scholarly article | Q13442814 |
P50 | author | Robert A Rissman | Q88618697 |
P2093 | author name string | Wylie Vale | |
Kuo-Fen Lee | |||
Paul E Sawchenko | |||
P2860 | cites work | Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. | Q53245764 |
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation | Q56864539 | ||
The 'marginal division': a new subdivision in the neostriatum of the rat | Q69102577 | ||
Rapid reversible phosphorylation of rat brain tau proteins in response to cold water stress | Q72021460 | ||
Neuropeptide abnormalities in patients with early Alzheimer disease | Q73191849 | ||
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway | Q74277649 | ||
Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease | Q77838129 | ||
Effect of restraint and injection methods on heart rate and body temperature in mice | Q79181153 | ||
Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease | Q24303455 | ||
Neuropathological stageing of Alzheimer-related changes | Q27860862 | ||
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration | Q28140796 | ||
Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists | Q28214775 | ||
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17 | Q28274687 | ||
Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules | Q28282209 | ||
Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development | Q28512911 | ||
Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I | Q28581533 | ||
The renaissance of GSK3 | Q29616725 | ||
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease | Q29617286 | ||
Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin | Q29617507 | ||
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy | Q30479525 | ||
Circuits and mechanisms governing hypothalamic responses to stress: a tale of two paradigms | Q33875313 | ||
Hippocampal corticotropin releasing hormone: pre- and postsynaptic location and release by stress | Q34072557 | ||
The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. | Q34182381 | ||
Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression | Q34303585 | ||
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation | Q34409048 | ||
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. | Q34471162 | ||
CRF signaling: molecular specificity for drug targeting in the CNS. | Q34560821 | ||
Mapping brain response to social stress in rodents with c-fos expression: a review | Q34780577 | ||
Role of CRH in the pathogenesis of dementia of Alzheimer's type and other dementias. | Q35023154 | ||
Developmentally regulated expression of specific tau sequences | Q35545934 | ||
CRF and CRF receptors: role in stress responsivity and other behaviors | Q35639182 | ||
MARKing tau for tangles and toxicity. | Q35902808 | ||
Development neurobiology of the stress response: multilevel regulation of corticotropin-releasing hormone function | Q36102956 | ||
The stress system in the human brain in depression and neurodegeneration | Q36183541 | ||
The neuroprotective actions of corticotropin releasing hormone | Q36208339 | ||
The molecular mechanisms underlying the regulation of the biological activity of corticotropin-releasing hormone receptors: implications for physiology and pathophysiology. | Q36399313 | ||
Remodeling of neuronal networks by stress | Q36486657 | ||
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia | Q36507684 | ||
Stress-induced tau phosphorylation in mouse strains with different brain Erk 1 + 2 immunoreactivity | Q38331253 | ||
Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition | Q38582618 | ||
Paired helical filaments associated with Alzheimer disease are readily soluble structures | Q38596590 | ||
Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease. | Q40237749 | ||
The impact of physiological stimuli on the expression of corticotropin-releasing hormone (CRH) and other neuropeptide genes | Q40935061 | ||
Autoregulation of protein phosphatase type 2A expression | Q41024570 | ||
The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress | Q41091502 | ||
Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis | Q41344771 | ||
Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease | Q41358685 | ||
Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging | Q41498705 | ||
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state | Q41525580 | ||
Do centrally administered neuropeptides access cognate receptors?: an analysis in the central corticotropin-releasing factor system. | Q41716357 | ||
Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. | Q41727428 | ||
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress | Q41830251 | ||
Use of telemetry to record body temperature and activity in mice | Q41889952 | ||
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. | Q42141352 | ||
Tau is a candidate gene for chromosome 17 frontotemporal dementia | Q42456776 | ||
Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease | Q42507153 | ||
Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2. | Q43631715 | ||
Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse | Q43664665 | ||
Stressor categorization: acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groups. | Q43782528 | ||
Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration | Q44092251 | ||
Increased depression-like behaviors in corticotropin-releasing factor receptor-2-deficient mice: sexually dichotomous responses. | Q44495501 | ||
Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. | Q44720653 | ||
Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions. | Q44762658 | ||
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease. | Q44795484 | ||
Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse | Q46125569 | ||
Expression of c-Fos in the mouse Edinger-Westphal nucleus following ethanol administration is not secondary to hypothermia or stress | Q46794069 | ||
Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model | Q46935222 | ||
Proneness to psychological distress is associated with risk of Alzheimer's disease | Q47333653 | ||
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals. | Q48232761 | ||
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. | Q48232865 | ||
Immunohistochemical study of neurons containing corticotropin-releasing factor in Alzheimer's disease | Q48235660 | ||
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding | Q48277664 | ||
Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain | Q48279012 | ||
The role of corticotropin-releasing factor in depression and anxiety disorders | Q48328352 | ||
Stress-induced hyperphosphorylation of tau in the mouse brain | Q48397790 | ||
The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs | Q48453986 | ||
Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus | Q48467277 | ||
Elicitation and reduction of fear: behavioural and neuroendocrine indices and brain induction of the immediate-early gene c-fos | Q48700578 | ||
Dynamic changes of phosphorylated tau in mouse hippocampus after cold water stress | Q48819159 | ||
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease | Q48820847 | ||
Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety | Q49052360 | ||
Heat shock induces rapid dephosphorylation of tau in both female and male rats followed by hyperphosphorylation only in female rats: implications for Alzheimer's disease | Q49087055 | ||
Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. | Q51081847 | ||
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. | Q52200995 | ||
Mechanism of neurofibrillary degeneration in Alzheimer's disease. | Q52215509 | ||
Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. | Q52221648 | ||
Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. | Q52892360 | ||
Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. | Q52894494 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 6552-6562 | |
P577 | publication date | 2007-06-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation | |
P478 | volume | 27 |
Q37070656 | A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect |
Q36972721 | A novel mouse model for acute and long-lasting consequences of early life stress |
Q55283322 | A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress. |
Q52146763 | Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid. |
Q34067068 | Antiglucocorticoid therapy for older adults with anxiety and co-occurring cognitive dysfunction: results from a pilot study with mifepristone |
Q47145684 | Atypical, non-standard functions of the microtubule associated Tau protein |
Q38683062 | Brain Under Stress and Alzheimer's Disease |
Q30514236 | Central CRF system perturbation in an Alzheimer's disease knockin mouse model. |
Q59127908 | Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression |
Q26748974 | Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration |
Q35590867 | Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy |
Q37148516 | Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice |
Q36386509 | Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease. |
Q90883645 | Corticotropin releasing factor-binding protein (CRF-BP) as a potential new therapeutic target in Alzheimer's disease and stress disorders |
Q35801845 | Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model |
Q30754529 | Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease |
Q38657509 | Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice. |
Q35924838 | Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation |
Q51968849 | Current evidence for subjective cognitive impairment (SCI) as the pre-mild cognitive impairment (MCI) stage of subsequently manifest Alzheimer's disease. |
Q48066803 | Depression as a risk factor for Alzheimer's disease: Genes, steroids, cytokines and neurogenesis - What do we need to know? |
Q42872730 | Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease. |
Q37099485 | Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis. |
Q47114236 | Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation. |
Q33827921 | Effects of chronic stress on memory decline in cognitively normal and mildly impaired older adults |
Q34517084 | Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice |
Q34001966 | Effects of stress and stress hormones on amyloid-beta protein and plaque deposition |
Q39533185 | Exaggerated phosphorylation of brain tau protein in CRH KO mice exposed to repeated immobilization stress. |
Q27329404 | Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport |
Q90240781 | GSK-3β and ERK1/2 incongruously act in tau hyperphosphorylation in SPS-induced PTSD rats |
Q35694088 | Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease |
Q48889004 | Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress |
Q34644508 | Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor |
Q36927663 | Influence of Perceived Stress on Incident Amnestic Mild Cognitive Impairment: Results From the Einstein Aging Study |
Q35141280 | Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors |
Q36310518 | Locus Coeruleus, norepinephrine and Aβ peptides in Alzheimer's disease |
Q64231745 | Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice |
Q36788416 | Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. |
Q48339817 | Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons |
Q94552169 | Neuroprotection of Tropical Fruit Juice Mixture via the Reduction of iNOS Expression and CRH Level in β-Amyloid-Induced Rats Model of Alzheimer's Disease |
Q30405044 | Posttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses |
Q44726957 | Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration |
Q37156767 | Reconsidering Animal Models of Major Depressive Disorder in the Elderly. |
Q31110973 | Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI |
Q36222556 | Reproductive Stage and Modulation of Stress-Induced Tau Phosphorylation in Female Rats. |
Q104509552 | Reproductive status impact on tau phosphorylation induced by chronic stress |
Q90264143 | Risk Factors for Alzheimer's Disease: Focus on Stress |
Q24615033 | Sculpting the hippocampus from within: stress, spines, and CRH |
Q55129237 | Sex differences in chronic stress responses and Alzheimer's disease. |
Q36687751 | Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice |
Q53319436 | Stress acts cumulatively to precipitate Alzheimer's disease-like tau pathology and cognitive deficits. |
Q37459616 | Stress hormones mediate environment-genotype interactions during amphibian development |
Q47799198 | Stress induced neural reorganization: A conceptual framework linking depression and Alzheimer's disease. |
Q35853225 | Stress-induced anhedonia is associated with an increase in Alzheimer's disease-related markers |
Q34003380 | Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability? |
Q35894035 | Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor |
Q33820375 | Targeting psychologic stress signaling pathways in Alzheimer's disease. |
Q55300299 | Tau Phosphorylation in Female Neurodegeneration: Role of Estrogens, Progesterone, and Prolactin. |
Q30780692 | Tau protein is essential for stress-induced brain pathology |
Q48725876 | Tau protein phosphorylation in diverse brain areas of normal and CRH deficient mice: up-regulation by stress |
Q48756991 | Tau's role in the developing brain: implications for intellectual disability |
Q93203071 | Tauopathy and neurodegeneration: A role for stress |
Q55177547 | The relationship between stress and Alzheimer's disease. |
Q35762646 | The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activity |
Q37792516 | Therapeutic potential of some stress mediators in early Alzheimer's disease |
Q38195544 | Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD. |
Search more.