A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

scientific article

A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMTHE.2004.04.008
P698PubMed publication ID15272480

P50authorMichela A. DentiQ38320761
Alessandro RosaQ41002249
P2093author name stringFernanda Gabriella De Angelis
Irene Bozzoni
Olga Sthandier
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Nuclear export of microRNA precursorsQ27860686
Asymmetry in the assembly of the RNAi enzyme complexQ27860763
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
Functional siRNAs and miRNAs Exhibit Strand BiasQ27861038
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cellsQ28207586
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cellsQ28215061
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
A DNA vector-based RNAi technology to suppress gene expression in mammalian cellsQ29616551
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cellsQ30476196
Chimeric snRNA molecules carrying antisense sequences against the splice junctions of exon 51 of the dystrophin pre-mRNA induce exon skipping and restoration of a dystrophin synthesis in Delta 48-50 DMD cellsQ34035676
siRNA-mediated gene silencing in vitro and in vivo.Q34150604
Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.Q34156507
Small nuclear RNA genes: a model system to study fundamental mechanisms of transcriptionQ34272362
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation.Q34302582
Functional siRNA expression from transfected PCR productsQ34364847
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cellsQ34460403
Gene silencing in mammals by small interfering RNAsQ34931992
Yeast RNase III as a key processing enzyme in small nucleolar RNAs metabolism.Q38330838
Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cellsQ38340941
Promoter choice affects the potency of HIV-1 specific RNA interferenceQ39959002
The proximal promoter and the start site cooperate to specify correct U1 snRNA transcription initiation by RNA polymerase II.Q40421543
Effective expression of small interfering RNA in human cellsQ40735246
Inhibition of human immunodeficiency virus type 1 replication by nuclear chimeric anti-HIV ribozymes in a human T lymphoblastoid cell lineQ41049538
3' end formation of U1 snRNA precursors is coupled to transcription from snRNA promotersQ43562909
Expression of small, therapeutic RNAs in human cell nuclei.Q45881025
Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elementsQ69638046
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)191-199
P577publication date2004-07-01
P1433published inMolecular TherapyQ15762400
P1476titleA new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells
P478volume10

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