Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.

scientific article

Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/MC.20018
P698PubMed publication ID15224346

P2093author name stringShun-Fa Yang
Shu-Chen Chu
Yih-Shou Hsieh
Hui-Ling Chiou
Pei-Ni Chen
P2860cites workMatrix metalloproteinases and cellular fibrinolytic activityQ28200820
Comparative electrophoretic analysis of human and porcine plasminogen activators in sds-polyacrylamide gels containing plasminogen and caseinQ50928812
P433issue3
P921main subjectlung cancerQ47912
P304page(s)143-149
P577publication date2004-07-01
P1433published inMolecular CarcinogenesisQ15724597
P1476titleSilibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
P478volume40

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cites work (P2860)
Q34649335"Silymarin", a promising pharmacological agent for treatment of diseases
Q39611544Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway
Q38819264Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo
Q28480863Antimetastatic effects of norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-kB activity
Q37591742Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer
Q47244446Antimetastatic potentials of Phyllanthus urinaria L on A549 and Lewis lung carcinoma cells via repression of matrix-degrading proteases
Q37222477Antitumor and antioxidant status of Terminalia catappa against Ehrlich ascites carcinoma in Swiss albino mice
Q93377959Chemopreventive Effects of Silibinin on Colitis-Associated Tumorigenesis by Inhibiting IL-6/STAT3 Signaling Pathway
Q26998615Chemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancer
Q41482491Cochinchina momordica seed suppresses proliferation and metastasis in human lung cancer cells by regulating multiple molecular targets
Q92945264Combination of Epigallocatechin-3-gallate and Silibinin: A Novel Approach for Targeting Both Tumor and Endothelial Cells
Q35231826Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells
Q38018255Diet, nutrients, phytochemicals, and cancer metastasis suppressor genes
Q64238344Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers
Q51074577Duchesnea indica extract suppresses the migration of human lung adenocarcinoma cells by inhibiting epithelial-mesenchymal transition.
Q51743221Effect of Silibinin on Maspin and ERα Gene Expression in MCF-7 Human Breast Cancer Cell Line.
Q36021045Effect of Terminalia catappa on lipid profile in transplanted fibrosarcoma in rats
Q34583094Effects and mechanisms of silibinin on human hepatoma cell lines
Q38826628Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway
Q55001114Evaluation of Silibinin Effects on the Viability of HepG2 (Human hepatocellular liver carcinoma) and HUVEC (Human Umbilical Vein Endothelial) Cell Lines.
Q37982235Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities
Q34505655Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
Q38287362Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production
Q37040604Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
Q47100235Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells.
Q38751101In Vitro Co-Delivery Evaluation of Novel Pegylated Nano-Liposomal Herbal Drugs of Silibinin and Glycyrrhizic Acid (Nano-Phytosome) to Hepatocellular Carcinoma Cells.
Q35375383Increase in apoptosis by combination of metformin with silibinin in human colorectal cancer cells
Q47133287Increased Loading, Efficacy and Sustained Release of Silibinin, a Poorly Soluble Drug Using Hydrophobically-Modified Chitosan Nanoparticles for Enhanced Delivery of Anticancer Drug Delivery Systems.
Q39161189Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells.
Q37381478Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction
Q26995304Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer
Q24655042Multitargeted therapy of cancer by silymarin
Q28079909Protective effect of silymarin against chemical-induced cardiotoxicity
Q34449752Protocatechuic acid inhibits cancer cell metastasis involving the down‐regulation of Ras/Akt/NF‐κB pathway and MMP‐2 production by targeting RhoB activation
Q42366615Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer.
Q24631327Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Q34992866Selaginella tamariscina extract suppresses TPA-induced invasion and metastasis through inhibition of MMP-9 in human nasopharyngeal carcinoma HONE-1 cells
Q50720323Silibinin Improves TNF-α and M30 Expression and Histological Parameters in Rat Kidneys After Hepatic Ischemia/Reperfusion.
Q38719605Silibinin induces hepatic stellate cell cycle arrest via enhancing p53/p27 and inhibiting Akt downstream signaling protein expression.
Q36984408Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells
Q34627739Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators
Q40312065Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway
Q33552842Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression
Q39541974Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel
Q34659546Silibinin suppresses CD44 expression in prostate cancer cells
Q39772964Silibinin suppresses TNF-alpha-induced MMP-9 expression in gastric cancer cells through inhibition of the MAPK pathway
Q42541201Silybin from Silybum Marianum Seeds Inhibits Confluent-Induced Keratinocytes Differentiation as Effectively as Retinoic Acid without Inducing Inflammatory Cytokine
Q64933009Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells.
Q36690472Silymarin and epithelial cancer chemoprevention: how close we are to bedside?
Q39455124Silymarin inhibits cervical cancer cell through an increase of phosphatase and tensin homolog
Q50488471Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 breast adenocarcinoma cells invasion/migration by α-tomatine through activating PKCα/ERK/NF-κB-dependent MMP-2/MMP-9 expressions.
Q39463690Synergistic effects of arsenic trioxide and silibinin on apoptosis and invasion in human glioblastoma U87MG cell line.
Q37667106Targeting silibinin in the antiproliferative pathway
Q37585138Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy
Q34411650The role of sodium-dependent glucose transporter 1 and glucose transporter 2 in the absorption of cyanidin-3-o-β-glucoside in Caco-2 cells
Q64946955Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
Q38954969Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway
Q39498880Y27632 attenuates the aristolochic acid-promoted invasion and migration of human urothelial cancer TSGH cells in vitro and inhibits the growth of xenografts in vivo
Q39603276α-Tomatine suppresses invasion and migration of human non-small cell lung cancer NCI-H460 cells through inactivating FAK/PI3K/Akt signaling pathway and reducing binding activity of NF-κB.

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