Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms

scientific article published in December 2003

Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1196/ANNALS.1281.025
P698PubMed publication ID14751837

P50authorRuiwen ZhangQ29887890
Hui WangQ86913613
P2093author name stringZhuo Zhang
Sudhir Agrawal
Patsy Oliver
P2860cites workThe ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexesQ24608783
Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.Q36080896
mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell lineQ36138865
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agentsQ36761728
Pharmacology of Therapeutic OligonucleotidesQ38345416
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor proteinQ40018842
Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiationQ40836669
Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma.Q55024311
In VivoPharmacokinetics of Phosphorothioate Oligonucleotides Containing Contiguous GuanosinesQ73488159
P407language of work or nameEnglishQ1860
P304page(s)217-235
P577publication date2003-12-01
P1433published inAnnals of the New York Academy of SciencesQ2431664
P1476titleChemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms
P478volume1002

Reverse relations

cites work (P2860)
Q57115778Advanced Glycation End Products Increase MDM2 Expression via Transcription Factor KLF5
Q37189998Antisense, RNAi, and gene silencing strategies for therapy: mission possible or impossible?
Q37389892Antisense-MDM2 sensitizes LNCaP prostate cancer cells to androgen deprivation, radiation, and the combination in vivo
Q36458427Antisense-based cancer therapeutics: are we there yet?
Q24299167Daxx is reciprocally regulated by Mdm2 and Hausp
Q39875059FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.
Q33880170Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs
Q35925611Gene therapy strategies to improve the effectiveness of cancer radiotherapy
Q92030437Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer
Q33480331Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects?
Q36689088Radiation and SN38 treatments modulate the expression of microRNAs, cytokines and chemokines in colon cancer cells in a p53-directed manner
Q37524156Recent advances in validating MDM2 as a cancer target.
Q36710840Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.
Q40392451Signaling via the anti-CD30 mAb SGN-30 sensitizes Hodgkin's disease cells to conventional chemotherapeutics
Q38320884Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway
Q35030217Targeting MDM2-p53 interaction for cancer therapy: are we there yet?
Q37081504The use of p53 as a tool for human cancer therapy
Q33927539Uric acid protects against secondary damage after spinal cord injury

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