The Pro12Ala and C-681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren

scientific article published on 9 July 2005

The Pro12Ala and C-681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00125-005-1817-0
P698PubMed publication ID16007414
P5875ResearchGate publication ID237906680

P50authorColin PalmerQ42603882
Alexander S DoneyQ57327614
Marion M. HetheringtonQ47203061
P2093author name stringP Watt
B Fischer
C Bolton-Smith
J E Cecil
W Wrieden
P2860cites workThe common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetesQ24290189
Establishing a standard definition for child overweight and obesity worldwide: international surveyQ24643889
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?Q24685208
Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locusQ24791858
Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.Q24799062
A New Statistical Method for Haplotype Reconstruction from Population DataQ27860495
PPARgamma, the ultimate thrifty geneQ33711175
Alanine for proline substitution in the peroxisome proliferator-activated receptor gamma-2 (PPARG2) gene and the risk of incident myocardial infarctionQ34509923
Body mass index reference curves for the UK, 1990Q34796304
Cross sectional stature and weight reference curves for the UK, 1990Q34796371
C/EBPalpha induces adipogenesis through PPARgamma: a unified pathwayQ35004645
Prevalence and trends in overweight and obesity in three cross sectional studies of British Children, 1974-94.Q37139137
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivityQ38331543
2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysisQ47209999
The 161TT genotype in the exon 6 of the peroxisome-proliferator-activated receptor gamma gene is associated with premature acute myocardial infarction and increased lipid peroxidation in habitual heavy smokersQ47292130
Prevalence of overweight among children in EuropeQ47358659
The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthoodQ47428293
Peroxisome proliferator-activated receptor-gammaPro12Ala polymorphism and the association with blood pressure in type 2 diabetes: skaraborg hypertension and diabetes project.Q50724144
Evidence for gene-nutrient interaction at the PPARgamma locus.Q51550350
A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humansQ57606060
Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to Type 2 diabetesQ57639011
Increasing levels of excess weight among children in EnglandQ58463792
Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese womenQ73086825
Peroxisome proliferator-activated receptor gamma C161-->T polymorphism and coronary artery diseaseQ73482789
A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophyQ43853009
PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophyQ44230983
A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French populationQ44316929
The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study.Q44358377
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gammaQ44381179
CHO intake alters obesity risk associated with Pro12Ala polymorphism of PPARgamma geneQ44439174
Peroxisome proliferator-activated receptor-gamma2-Pro12Ala and endothelial nitric oxide synthase-4a/bgene polymorphisms are associated with essential hypertensionQ44552286
Interaction between a peroxisome proliferator-activated receptor gene polymorphism and dietary fat intake in relation to body massQ44594023
Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?Q44697559
Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone actionQ44962108
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS studyQ45108289
Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutationQ46671380
P433issue8
P304page(s)1496-1502
P577publication date2005-07-09
P1433published inDiabetologiaQ5270140
P1476titleThe Pro12Ala and C-681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren
P478volume48

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cites work (P2860)
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Q28283856Association of the CYBA, PPARGC1A, PPARG3, and PPARD gene variants with coronary artery disease and metabolic risk factors of coronary atherosclerosis in a Russian population
Q39258427Association of the peroxisome proliferator-activated receptor-gamma2 Pro12Ala but not the C1431T gene variants with lower body mass index in Type 2 diabetes
Q34024302BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1
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Q50100048Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS).
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Q57638983PPARG Locus Haplotype Variation and Exacerbations in Asthma
Q45960080PPARG genotype accounts for part of individual variation in body weight reduction in response to calorie restriction.
Q36063081PPARgamma in human and mouse physiology
Q51490514Patterns of association between PPARgamma genetic variation and indices of adiposity and insulin action in African-Americans and whites: the CARDIA Study.
Q54231445Polymorphisms in LEPR, PPARG and APM1 genes: associations with energy intake and metabolic traits in young children.
Q50665108Two Novel SNPs of PPARγ Significantly Affect Weaning Growth Traits of Nanyang Cattle.

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