Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease

scientific article

Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1046/J.1471-4159.2003.01808.X
P698PubMed publication ID12807434
P5875ResearchGate publication ID10708424

P2093author name stringSeong Who Kim
Hyun Jin Choi
Onyou Hwang
So Yeon Lee
P2860cites workOxygen toxicity, oxygen radicals, transition metals and diseaseQ29615096
Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.Q36899240
Activation of endogenous antioxidant defenses in neuronal cells prevents free radical-mediated damage.Q41029391
Oxidative stress and the pathogenesis of Parkinson's diseaseQ41262986
Neuronal vulnerability in Parkinson's disease.Q41446817
Identification of catechol-protein conjugates in neostriatal slices incubated with [3H]dopamine: impact of ascorbic acid and glutathioneQ72109104
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectParkinson's diseaseQ11085
dopamineQ170304
cytotoxicityQ246181
sapropterinQ419808
neurodegenerationQ1755122
P304page(s)143-152
P577publication date2003-07-01
P1433published inJournal of NeurochemistryQ6295643
P1476titleDopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease
P478volume86

Reverse relations

cites work (P2860)
Q53203837A Novel Compound ITC-3 Activates the Nrf2 Signaling and Provides Neuroprotection in Parkinson's Disease Models.
Q36147318A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP.
Q39993979A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells
Q36123780A novel synthetic isothiocyanate ITC-57 displays antioxidant, anti-inflammatory, and neuroprotective properties in a mouse Parkinson's disease model
Q38869276Alteration of striatal tetrahydrobiopterin in iron-induced unilateral model of Parkinson's disease
Q38603276Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues
Q37482974Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta
Q37260391Approaches to prevent dopamine quinone-induced neurotoxicity
Q48481582Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity
Q37622166Developmental susceptibility of neurons to transient tetrahydrobiopterin insufficiency and antenatal hypoxia-ischemia in fetal rabbits
Q37717851Dopamine Cytotoxicity Involves Both Oxidative and Nonoxidative Pathways in SH-SY5Y Cells: Potential Role of Alpha-Synuclein Overexpression and Proteasomal Inhibition in the Etiopathogenesis of Parkinson's Disease
Q37629253Dopamine-induced behavioral changes and oxidative stress in methamphetamine-induced neurotoxicity
Q45937480Doxycycline is neuroprotective against nigral dopaminergic degeneration by a dual mechanism involving MMP-3.
Q36702899Early infant exposure to excess multivitamin: a risk factor for autism?
Q46514011Glia cell number modulates sensitivity to MPTP in mice
Q39064885Inactivation of Aconitase by Tetrahydrobiopterin in DArgic Cells: Relevance to PD.
Q38907367Induction of NQO1 and Neuroprotection by a Novel Compound KMS04014 in Parkinson's Disease Models
Q52677431Interaction of genetic and environmental factors in a Drosophila parkinsonism model.
Q90732124Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis
Q36285084L-DOPA treatment from the viewpoint of neuroprotection. Possible mechanism of specific and progressive dopaminergic neuronal death in Parkinson's disease
Q92662264Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease
Q33883174Matrix metalloproteinase-3 is increased and participates in neuronal apoptotic signaling downstream of caspase-12 during endoplasmic reticulum stress
Q34217427Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice
Q36607332Nonsteroidal anti-inflammatory drugs in Parkinson's disease: possible involvement of quinone formation
Q38645013Potential repositioning of exemestane as a neuroprotective agent for Parkinson's disease
Q64067591Regulation of the Nrf2 Pathway by Glycogen Synthase Kinase-3β in MPP⁺-Induced Cell Damage
Q24684947Sepiapterin reductase expression is increased in Parkinson's disease brain tissue
Q47103259Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation
Q57697189Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model
Q39686769p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration

Search more.