Analysis of rotavirus non-structural protein NSP5 by mass spectrometry reveals a complex phosphorylation pattern

scientific article published on 28 December 2009

Analysis of rotavirus non-structural protein NSP5 by mass spectrometry reveals a complex phosphorylation pattern is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIRUSRES.2009.12.006
P698PubMed publication ID20036292
P5875ResearchGate publication ID40785046

P2093author name stringEberhard Krause
Michael Schümann
Jonas Chnaiderman
Pablo H Sotelo
P2860cites workA protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold unitsQ27764581
Two non-structural rotavirus proteins, NSP2 and NSP5, form viroplasm-like structures in vivoQ28138600
Rotavirus NSP5 phosphorylation is up-regulated by interaction with NSP2Q28289075
Phosphorylation generates different forms of rotavirus NSP5Q28290121
Characterization by tandem mass spectrometry of structural modifications in proteinsQ28295440
JPred: a consensus secondary structure prediction serverQ29614378
Analysis of autophosphorylation sites in the recombinant catalytic subunit alpha of cAMP-dependent kinase by nano-UPLC-ESI-MS/MS.Q30378806
Accessibility of cysteines in the native bovine rod cGMP-gated channelQ31144945
State-of-the-art in phosphoproteomicsQ33224302
Nalpha -terminal acetylation of eukaryotic proteinsQ34050317
Global Illness and Deaths Caused by Rotavirus Disease in ChildrenQ34275969
RNA-binding activity of the rotavirus phosphoprotein NSP5 includes affinity for double-stranded RNA.Q34338593
Cryoelectron microscopy structures of rotavirus NSP2-NSP5 and NSP2-RNA complexes: implications for genome replication.Q35139285
The formation of viroplasm-like structures by the rotavirus NSP5 protein is calcium regulated and directed by a C-terminal helical domainQ36315068
The CXXC motif at the N terminus of an alpha-helical peptideQ36458569
An ATPase activity associated with the rotavirus phosphoprotein NSP5.Q37242950
Uncoupling substrate and activation functions of rotavirus NSP5: phosphorylation of Ser-67 by casein kinase 1 is essential for hyperphosphorylationQ37621756
Analysis of rotavirus nonstructural protein NSP5 phosphorylationQ39579345
Rotavirus NSP5: mapping phosphorylation sites and kinase activation and viroplasm localization domainsQ39682944
Hyperphosphorylation of the rotavirus NSP5 protein is independent of serine 67, [corrected] NSP2, or [corrected] the intrinsic insolubility of NSP5 is regulated by cellular phosphatasesQ40324521
The C-terminal domain of rotavirus NSP5 is essential for its multimerization, hyperphosphorylation and interaction with NSP6.Q40899934
The CXXC motif: imperatives for the formation of native disulfide bonds in the cell.Q41065191
Characterization of rotavirus replication intermediates: a model for the assembly of single-shelled particles.Q41272924
Impaired hyperphosphorylation of rotavirus NSP5 in cells depleted of casein kinase 1alpha is associated with the formation of viroplasms with altered morphology and a moderate decrease in virus replicationQ45400066
The CXXC motif: a rheostat in the active site.Q52267222
Rotavirus NS26 is modified by addition of single O-linked residues of N-acetylglucosamineQ54697549
The genetics of disulfide bond metabolismQ77936221
NSP5 phosphorylation regulates the fate of viral mRNA in rotavirus infected cellsQ78363918
P4510describes a project that usesmass spectrometryQ180809
Simian rotavirus A/SA11-4FQ112242692
P433issue1
P921main subjectRotavirusQ164778
post-translational protein modificationQ898362
Rotavirus A/C, non-structural protein 5Q24739451
P304page(s)104-108
P577publication date2009-12-28
P1433published inVirus ResearchQ15749215
P1476titleAnalysis of rotavirus non-structural protein NSP5 by mass spectrometry reveals a complex phosphorylation pattern
P478volume149

Reverse relations

cites work (P2860)
Q41909023A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly
Q92503104Conserved Rotavirus NSP5 and VP2 Domains Interact and Affect Viroplasm
Q54209639Cytoplasmic re-localization and colocalization with viroplasms of host cell proteins, and their role in rotavirus infection.
Q113878572Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses
Q89761656MicroRNA-7 Inhibits Rotavirus Replication by Targeting Viral NSP5 In Vivo and In Vitro
Q51867016Molecular characterization of the porcine group A rotavirus NSP2 and NSP5/6 genes from São Paulo State, Brazil, in 2011/12.
Q30815323New tags for recombinant protein detection and O-glycosylation reporters
Q90753669Recombinant Rotaviruses Rescued by Reverse Genetics Reveal the Role of NSP5 Hyperphosphorylation in the Assembly of Viral Factories
Q114123068Recombinant rotaviruses rescued by reverse genetics reveal the role of NSP5 hyperphosphorylation in the assembly of viral factories
Q57149434Rotavirus Induces Formation of Remodeled Stress Granules and P Bodies and Their Sequestration in Viroplasms To Promote Progeny Virus Production.
Q114370944Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
Q36407402Rotavirus replication is correlated with S/G2 interphase arrest of the host cell cycle

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