| P2093 | author name string | Thomas Martin | |
| | Young Joon Kim | |
| | Keith Kirkwood | |
| | Stelios T. Andreadis | |
| P2860 | cites work | A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation | Q27860824 |
| | Excessive matrix metalloproteinase activity in diabetes: inhibition by tetracycline analogues with zinc reactivity | Q28199902 |
| | Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis | Q28202653 |
| | Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 |
| | How MAP kinases are regulated | Q28609360 |
| | Tetracyclines Inhibit Connective Tissue Breakdown: New Therapeutic Implications for an Old Family of Drugs | Q31034448 |
| | The p38 mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumor necrosis factor in osteoblasts | Q31881213 |
| | A combination of subtherapeutic doses of chemically modified doxycycline (CMT-8) and a bisphosphonate (clodronate) inhibits bone loss in the ovariectomized rat: a dynamic histomorphometric and gene expression study | Q31922998 |
| | p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials | Q33716182 |
| | Inhibition of p38 MAP kinase as a therapeutic strategy | Q33957191 |
| | Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements | Q34364003 |
| | Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators | Q34526913 |
| | Cytokines in rheumatoid arthritis | Q34637317 |
| | The role of cytokines and their inhibitors in arthritis | Q35233166 |
| | Signal transduction via the MAP kinases: proceed at your own RSK. | Q36381460 |
| | Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria | Q36383313 |
| | mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation | Q36555520 |
| | Immediate-early MEK-1-dependent stabilization of rat smooth muscle cell cyclooxygenase-2 mRNA by Galpha(q)-coupled receptor signaling | Q38312174 |
| | Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor | Q39122217 |
| | Biochemical Characterization with Parathormone and Calcitonin of Isolated Bone Cells: Provisional Identification of Osteoclasts and Osteoblasts | Q40007256 |
| | Messenger RNA degradation in eukaryotes | Q40489005 |
| | Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors | Q40715828 |
| | MAP kinase kinase kinase, MAP kinase kinase and MAP kinase | Q40757575 |
| | Anti-inflammatory effects of chemically modified tetracyclines by the inhibition of nitric oxide and interleukin-12 synthesis in J774 cell line. | Q40779969 |
| | Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs. | Q40864537 |
| | Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation. | Q40876856 |
| | IL-1 beta increases type 1 inositol trisphosphate receptor expression and IL-6 secretory capacity in osteoblastic cell cultures | Q40885039 |
| | Mitogen-activated protein (MAP) kinases are involved in interleukin-1 (IL-1)-induced IL-6 synthesis in osteoblasts: modulation not of p38 MAP kinase, but of p42/p44 MAP kinase by IL-1-activated protein kinase C. | Q40920971 |
| | Tetracycline derivative CMT-3 inhibits cytokine production, degranulation, and proliferation in cultured mouse and human mast cells | Q40940422 |
| | Role of cytokines in bone resorption | Q40957399 |
| | Inositol trisphosphate receptor gene expression and hormonal regulation in osteoblast-like cell lines and primary osteoblastic cell cultures | Q41148392 |
| | A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity | Q41372816 |
| | The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. | Q41850515 |
| | Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential | Q42472805 |
| | Cloning and characterization of the type I inositol 1,4,5-trisphosphate receptor gene promoter. Regulation by 17beta-estradiol in osteoblasts | Q42573504 |
| | Non-antimicrobial and antimicrobial tetracyclines inhibit IL-6 expression in murine osteoblasts | Q42813033 |
| | Stimulation of interleukin-6 promoter by parathyroid hormone, tumor necrosis factor alpha, and interleukin-1beta in UMR-106 osteoblastic cells is inhibited by protein kinase C antagonists | Q43671895 |
| | IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators | Q43845883 |
| | Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines | Q44081826 |
| | Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: regulation by interleukin-1. | Q44764247 |
| | Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation | Q45041216 |
| | A chemically modified tetracycline inhibits streptozotocin-induced diabetic depression of skin collagen synthesis and steady-state type I procollagen mRNA. | Q48027234 |
| | Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. | Q52144027 |
| | Characterization of the transcription products of glyceraldehyde 3-phosphate-dehydrogenase gene in HeLa cells | Q70671882 |
| | Leukaemia inhibitory factor stimulates proteoglycan resorption in porcine articular cartilage | Q70774525 |
| | Chemically modified tetracyclines inhibit inducible nitric oxide synthase expression and nitric oxide production in cultured rat mesangial cells | Q71857936 |
| | Tetracycline/flurbiprofen combination therapy modulates bone remodeling in ovariectomized rats: preliminary observations | Q71899888 |
| | Tetracyclines inhibit Porphyromonas gingivalis-induced alveolar bone loss in rats by a non-antimicrobial mechanism | Q72730731 |
| | Doxycycline and chemically modified tetracyclines inhibit gelatinase A (MMP-2) gene expression in human skin keratinocytes | Q72852972 |
| | Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines | Q73545387 |
| | Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis | Q73684776 |
| | In vitro sensitivity of the three mammalian collagenases to tetracycline inhibition: relationship to bone and cartilage degradation | Q74071849 |
| | Chemically modified non-antimicrobial tetracyclines inhibit activity of phospholipases A2 | Q77228038 |
| | Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase | Q77229202 |
| | Pharmacologic suppression of experimental abdominal aortic aneurysms: acomparison of doxycycline and four chemically modified tetracyclines | Q77655778 |
| | The influence of serum cytokines and growth factors on osteoclast formation in Paget's disease | Q77892870 |
| | Treatment of osteoporosis with MMP inhibitors | Q78027247 |
| | Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms | Q78106043 |
| | Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells | Q78106097 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | biochemistry | Q7094 |
| | pharmacology | Q128406 |
| | tetracycline | Q193045 |
| | osteoblast | Q917177 |
| P304 | page(s) | 1809-1819 | |
| P577 | publication date | 2003-11-01 | |
| P1433 | published in | Biochemical Pharmacology | Q864229 |
| P1476 | title | Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability | |
| P478 | volume | 66 | |