The C-532T polymorphism of the angiotensinogen gene is associated with pulse pressure: a possible explanation for heterogeneity in genetic association studies of AGT and hypertension

scientific article published on 12 November 2007

The C-532T polymorphism of the angiotensinogen gene is associated with pulse pressure: a possible explanation for heterogeneity in genetic association studies of AGT and hypertension is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/IJE/DYM213
P8608Fatcat IDrelease_jizvbczqvvanlnbysqyu4kauz4
P698PubMed publication ID17998241
P5875ResearchGate publication ID5849168

P50authorHugh Christian WatkinsQ5930325
Bongani MayosiQ17626836
Martin FarrallQ28050051
Darroch HallQ42441189
Bernard KeavneyQ64858562
Thahira RahmanQ117252545
P2093author name stringJohn M C Connell
Peter J Avery
Michelle Baker
P2860cites work‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*Q22066036
Polymorphisms of the insertion / deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of dataQ24793038
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Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studiesQ28036762
PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping dataQ30991765
A general test of association for quantitative traits in nuclear familiesQ34146162
Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysisQ34205648
Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.Q34497859
Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal.Q41665134
Insulin and insulin-like growth factor-I promotes angiotensinogen production and growth in vascular smooth muscle cellsQ41757255
Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertensionQ43984486
Angiotensinogen gene and essential hypertension in the Japanese: extensive association study and meta-analysis on six reported studiesQ44745690
Molecular basis of human hypertension: role of angiotensinogenQ45118696
Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood InstituteQ46336499
Association between common polymorphisms of the proopiomelanocortin gene and body fat distribution: a family study.Q46620692
Biological and environmental sources of familial aggregation of blood pressure: the Jerusalem Lipid Research ClinicQ47382628
Genetic variance in blood pressureQ52859427
M235T angiotensinogen gene polymorphism and cardiovascular renal risk.Q52910086
Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure.Q52991970
Chromosome-wide distribution of haplotype blocks and the role of recombination hot spotsQ56879657
Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysisQ56893651
Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive proteinQ57200477
Vascular injury induces angiotensinogen gene expression in the media and neointimaQ58364012
P433issue6
P304page(s)1356-1362
P577publication date2007-11-12
P1433published inInternational Journal of EpidemiologyQ6051393
P1476titleThe C-532T polymorphism of the angiotensinogen gene is associated with pulse pressure: a possible explanation for heterogeneity in genetic association studies of AGT and hypertension
P478volume36

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cites work (P2860)
Q26825571A review of genetics, arterial stiffness, and blood pressure in African Americans.
Q34997022Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals
Q35555945Association of self-reported race/ethnicity and genetic ancestry with arterial elasticity: the Multi-Ethnic Study of Atherosclerosis (MESA)
Q37677152Endothelial dysfunction in experimental models of arterial hypertension: cause or consequence?
Q37678564Gene variants of the renin-angiotensin system and hypertension: from a trough of disillusionment to a welcome phase of enlightenment?
Q33879230Genetic and environmental risks for high blood pressure among African American mothers and daughters
Q30301168Genetic determinants of arterial stiffness
Q46173570Genetics of human hypertension, the role of angiotensinogen. should it be one of the drug target genes?
Q64959338Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness.
Q41454395Synergistic effects of gene polymorphisms of the renin-angiotensin-aldosterone system on essential hypertension in Kazakhs in Xinjiang

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