Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation

scientific article published in February 2004

Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.0906-6705.2004.00119.X
P698PubMed publication ID15009100
P5875ResearchGate publication ID5613386

P50authorMark R PittelkowQ87725759
P2093author name stringAlexander Meves
Dominik Peus
Mariuca Vasa
Astrid Beyerle
Markus Pott
P2860cites workDifferential responses of S100A2 to oxidative stress and increased intracellular calcium in normal, immortalized, and malignant human keratinocytesQ34160220
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosisQ36571893
Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylationQ36842018
Coenzyme Q10, plasma membrane oxidase and growth control.Q40526879
Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptorQ41382176
Antipsoriatic and proinflammatory action of anthralin. Implications for the role of oxygen radicalsQ41523921
DithranolQ41603208
Oxygen radicals and signalingQ41750986
H(2)O(2) mediates oxidative stress-induced epidermal growth factor receptor phosphorylationQ43698438
Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytesQ44224867
Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptorsQ46175993
H2O2 is an important mediator of UVB-induced EGF-receptor phosphorylation in cultured keratinocytesQ47993793
Anti-Psoriatic Drug Anthralin Activates JNK via Lipid Peroxidation: Mononuclear Cells are More Sensitive than KeratinocytesQ60683374
Inactivation of mouse epidermal 12-lipoxygenase by anthralin--implications for the role of oxygen radicalsQ71113675
Effects of anthralin and hypericin on growth factor signalling and cell proliferation in vitroQ71634678
Inhibition of dithranol inflammation by free-radical scavengersQ72593357
A highly sensitive fluorescent micro-assay of H2O2 release from activated human leukocytes using a dihydroxyphenoxazine derivativeQ73233442
Protein tyrosine kinase activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos and c-jun expressionQ73253955
H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activationQ73370504
PsoriasisQ73574043
UVB-induced epidermal growth factor receptor phosphorylation is critical for downstream signaling and keratinocyte survivalQ74057136
UVB activates ERK1/2 and p38 signaling pathways via reactive oxygen species in cultured keratinocytesQ77419399
P433issue2
P921main subjectphosphorylationQ242736
keratinocyteQ1473931
P304page(s)78-85
P577publication date2004-02-01
P1433published inExperimental DermatologyQ15749509
P1476titleAntipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation
P478volume13

Reverse relations

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Q37327907Design, synthesis and in vitro degradation of a novel co-drug for the treatment of psoriasis.
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Q33936025Hydrogen peroxide generated extracellularly by receptor-ligand interaction facilitates cell signaling
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Q24799882Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation
Q34076696Targeted 307 nm UVB-phototherapy in psoriasis. A pilot study comparing a 307 nm excimer light with topical dithranol
Q42876205Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining
Q36780173What is a role of haeme oxygenase-1 in psoriasis? Current concepts of pathogenesis
Q82066613[Mechanisms and treatment of psoriasis]

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