| P2093 | author name string | M E Veronese | |
| | S McLean | |
| P2860 | cites work | Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines | Q24339615 |
| | Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15 | Q28302901 |
| | Kinetic Evidence for Multiple Chemically Reactive Intermediates in the Breakdown of Phenacetin N-O-Glucuronide | Q28329252 |
| | Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450 | Q28334864 |
| | Characterization of the common genetic defect in humans deficient in debrisoquine metabolism | Q34049056 |
| | Polymorphic hydroxylation of Debrisoquine in man. | Q34057031 |
| | A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking | Q34418056 |
| | Phenacetin O-deethylase: an activity of a cytochrome P-450 showing genetic linkage with that catalysing the 4-hydroxylation of debrisoquine? | Q34446534 |
| | Debrisoquine oxidation in an Australian population | Q34447633 |
| | Inter-subject and ethnic differences in paracetamol metabolism | Q34448179 |
| | The contribution of genetically determined oxidation status to inter-individual variation in phenacetin disposition | Q34513027 |
| | Influence of sex and oral contraceptive steroids on paracetamol metabolism | Q34513321 |
| | Reactive metabolites of phenacetin and acetaminophen: a review | Q35037087 |
| | Genetics of drug transformation | Q39733561 |
| | Neoplasia in the rat induced by N-Hydroxyphenacetin, a metabolite of phenacetin | Q40016626 |
| | Effects of nutritive factors on metabolic processes involving bioactivation and detoxication of chemicals | Q40184046 |
| | Inherited defects of hepatic drug metabolism | Q40209889 |
| | Clinical pharmacokinetics of paracetamol | Q40327661 |
| | Generation of reactive metabolites of N-hydroxy-phenacetin by glucuronidation and sulfation | Q41234848 |
| | Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors | Q41463151 |
| | Some observations on the oxidation phenotype status of Nigerian patients presenting with cancer | Q41639246 |
| | Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver | Q41883910 |
| | The metabolism of N-hydroxyphenacetin in vitro and in vivo | Q42229994 |
| | N-hydroxyphenacetin, a new urinary metabolite of phenacetin in the rat | Q42241237 |
| | Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices | Q42250442 |
| | Polymorphic drug oxidation in humans | Q42255882 |
| | The metabolism of acetophenetidine. Isolation and characterization of S-(1-acetamido-4-hydroxyphenyl)-cysteine, a metabolite of acetophenetidine | Q42965019 |
| | Comparative activation of paracetamol in the rat, mouse and man. | Q43599061 |
| | The comparative metabolism of phenacetin and N-acetyl-p-aminophenol in man, with particular reference to effects on the kidney | Q44417952 |
| | Formation of reactive metabolites of phenacetin in humans and rats | Q44956730 |
| | Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells. | Q45184367 |
| | Conversion of the N-Q-glucuronide and N-O-sulfate conjugates of N-hydroxyphenacetin to reactive intermediates. | Q45992824 |
| | Factors affecting the metabolism of phenacetin. I. Influence of dose, chronic dosage, route of administration and species on the metabolism of (1-14C-acetyl)phenacetin | Q46684482 |
| | Species variation in toxication and detoxication of acetaminophen in vivo: a comparative study of biliary and urinary excretion of acetaminophen metabolites. | Q46728740 |
| | Temporal variations in acetaminophen and phenacetin half-life in man | Q46732044 |
| | Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions | Q47777194 |
| | Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation. | Q50216063 |
| | Metabolic characterization of human liver microsomal cytochromes P-450 involved in the oxidation of debrisoquine, bufuralol and the carcinogen 2-acetylaminofluorene. | Q52456386 |
| | On the pharmacokinetics of phenacetin in man | Q52879375 |
| | Species differences in the hepatotoxicity of paracetamol are due to differences in the rate of conversion to its cytotoxic metabolite. | Q54409047 |
| | Lung cancer risk, occupational exposure, and the debrisoquine metabolic phenotype | Q58047534 |
| | Polymorphism of carbon oxidation of drugs and clinical implications | Q66841868 |
| | Hypotensive response to debrisoquine and hydroxylation phenotype | Q67320003 |
| | Debrisoquine oxidation polymorphism in a Tasmanian population | Q67963187 |
| | An introduction to metabolic and kinetic aspects of toxicological studies | Q68271592 |
| | Inhibition of DNA, RNA and protein synthesis and chromatin alteration by N-hydroxyphenacetin | Q68986978 |
| | Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2 | Q69624974 |
| | Effect of aspirin, caffeine, and codeine on the metabolism of phenacetin and acetaminophen | Q70502871 |
| | Mass spectrometric determination of N-hydroxyphenacetin in urine using multiple metastable peak monitoring following thin-layer chromatography | Q70676334 |
| | Formation and disposition of the minor metabolites of acetaminophen in the hamster | Q72486598 |
| | Acetophenetidin-induced methemoglobinemia and its relation to the excretion of diazotizable amines | Q72532238 |
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | paracetamol | Q57055 |
| P304 | page(s) | 547-552 | |
| P577 | publication date | 1991-01-01 | |
| P1433 | published in | European Journal of Clinical Pharmacology | Q1376707 |
| P1476 | title | Metabolism of paracetamol and phenacetin in relation to debrisoquine oxidation phenotype | |
| P478 | volume | 40 | |