CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid

scientific article

CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CEI.12032
P932PMC publication ID3719926
P698PubMed publication ID23480180
P5875ResearchGate publication ID236036540

P50authorGeorge NotasQ42462647
George KoliosQ42462669
P2093author name stringE Kouroumalis
I Drygiannakis
P Manousou
A Voumvouraki
H A Papadaki
K Pyrovolaki
L Bourikas
M Koulentaki
P2860cites workChemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liverQ22010826
Ursodeoxycholic acid reduces increased circulating endothelin 2 in primary biliary cirrhosisQ24293659
An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4Q24303828
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytesQ24336187
Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cellsQ24563090
Expression of functional CXCR4 chemokine receptors on human colonic epithelial cellsQ24563114
Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3Q24647146
Mig and IP-10: CXC chemokines that target lymphocytesQ28305342
Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitisQ30437183
Recruitment of lymphocytes to the human liver.Q34116247
The role of chemokines in the immunopathology of the liverQ34118835
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisitedQ34146325
Primary biliary cirrhosis: what we know and what we want to know about human PBC and spontaneous PBC mouse modelsQ36767562
Lymphocyte recruitment to the liver: molecular insights into the pathogenesis of liver injury and hepatitisQ37087991
CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liverQ37714863
Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)Q39859200
Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines.Q39951498
Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skippingQ40495285
Active participation of CCR5(+)CD8(+) T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease.Q40851124
Ciprofloxacin inhibits cytokine-induced nitric oxide production in human colonic epithelium.Q42501287
The role of CCR5/CXCR3 expressing CD8+ cells in liver damage and viral control during persistent hepatitis C virus infectionQ42513891
Pathogenesis of primary biliary cirrhosis: a unifying modelQ42726334
CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivationQ42836727
Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis.Q45952178
Increased levels of chemokine receptor CXCR3 and chemokines IP-10 and MIG in patients with primary biliary cirrhosis and their first degree relativesQ46700450
The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig.Q52039719
Anti-interferon-inducible chemokine, CXCL10, reduces colitis by impairing T helper-1 induction and recruitment in mice.Q53660265
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.Q54380949
Activated T-lymphocytes with myelosuppressive properties in patients with chronic idiopathic neutropeniaQ58041641
Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human LiverQ61943219
Promotion of leukocyte transendothelial cell migration by chemokines derived from human biliary epithelial cells in vitroQ73504637
Increased cell apoptosis in bone marrow trephine biopsies and immunomagnetically isolated myeloid progenitor cells in patients with chronic idiopathic neutropeniaQ73773759
Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liverQ82612054
Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in miceQ83179770
P433issue1
P921main subjectprimary biliary cholangitisQ1072420
P304page(s)9-15
P577publication date2013-04-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleCXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid
P478volume172

Reverse relations

cites work (P2860)
Q92294041A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Q37072376Chemokine and chemokine receptors in autoimmunity: the case of primary biliary cholangitis
Q35933236Functional and structural features of cholangiocytes in health and disease
Q58732635Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9
Q55202763NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid.
Q38342107Novel therapeutic targets in primary biliary cirrhosis
Q26799419Primary biliary cirrhosis: From bench to bedside
Q27025680Review article: chemokines as orchestrators of autoimmune hepatitis and potential therapeutic targets
Q26827599Review article: permanent drug withdrawal is desirable and achievable for autoimmune hepatitis
Q50158327The molecular basis of immune regulation in autoimmunity
Q38496935Transitioning from Idiopathic to Explainable Autoimmune Hepatitis

Search more.