precursorsQ41878907
High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytesQ42489573
alpha-Lipoic acid prevents the development of glucose-induced insulin resistance in 3T3-L1 adipocytes and accelerates the decline in immunoreactive insulin during cell incubationQ42510095
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injuryQ42816281
Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocationQ42817438
Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytesQ42826146
Glucose-induced insulin resistance of skeletal-muscle glucose transport and uptakeQ42858446
Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).Q43681994
Elevated lipid peroxidation levels in red blood cells of streptozotocin-treated diabetic ratsQ43777075
Effect of intravenous taurine on endotoxin-induced acute lung injury in sheepQ43804496
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima IndiansQ43850960
The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding.Q51558704
Improvement of insulin-stimulated glucose-disposal in type 2 diabetes after repeated parenteral administration of thioctic acid.Q51583621
Evidence for a relationship between oxidative stress and insulin action in non-insulin-dependent (type II) diabetic patients.Q51592930
Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial.Q54080708
Insulin resistance in rats with non-insulin-dependent diabetes induced by neonatal (5 days) streptozotocin: evidence for reversal following phlorizin treatment.Q54318715
Meal-induced oxidative stress and low-density lipoprotein oxidation in diabetes: The possible role of hyperglycemiaQ58829265
Meal-Generated Oxidative Stress in Type 2 Diabetic PatientsQ58829300
Early and late insulin response as predictors of NIDDM in Pima Indians with impaired glucose toleranceQ59150861
P433issue4
P921main subjecthyperglycemiaQ271993
acetylcysteineQ375613
insulin resistanceQ1053470
preproinsulinQ7240673
P304page(s)E744-53
P577publication date2003-06-10
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleN-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress
P478volume285

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