BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.

scientific article published in August 2003

BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID12941809

P50authorSuet Yi LeungQ67415790
P2093author name stringWei Zhao
Tsun L Chan
Siu T Yuen
Cancer Genome Project
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)4878-4881
P577publication date2003-08-01
P1433published inCancer ResearchQ326097
P1476titleBRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
P478volume63

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cites work (P2860)
Q92620116A Role for the WNT Co-Receptor LRP6 in Pathogenesis and Therapy of Epithelial Cancers
Q80988302A case of multiple protruding and flat colorectal tumors analyzed by a cDNA array
Q27852431A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.
Q35071477A serrated colorectal cancer pathway predominates over the classic WNT pathway in patients with hyperplastic polyposis syndrome
Q37635945APC and its modifiers in colon cancer.
Q35475357Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
Q38798435Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer
Q97543614After Nf1 loss in Schwann cells, inflammation drives neurofibroma formation
Q35915905Apoptosis and colorectal cancer
Q47753304BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability
Q35588657BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs
Q42353442BRAF inhibitor treatment of melanoma causing colonic polyps: An alternative hypothesis
Q35596687BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
Q36613576BRAF mutations and phosphorylation status of mitogen-activated protein kinases in the development of flat and depressed-type colorectal neoplasias
Q21245742BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status
Q35083792BRAF mutations in aberrant crypt foci and hyperplastic polyposis
Q28543370BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications
Q33868608BRAF, K-ras and BAT26 mutations in colorectal polyps and stool.
Q37457106Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation
Q34000694Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells
Q38690051British Society of Gastroenterology position statement on serrated polyps in the colon and rectum
Q28259527Cancer stem cells: the lessons from pre-cancerous stem cells
Q89638302Capicua suppresses colorectal cancer progression via repression of ETV4 expression
Q34369345Claudin-1 Expression Is Elevated in Colorectal Cancer Precursor Lesions Harboring the BRAF V600E Mutation
Q41875891Clinicopathologic Significance of BRAF Mutation and Extracellular Signal Regulated Kinase 1/2 Expression in Patients With a Colorectal Adenocarcinoma
Q36567499Clinicopathologic and genetic characterization of traditional serrated adenomas of the colon
Q35175269Clonality and evolutionary history of rhabdomyosarcoma
Q34997425Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency
Q34359322Comprehensive mutation analysis in colorectal flat adenomas
Q40305624Cooperation of BRAF(F595L) and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling
Q33904170DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability
Q61865606DNA methylation changes in ex-adenoma carcinoma of the large intestine
Q33754380DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
Q37164481Deficient DNA mismatch repair is common in Lynch syndrome-associated colorectal adenomas
Q53141713Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.
Q37129749Detection of up to 65% of Precancerous Lesions of the Human Colon and Rectum by Mutation Analysis of APC, K-Ras, B-Raf and CTNNB1.
Q33541307Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study
Q41553206Distinct clinicopathological features in metanephric adenoma harboring BRAF mutation.
Q42755415Distinctive crypt shape in a sessile serrated adenoma/polyp: Distribution of Ki67-, p16INK4a-, WNT5A-positive cells and intraepithelial lymphocytes
Q39704117Down-regulation of HLA-A mRNA in peripheral blood mononuclear cell of colorectal cancer
Q54577179EGF genetic polymorphism is associated with clinical features but not malignant phenotype in neurofibromatosis type 1 patients.
Q27021798Endoscopic and histologic characteristics of serrated lesions
Q33855895Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia
Q36529734Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma
Q81142727Expression of cytokeratins 7 and 20 in serrated adenoma and related diseases
Q51134123Extent of field change in colorectal cancers with BRAF mutation.
Q64905926Fast and efficient microfluidic cell filter for isolation of circulating tumor cells from unprocessed whole blood of colorectal cancer patients.
Q92840751Frequent CpG island methylation: a risk factor in the progression of traditional serrated adenoma of the colorectum
Q35024163Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma.
Q37040359Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.
Q46729226Gene profiling of colonic serrated adenomas by using oligonucleotide microarray
Q52670882Genetic Biopsy for Prediction of Surveillance Intervals after Endoscopic Resection of Colonic Polyps: Results of the GENESIS Study.
Q37122495Genetic diagnosis strategy of hereditary non-polyposis colorectal cancer
Q38191462Genetic unraveling of colorectal cancer
Q92716660Genomics and metagenomics of colorectal cancer
Q36563097HLA Class I Expressions on Peripheral Blood Mononuclear Cells in Colorectal Cancer Patients
Q35875965HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences
Q36717750Highly sensitive, non-invasive detection of colorectal cancer mutations using single molecule, third generation sequencing
Q48657546Histopathological diagnosis and differential diagnosis of colorectal serrated polys: findings of a consensus conference of the working group "gastroenterological pathology of the German Society of Pathology"
Q42145847Hyperplastic Polyposis Syndrome Identified with a BRAF Mutation
Q36401708Hyperplastic polyps and the risk of adenoma recurrence in the polyp prevention trial
Q34867868Immunohistochemistry - microarray analysis of patients with peritoneal metastases of appendiceal or colorectal origin
Q36850060Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.
Q39514200Inflammatory response in serrated precursor lesions of the colon classified according to WHO entities, clinical parameters and phenotype-genotype correlation.
Q28083455Interleukin-1 loop model for pathogenesis of Langerhans cell histiocytosis
Q33828527Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome
Q34224853Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma
Q34720314Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.
Q34614910Management of serrated adenomas and hyperplastic polyps
Q58724203Merkel cell polyomavirus and Langerhans cell neoplasm
Q35596441Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer
Q30811836Molecular analysis of the EGFR-RAS-RAF pathway in pancreatic ductal adenocarcinomas: lack of mutations in the BRAF and EGFR genes
Q37606161Molecular characteristics of colorectal serrated polyps and hyperplastic polyps: A STROBE compliant article
Q37139174Molecular pathways involved in colorectal cancer: implications for disease behavior and prevention
Q61958838Molecular patterns in the evolution of serrated lesion of the colorectum
Q35819037My approach to serrated polyps of the colorectum
Q37267219Nomenclature, molecular genetics and clinical significance of the precursor lesions in the serrated polyp pathway of colorectal carcinoma.
Q54497124Over-expression of cathepsin E and trefoil factor 1 in sessile serrated adenomas of the colorectum identified by gene expression analysis.
Q35965705Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics
Q39453559Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment
Q35095334RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers
Q36002845Raf kinases: function, regulation and role in human cancer
Q51975603Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer.
Q36800212Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer from cancer.
Q26827208Serrated lesions of the colorectum: review and recommendations from an expert panel
Q34005349Serrated neoplasia of the colorectum
Q38473801Serrated neoplasia-role in colorectal carcinogenesis and clinical implications
Q38015332Serrated polyposis syndrome: molecular, pathological and clinical aspects
Q24623224Serrated polyposis: an enigmatic model of colorectal cancer predisposition
Q33628909Serrated polyps of the colon and rectum (hyperplastic polyps, sessile serrated adenomas, traditional serrated adenomas, and mixed polyps)-proposal for diagnostic criteria
Q80196417Serrated polyps of the colorectum: is sessile serrated adenoma distinguishable from hyperplastic polyp in a daily practice?
Q36230771Sessile serrated adenoma shares similar genetic and epigenetic features with microsatellite unstable colon cancer in a location-dependent manner
Q36693976Sessile serrated adenomas: high-risk lesions?
Q36221351Significance of serrated polyps of the colon
Q26795609Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance
Q38239612Targeting BRAF mutant metastatic colorectal cancer: clinical implications and emerging therapeutic strategies
Q40154931Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.
Q37172151The genomics of colorectal cancer: state of the art.
Q26738611The molecular characteristics of colonic neoplasms in serrated polyposis: a systematic review and meta-analysis
Q53619358Tracing origin of serrated adenomas with BRAF and KRAS mutations.
Q33722761Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis
Q42059658V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a

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