| scholarly article | Q13442814 |
| P50 | author | Christopher J Howe | Q70203152 |
| P2093 | author name string | R Ellen R Nisbet | |
| Petrus J de Vries | |||
| Jaco Serfontein | |||
| P2860 | cites work | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools | Q24248165 |
| The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3 | Q24294590 | ||
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive | Q24306328 | ||
| Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning | Q24320102 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway | Q24337225 | ||
| Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity | Q24563018 | ||
| Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase | Q24564747 | ||
| The TSC1-TSC2 complex: a molecular switchboard controlling cell growth | Q24645204 | ||
| Improved tools for biological sequence comparison | Q24652199 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| T-Coffee: A novel method for fast and accurate multiple sequence alignment | Q27860999 | ||
| Predicting coiled coils from protein sequences | Q27861097 | ||
| Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility. | Q27935025 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B | Q28208783 | ||
| Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin | Q28210500 | ||
| Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
| Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development | Q28508306 | ||
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway | Q28646919 | ||
| Animal models of human disease: zebrafish swim into view | Q29615723 | ||
| The tuberous sclerosis complex | Q29619128 | ||
| Akt regulates growth by directly phosphorylating Tsc2 | Q29620397 | ||
| Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism | Q30480422 | ||
| Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures. | Q31139342 | ||
| Akt phosphorylates both Tsc1 and Tsc2 in Drosophila, but neither phosphorylation is required for normal animal growth | Q33483334 | ||
| Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. | Q33756854 | ||
| The NF1 tumor suppressor critically regulates TSC2 and mTOR. | Q33841600 | ||
| Zebrafish: bridging the gap between development and disease | Q34045906 | ||
| Dysregulation of the TSC-mTOR pathway in human disease | Q34380413 | ||
| Drosophila is an inclusive model for human diseases, growth and development | Q34765407 | ||
| Aberrant beta-catenin signaling in tuberous sclerosis | Q35084861 | ||
| Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction | Q36599297 | ||
| Genetic aspects of birth defects: new understandings of old problems | Q36856368 | ||
| The tuberous sclerosis complex proteins--a GRIPP on cognition and neurodevelopment | Q36882262 | ||
| The TSC/Rheb/TOR signaling pathway in fission yeast and mammalian cells: temperature sensitive and constitutive active mutants of TOR. | Q36885333 | ||
| Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation | Q36936439 | ||
| Targeted treatments for cognitive and neurodevelopmental disorders in tuberous sclerosis complex | Q37774096 | ||
| S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade | Q39627495 | ||
| Computational approaches to identify leucine zippers | Q39723998 | ||
| Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/- mice | Q40237430 | ||
| Tsc2 is not a critical target of Akt during normal Drosophila development | Q40436043 | ||
| gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle | Q41610591 | ||
| Evolution of the TSC1/TSC2-TOR signaling pathway. | Q43001673 | ||
| Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe | Q44725308 | ||
| Behavioral measures of anxiety in zebrafish (Danio rerio). | Q48248398 | ||
| A reality check for alignments and trees | Q57179008 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | bioinformatics | Q128570 |
| P304 | page(s) | 349-356 | |
| P577 | publication date | 2011-01-18 | |
| P1433 | published in | Behavior Genetics | Q4034967 |
| P1476 | title | Conservation of structural and functional elements of TSC1 and TSC2: a bioinformatic comparison across animal models | |
| P478 | volume | 41 |
| Q40498907 | Intellectual ability in tuberous sclerosis complex correlates with predicted effects of mutations on TSC1 and TSC2 proteins |
| Q33617062 | TSC1 and TSC2 gene mutations and their implications for treatment in Tuberous Sclerosis Complex: a review |
| Q38559901 | The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control |
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