scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1046402466 |
P356 | DOI | 10.1038/SJ.LEU.2403111 |
P698 | PubMed publication ID | 12931221 |
P5875 | ResearchGate publication ID | 10603738 |
P2093 | author name string | Bortul R | |
Martelli AM | |||
Zweyer M | |||
Tabellini G | |||
Tazzari PL | |||
Cocco L | |||
Billi AM | |||
Cappellini A | |||
Falà F | |||
P2860 | cites work | Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications | Q44098361 |
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells | Q44133598 | ||
Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemia | Q44279382 | ||
Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation | Q44319730 | ||
Retinoblastoma protein-overexpressing HL60 cells resistant to 1,25-dihydroxyvitamin D3 display increased CDK2 and CDK6 activity and shortened G1 phase | Q47886741 | ||
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies | Q57591287 | ||
Breast cancer banishes p27 from nucleus | Q78306567 | ||
Direct control of the Forkhead transcription factor AFX by protein kinase B | Q22009452 | ||
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. | Q24514761 | ||
CDK inhibitors: positive and negative regulators of G1-phase progression | Q27860983 | ||
DNA replication in eukaryotic cells | Q28131747 | ||
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer | Q28203143 | ||
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2 | Q28216784 | ||
CREB is a regulatory target for the protein kinase Akt/PKB | Q28289946 | ||
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B | Q28638147 | ||
The protein kinase B/Akt signalling pathway in human malignancy | Q28645742 | ||
Cell cycle and death control: long live Forkheads | Q28646130 | ||
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 | Q29617416 | ||
SHIPs ahoy | Q33785109 | ||
Safety and antitumor activity of recombinant soluble Apo2 ligand | Q33855449 | ||
AKT plays a central role in tumorigenesis | Q33944165 | ||
Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. | Q34099883 | ||
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization | Q34150579 | ||
Forkhead transcription factors are targets of signalling by the proto-oncogene PKB (C-AKT). | Q34150787 | ||
Checking out the G(2)/M transition. | Q34282259 | ||
Ten years of protein kinase B signalling: a hard Akt to follow | Q34432885 | ||
Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes | Q34493133 | ||
Regulation of cyclin-Cdk activity in mammalian cells | Q34531931 | ||
The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system. | Q34973870 | ||
New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? | Q35057304 | ||
Flow cytometric detection of total and serine 473 phosphorylated Akt. | Q40636307 | ||
Inactivation of the forkhead transcription factor FoxO3 is essential for PKB-mediated survival of hematopoietic progenitor cells by kit ligand | Q40656051 | ||
A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells | Q40686902 | ||
Regulation of myeloma cell growth through Akt/Gsk3/forkhead signaling pathway | Q40700367 | ||
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest | Q40702262 | ||
Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. | Q40831748 | ||
Mutational analysis of the tumour suppressor gene MMAC1/PTEN in malignant myeloid disorders | Q40857867 | ||
Mutation analysis of PTEN/MMAC1 in acute myeloid leukemia | Q40895282 | ||
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. | Q40975748 | ||
P433 | issue | 11 | |
P304 | page(s) | 2157-2167 | |
P577 | publication date | 2003-11-01 | |
P1433 | published in | Leukemia | Q6534498 |
P1476 | title | The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression | |
P478 | volume | 17 |
Q38140625 | "Role of the B-cell receptor and the microenvironment in chronic lymphocytic leukemia''. |
Q33628050 | Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells |
Q26753162 | Autophagy and Apoptotic Crosstalk: Mechanism of Therapeutic Resistance in HER2-Positive Breast Cancer |
Q54503032 | Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/β-catenin signaling and FOXO1. |
Q38939358 | Bone marrow stromal cells protect acute myeloid leukemia cells from anti-CD44 therapy partly through regulating PI3K/Akt-p27(Kip1) axis |
Q37919105 | Constitutional trisomy 8p11.21-q11.21 mosaicism: a germline alteration predisposing to myeloid leukaemia |
Q47220725 | Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway |
Q42035414 | Down Regulation of FOXO1 Promotes Cell Proliferation in Cervical Cancer |
Q40330305 | ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase |
Q47547404 | Epstein-Barr Virus Susceptibility in Activated PI3Kδ Syndrome (APDS) Immunodeficiency |
Q37670417 | Exploiting cellular pathways to develop new treatment strategies for AML. |
Q34129824 | FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol |
Q46845164 | Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients |
Q34043823 | Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer |
Q36515948 | Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor |
Q33584982 | Metallothioneins regulate the adipogenic differentiation of 3T3-L1 cells via the insulin signaling pathway |
Q40846602 | MiR-374a promotes the proliferation of human osteosarcoma by downregulating FOXO1 expression |
Q39351860 | MicroRNA-223 regulates FOXO1 expression and cell proliferation |
Q35742539 | MicroRNA-3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation |
Q36571466 | MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma |
Q36384731 | Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival |
Q92207064 | Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus |
Q37579286 | New agents in acute myeloid leukemia: beyond cytarabine and anthracyclines |
Q40492173 | Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway |
Q37486934 | Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis. |
Q41772799 | Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia |
Q64377131 | Peroxisome proliferator-activated receptor gamma and retinoic acid receptor synergistically up-regulate the tumor suppressor PTEN in human promyeloid leukemia cells |
Q40382560 | Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias |
Q40488705 | Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells |
Q36461618 | Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. |
Q33751778 | Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen |
Q46956224 | Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells |
Q34042949 | Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors |
Q42509077 | SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation |
Q38800014 | Shikonin Derivative DMAKO-05 Inhibits Akt Signal Activation and Melanoma Proliferation. |
Q33842071 | Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells |
Q30482505 | The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals |
Q56995355 | The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion |
Q40291978 | The role of the nuclear Akt activation and Akt inhibitors in all-trans-retinoic acid-differentiated HL-60 cells |
Q35781570 | miR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway |
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