Characterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR.

scientific article published on 9 August 2012

Characterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2012.07.076
P698PubMed publication ID22986343
P5875ResearchGate publication ID230870311

P2093author name stringYong Sun Lee
Kwang Soo Lee
Betty H Johnson
Bin Gong
Kwanbok Lee
Nawapol Kunkeaw
Sung Ho Jeon
Chanvit Leelayuwat
Luis Marcelo F Holthauzen
P2860cites workPrecursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity.Q24633674
The dsRNA protein kinase PKR: virus and cell controlQ28298945
Evolution and functions of long noncoding RNAsQ29614331
Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.Q30468875
Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixesQ30472022
Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR.Q31778073
In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosinQ33633828
Regulation of innate immunity through RNA structure and the protein kinase PKR.Q34786169
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AMLQ35651714
Activation of PKR: an open and shut case?Q36695833
Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization propertiesQ38352344
A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.Q40430436
Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activityQ41507672
Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanismQ42158761
Functional characterization of the RNA-binding domain and motif of the double-stranded RNA-dependent protein kinase DAI (PKR).Q42686037
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectnon-coding RNAQ427087
P304page(s)3477-3484
P577publication date2012-08-09
P1433published inFEBS LettersQ1388051
P1476titleCharacterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR.
P478volume586

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cites work (P2860)
Q26801690A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression
Q89850950A guide to naming human non-coding RNA genes
Q58732375A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1
Q34883331A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1
Q36396528A tumor surveillance model: a non-coding RNA senses neoplastic cells and its protein partner signals cell death
Q37407462Cell death/proliferation roles for nc886, a non-coding RNA, in the protein kinase R pathway in cholangiocarcinoma
Q34044808Dissection of the adenoviral VA RNAI central domain structure reveals minimum requirements for RNA-mediated inhibition of PKR.
Q33976897Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis
Q40378767Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR.
Q36401117Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients
Q46946250Increased microRNA-323-3p in IL-22/IL-17-producing T cells and asthma: a role in the regulation of the TGF-β pathway and IL-22 production
Q35048886Links between the oncoprotein YB-1 and small non-coding RNAs in breast cancer
Q64078118Mechanism mediated by a noncoding RNA, nc886, in the cytotoxicity of a DNA-reactive compound
Q26770685Molecular mechanisms of long noncoding RNAs on gastric cancer
Q60309440Mother-child transmission of epigenetic information by tunable polymorphic imprinting
Q48261248Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth.
Q36337663Robust expression of vault RNAs induced by influenza A virus plays a critical role in suppression of PKR-mediated innate immunity
Q38712127Silencing nc886, a Non-Coding RNA, Induces Apoptosis of Human Endometrial Cancer Cells-1A In Vitro
Q64076950The search for a PKR code-differential regulation of protein kinase R activity by diverse RNA and protein regulators
Q92795173The vault RNA of Trypanosoma brucei plays a role in the production of trans-spliced mRNA
Q35225674Toll-like receptor-3 is dispensable for the innate microRNA response to West Nile virus (WNV).
Q89657713Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy
Q33779206Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.
Q33977148nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer
Q89861842vtRNA2-1/nc886 Produces a Small RNA That Contributes to Its Tumor Suppression Action through the microRNA Pathway in Prostate Cancer

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