Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells

scientific article published in August 2003

Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0887-2333(03)00051-1
P8608Fatcat IDrelease_x72hoghlerbblcdylk5qadejp4
P698PubMed publication ID12849726

P2093author name stringRoss D
Ali AM
Annuar BO
Inayat-Hussain SH
Din LB
P2860cites workMitochondrion as a novel target of anticancer chemotherapyQ33958275
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Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cellsQ36273817
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell deathQ36365164
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Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cellsQ78170671
Styryl-lactone derivatives and alkaloids from Goniothalamus borneensis (Annonaceae)Q104919943
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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3Q24324482
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosisQ24653321
Mitochondrial release of caspase-2 and -9 during the apoptotic processQ24676806
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosisQ28250587
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerizationQ28275527
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisQ28292299
The biochemistry of apoptosisQ29547741
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosisQ29616513
Strategies for discovering drugs from previously unexplored natural productsQ30880493
The pharmacology of apoptosis.Q33547883
Corpse clearance defines the meaning of cell deathQ33922730
P433issue4
P921main subjecttransmembrane proteinQ424204
P304page(s)433-439
P577publication date2003-08-01
P1433published inToxicology in VitroQ15716678
P1476titleLoss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells
P478volume17