scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M400646200 |
P8608 | Fatcat ID | release_vdjf6zf5i5fxjkil6sstdnptyy |
P698 | PubMed publication ID | 14766742 |
P2093 | author name string | Gregorio Gil | |
William M Pandak | |||
Antonio del Castillo-Olivares | |||
José A Campos | |||
P2860 | cites work | Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns | Q22008833 |
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors | Q24290397 | ||
The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression | Q24554362 | ||
CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene | Q24654020 | ||
A unified nomenclature system for the nuclear receptor superfamily | Q28142509 | ||
The enzymes, regulation, and genetics of bile acid synthesis | Q28204726 | ||
Alpha 1-fetoprotein transcription factor is required for the expression of sterol 12alpha -hydroxylase, the specific enzyme for cholic acid synthesis. Potential role in the bile acid-mediated regulation of gene transcription | Q28375187 | ||
Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter | Q28513496 | ||
The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family | Q28571516 | ||
Differential expression of steroidogenic factor-1 and FTF/LRH-1 in the rodent ovary | Q28579504 | ||
On the mechanism of bile acid inhibition of rat sterol 12α-hydroxylase gene (CYP8B1) transcription: roles of α-fetoprotein transcription factor and hepatocyte nuclear factor 4α | Q29032141 | ||
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery | Q29615235 | ||
A receptor-mediated pathway for cholesterol homeostasis | Q29616158 | ||
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis | Q29617241 | ||
The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the Hnf3beta, Hnf4alpha, and Hnf1alpha gene promoters | Q30644800 | ||
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis | Q33566678 | ||
Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription | Q33786733 | ||
The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor | Q33944953 | ||
Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression | Q34089245 | ||
Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I. | Q34198844 | ||
Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice. | Q36651232 | ||
Structure of the mouse cholesterol 7 alpha-hydroxylase gene | Q36740472 | ||
c-Myc target gene specificity is determined by a post-DNAbinding mechanism | Q36808429 | ||
Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter | Q38293980 | ||
Coexamination of site-specific transcription factor binding and promoter activity in living cells | Q39449417 | ||
Activation of the promoter of the orphan receptor SHP by orphan receptors that bind DNA as monomers | Q40941501 | ||
Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter | Q42511033 | ||
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway | Q43559873 | ||
The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by | Q43636951 | ||
Redundant pathways for negative feedback regulation of bile acid production | Q44025689 | ||
Suppression of cholesterol 7alpha-hydroxylase transcription and bile acid synthesis by an alpha1-antitrypsin peptide via interaction with alpha1-fetoprotein transcription factor | Q44132516 | ||
Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes | Q44170609 | ||
Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle | Q44514694 | ||
Regulation of sterol 12alpha-hydroxylase and cholic acid biosynthesis in the rat. | Q44869232 | ||
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. | Q45108263 | ||
P433 | issue | 16 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 16813-16821 | |
P577 | publication date | 2004-02-06 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | The role of alpha1-fetoprotein transcription factor/LRH-1 in bile acid biosynthesis: a known nuclear receptor activator that can act as a suppressor of bile acid biosynthesis | |
P478 | volume | 279 |
Q24305147 | A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene |
Q35795688 | Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expression |
Q34540006 | All-trans retinoic acid regulates hepatic bile acid homeostasis |
Q42704943 | Bile acid flux through portal but not peripheral veins inhibits CYP7A1 expression without involvement of ileal FGF19 in rabbits |
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Q24293122 | Functional conservation of interactions between a homeodomain cofactor and a mammalian FTZ-F1 homologue |
Q38520051 | Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype |
Q36983521 | Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27. |
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Q35148501 | Identification of transcription factors and single nucleotide polymorphisms of Lrh1 and its homologous genes in Lrh1-knockout pancreas of mice |
Q51757951 | Impaired progesterone production in Nr5a2+/- mice leads to a reduction in female reproductive function. |
Q40174330 | Interaction between sterol regulatory element-binding proteins and liver receptor homolog-1 reciprocally suppresses their transcriptional activities |
Q57121222 | Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration |
Q36693487 | Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. |
Q59797226 | Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases |
Q36445376 | Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation |
Q38626000 | Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes. |
Q28587194 | Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development |
Q40324625 | Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation |
Q34692881 | Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription |
Q37121662 | Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. |
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Q46952925 | The stimulatory effect of LXRalpha is blocked by SHP despite the presence of a LXRalpha binding site in the rabbit CYP7A1 promoter |
Q33678751 | alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator |
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