Mpdz is a quantitative trait gene for drug withdrawal seizures.

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Mpdz is a quantitative trait gene for drug withdrawal seizures. is …
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scholarly articleQ13442814

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P356DOI10.1038/NN1271
P698PubMed publication ID15208631
P5875ResearchGate publication ID8498778

P50authorNicole A WalterQ56995895
P2093author name stringRenee L Shirley
Kari J Buck
Matthew T Reilly
Christoph Fehr
P2860cites workGenetic studies of alcoholism and substance dependenceQ24540121
Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1Q28142235
Protein-protein interactions at G-protein-coupled receptorsQ34093414
The genetic architecture of quantitative traitsQ34100924
Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.Q43972777
Potential pleiotropic effects of Mpdz on vulnerability to seizuresQ44762332
Molecular mechanisms of glutamate receptor clustering at excitatory synapsesQ47754188
Presynaptic GABAB and adenosine A1 receptors regulate synaptic transmission to rat substantia nigra reticulata neuronesQ48576589
Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice.Q48706736
Quantitative trait loci affecting risk for pentobarbital withdrawal map near alcohol withdrawal loci on mouse chromosomes 1, 4, and 11.Q54095338
Common genetic determinants of severity of acute withdrawal from ethanol, pentobarbital and diazepam in inbred miceQ73553671
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectquantitative traitQ112670498
P304page(s)699-700
P577publication date2004-06-20
P1433published inNature NeuroscienceQ1535359
P1476titleMpdz is a quantitative trait gene for drug withdrawal seizures
P478volume7

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cites work (P2860)
Q33296351"Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice
Q365696925-HT2C and GABAB receptors influence handling-induced convulsion severity in chromosome 4 congenic and DBA/2J background strain mice
Q37550746A Systems Approach Implicates a Brain Mitochondrial Oxidative Homeostasis Co-expression Network in Genetic Vulnerability to Alcohol Withdrawal.
Q33765437A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models
Q38483636A comprehensive mouse IBD database for the efficient localization of quantitative trait loci.
Q37625601A large QTL for fear and anxiety mapped using an F2 cross can be dissected into multiple smaller QTLs.
Q30486564Ablation of Cx47 in transgenic mice leads to the loss of MUPP1, ZONAB and multiple connexins at oligodendrocyte-astrocyte gap junctions
Q46844742Acute alcohol withdrawal is associated with c-Fos expression in the basal ganglia and associated circuitry: C57BL/6J and DBA/2J inbred mouse strain analyses
Q28513488An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures
Q48158777Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer
Q27697925Biochemical and structural characterization of MUPP1-PDZ4 domain from Mus musculus
Q35754552Characterization of Genetic Differences within the Centrally Projecting Edinger-Westphal Nucleus of C57BL/6J and DBA/2J Mice by Expression Profiling
Q56602241Characterization of the quantitative trait locus for haloperidol-induced catalepsy on distal mouse chromosome 1
Q34394465Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
Q36953293Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis
Q33784674Consilience of rodent and human phenotypes relevant for alcohol dependence
Q46034717Detection of reciprocal quantitative trait loci for acute ethanol withdrawal and ethanol consumption in heterogeneous stock mice.
Q37386396Discovering genes involved in alcohol dependence and other alcohol responses: role of animal models
Q40416954Dissection of Host Susceptibility to Bacterial Infections and Its Toxins
Q58700696Distinct Roles for Two Chromosome 1 Loci in Ethanol Withdrawal, Consumption, and Conditioned Place Preference
Q35845414Dual-trait selection for ethanol consumption and withdrawal: genetic and transcriptional network effects
Q33980507Establishment of epithelial polarity--GEF who's minding the GAP?
Q44908892Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice.
Q33764340FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice
Q35090881Finding the molecular basis of complex genetic variation in humans and mice
Q34019187Fine-mapping QTLs in advanced intercross lines and other outbred populations
Q40396620Gene expression differences in mice divergently selected for methamphetamine sensitivity
Q40135048Genetic analysis reveals polygenic influences on iron, copper, and zinc in mouse hippocampus with neurobiological implications
Q37953793Genetic contributions to behavioural diversity at the gene-environment interface
Q37117548Genetic factors influencing alcohol dependence
Q37460560Genetic research: who is at risk for alcoholism
Q39101511Genetic studies of alcohol dependence in the context of the addiction cycle
Q37784879Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development
Q33681743Genetics and genomics of alcohol sensitivity
Q33940849Genomic analysis of individual differences in ethanol drinking: evidence for non-genetic factors in C57BL/6 mice.
Q29031408Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking
Q28551468Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity
Q34016635Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics
Q35683906Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains
Q37784880Identifying Quantitative Trait Loci (QTLs) and Genes (QTGs) for Alcohol-Related Phenotypes in Mice
Q24810638Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli
Q36786335Interval-specific congenic animals for high-resolution quantitative trait loci mapping
Q35747234Involvement of the limbic basal ganglia in ethanol withdrawal convulsivity in mice is influenced by a chromosome 4 locus
Q36298365Laboratory models of alcoholism: treatment target identification and insight into mechanisms
Q30492936Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol.
Q36020037Modeling the diagnostic criteria for alcohol dependence with genetic animal models
Q34559903Mpdz expression in the caudolateral substantia nigra pars reticulata is crucially involved in alcohol withdrawal
Q37719842Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption.
Q42229168Persistent enhancement of ethanol drinking following a monosodium glutamate-substitution procedure in C57BL6/J and DBA/2J mice
Q37349672Protein-protein interactions as therapeutic targets in neuropsychopharmacology
Q33816498QTL mapping in outbred populations: successes and challenges
Q35977357Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross.
Q37386611Quantitative trait locus analysis: multiple cross and heterogeneous stock mapping
Q30480163Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping
Q89850947RNA-Seq Analysis of Genetic and Transcriptome Network Effects of Dual-Trait Selection for Ethanol Preference and Withdrawal Using SOT and NOT Genetic Models
Q35011307Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling
Q37024172Review. Neurogenetic studies of alcohol addiction
Q34071914Role of the axonal initial segment in psychiatric disorders: function, dysfunction, and intervention
Q41884067Rostroventral caudate putamen involvement in ethanol withdrawal is influenced by a chromosome 4 locus
Q33642386Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry
Q36085684Strategies for mapping and cloning quantitative trait genes in rodents
Q35747217Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models
Q30469513Substantia nigra pars reticulata is crucially involved in barbiturate and ethanol withdrawal in mice
Q46672501The PDZ protein mupp1 promotes Gi coupling and signaling of the Mt1 melatonin receptor
Q35907566The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks
Q38174431The genetics of gene expression in complex mouse crosses as a tool to study the molecular underpinnings of behavior traits
Q36003609The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia
Q39398827The relevance of inter- and intrastrain differences in mice and rats and their implications for models of seizures and epilepsy.
Q46493868The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2.
Q26860461Translational behaviour-genetic studies of alcohol: are we there yet?
Q37968513Translational genetic approaches to substance use disorders: bridging the gap between mice and humans
Q28728240Using expression genetics to study the neurobiology of ethanol and alcoholism
Q28655514Using genome-wide expression profiling to define gene networks relevant to the study of complex traits: from RNA integrity to network topology
Q36197596mGluR7 genetics and alcohol: intersection yields clues for addiction

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