Convulxin binds to native, human glycoprotein Ib alpha

scientific article published on 24 July 2003

Convulxin binds to native, human glycoprotein Ib alpha is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M300199200
P698PubMed publication ID12881531

P2093author name stringTaisuke Kanaji
Sachiko Kanaji
Thomas J Kunicki
Kazunobu Kato
Kenichi Furihata
Jerry L Ware
P2860cites workStructures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domainQ24304907
Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin bindingQ24314966
Cloning of the murine platelet glycoprotein Ibalpha gene highlighting species-specific platelet adhesionQ24316137
Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptorQ24321786
Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activationQ27639267
Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndromeQ28509360
Alboaggregin A activates platelets by a mechanism involving glycoprotein VI as well as glycoprotein Ib.Q31835076
Cloning of subunits of convulxin, a collagen-like platelet-aggregating protein from Crotalus durissus terrificus venomQ32055796
The use of snake venom toxins as tools to study platelet receptors for collagen and von Willebrand factor.Q34574842
Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditionsQ37377651
Tyrosine sulfation of the glycoprotein Ib-IX complex: identification of sulfated residues and effect on ligand bindingQ38302282
Tyrosine sulfation of glycoprotein I(b)alpha. Role of electrostatic interactions in von Willebrand factor bindingQ40816257
Aggretin, a novel platelet-aggregation inducer from snake (Calloselasma rhodostoma) venom, activates phospholipase C by acting as a glycoprotein Ia/IIa agonistQ41982549
Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactionsQ43513939
Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to α2β1 integrin and glycoprotein Ib, activating Syk and phospholipase Cγ 2, but does not involve the glycoprotein VI/Fc receptQ43565303
Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein IbalphaQ43607754
Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signalingQ43627739
Variation in human platelet glycoprotein VI content modulates glycoprotein VI-specific prothrombinase activityQ43794454
Physical proximity and functional interplay of the glycoprotein Ib-IX-V complex and the Fc receptor FcgammaRIIA on the platelet plasma membraneQ46043210
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletionQ52550457
Convulxin Binding to Platelet Receptor GPVI: Competition with Collagen Related PeptidesQ56922097
COnvulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to plateletsQ58868110
Adhesion and activation of human platelets induced by convulxin involve glycoprotein VI and integrin alpha2beta1Q73813682
P433issue41
P407language of work or nameEnglishQ1860
P304page(s)39452-39460
P577publication date2003-07-24
P1433published inJournal of Biological ChemistryQ867727
P1476titleConvulxin binds to native, human glycoprotein Ib alpha
P478volume278

Reverse relations

cites work (P2860)
Q51751581A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.
Q24306293A role for the thiol isomerase protein ERP5 in platelet function
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Q33235078Crystallization and preliminary X-ray crystallographic analysis of agkicetin-C from Deinagkistrodon acutus venom.
Q55468635Dysfunctional platelet membrane receptors: from humans to mice.
Q38313409Effect of multimer size and a natural dimorphism on the binding of convulxin to platelet glycoprotein (GP)VI.
Q44941572GPIb potentiates GPVI-induced responses in human platelets.
Q35891646GPIbα regulates platelet size by controlling the subcellular localization of filamin
Q28267414GPVI and integrin alphaIIb beta3 signaling in platelets
Q28587122Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function
Q33404311Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen
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Q64085112Structurally Robust and Functionally Highly Versatile-C-Type Lectin (-Related) Proteins in Snake Venoms
Q28168596The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented
Q40526832The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha 2 beta 1.
Q35752946The role of collagen in thrombosis and hemostasis
Q47722052Von Willebrand factor present in fibrillar collagen enhances platelet adhesion to collagen and collagen-induced platelet aggregation
Q33411711von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3.