A disaccharide derived from chondroitin sulphate proteoglycan promotes central nervous system repair in rats and mice

scientific article published in October 2004

A disaccharide derived from chondroitin sulphate proteoglycan promotes central nervous system repair in rats and mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1460-9568.2004.03676.X
P698PubMed publication ID15450076
P5875ResearchGate publication ID8265394

P50authorMichal SchwartzQ21264411
Asya RollsQ37834540
Sima LevQ89166477
Liora CahalonQ125288776
Hila AvidanQ125289639
P2093author name stringOfer Lider
Vladimir Litvak
Hadas Schori
Sharon Bakalash
P2860cites workBrevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sitesQ28138661
Regeneration beyond the glial scarQ28239915
Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoformsQ28566182
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissueQ28566378
M6a acts as a nerve growth factor-gated Ca(2+) channel in neuronal differentiationQ28581571
Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrinsQ28582208
Rho GTPases in growth cone guidanceQ28647606
Chondroitinase ABC promotes functional recovery after spinal cord injuryQ29615017
Analysis of nitrate, nitrite, and [15N]nitrate in biological fluidsQ29616817
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonQ29620156
FAK and PYK2/CAKbeta in the nervous system: a link between neuronal activity, plasticity and survival?Q33650545
Nervous system proteoglycans as modulators of neurite outgrowthQ33855404
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomyQ34486849
Glutamate neurotoxicity and diseases of the nervous systemQ34560997
Vaccination for protection of retinal ganglion cells against death from glutamate cytotoxicity and ocular hypertension: implications for glaucomaQ34734517
Signaling mechanisms that regulate actin-based motility processes in the nervous system.Q34975998
Reciprocal interactions between microglia and neurons: from survival to neuropathologyQ34982917
Nogo on the go.Q34984937
The extracellular matrix in axon regenerationQ35002818
Increasing plasticity and functional recovery of the lesioned spinal cordQ35002827
Macrophages and microglia in central nervous system injury: are they helpful or harmful?Q35101280
The essentiality of Bcl-2, PKC and proteasome–ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagilineQ35557679
Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting propertiesQ36234537
Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retractionQ36880910
Neurite outgrowth inhibition by chondroitin sulfate proteoglycan: stalling/stopping exceeds turning in human neuroblastoma growth conesQ39119113
Protein kinase C mediates neurite guidance at an astrocyte boundary.Q40821189
Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan.Q42523079
T-cell-based immunity counteracts the potential toxicity of glutamate in the central nervous systemQ43755775
Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incisionQ44044356
Determination of the chondroitin sulfate disaccharides in dog and horse plasma by HPLC using chondroitinase digestion, precolumn derivatization, and fluorescence detectionQ44068169
Neuroprotection by T-cells depends on their subtype and activation state.Q44225637
PKC isozymes in the enhanced regrowth of retinal neurites after optic nerve injuryQ44453168
Synergistic expression of inducible nitric oxide synthase by phorbol ester and interferon-gamma is mediated through NF-kappaB and ERK in microglial cellsQ44556486
Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substratesQ47978419
Oversulfated dermatan sulfate exhibits neurite outgrowth-promoting activity toward embryonic mouse hippocampal neurons: implications of dermatan sulfate in neuritogenesis in the brainQ48226726
Activation of ERK1/2 after neonatal rat cerebral hypoxia-ischaemiaQ48249958
Hypoxia induces nitric oxide production in mouse microglia via p38 mitogen-activated protein kinase pathwayQ48454985
Developmental regulation of the sulfation profile of chondroitin sulfate chains in the chicken embryo brainQ48541947
Immunohistochemical localization of neurocan and L1 in the formation of thalamocortical pathway of developing ratsQ48685302
Phosphorylation of extracellular signal-regulated kinases 1/2 is predominantly enhanced in the microglia of the rat spinal cord following dorsal root transection.Q51295133
Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.Q52538801
Kinetics of facial motoneuron loss following facial nerve transection in severe combined immunodeficient mice.Q52541193
Emerging roles for semaphorins in neural regenerationQ56592755
Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral SphingomyelinaseQ57372021
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectdisaccharideQ173600
P304page(s)1973-1983
P577publication date2004-10-01
P1433published inEuropean Journal of NeuroscienceQ5412733
P1476titleA disaccharide derived from chondroitin sulphate proteoglycan promotes central nervous system repair in rats and mice
P478volume20

Reverse relations

cites work (P2860)
Q46905205A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death
Q37822693Chemical priming for spinal cord injury: a review of the literature part II-potential therapeutics
Q37822292Chemical priming for spinal cord injury: a review of the literature. Part I-factors involved
Q35649647Chondroitin Sulfate Induces Depression of Synaptic Transmission and Modulation of Neuronal Plasticity in Rat Hippocampal Slices
Q45864337Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype.
Q36713876Chondroitin sulfate proteoglycan and its degradation products in CNS repair
Q36713861Chondroitin sulfate proteoglycans in tumor progression
Q45392051Chondroitin sulfate, a major component of the perineuronal net, elicits inward currents, cell depolarization, and calcium transients by acting on AMPA and kainate receptors of hippocampal neurons
Q36713871Chondroitin/Dermatan sulfates in the central nervous system: their structures and functions in health and disease
Q38120433Combination treatment with chondroitinase ABC in spinal cord injury--breaking the barrier
Q42627909Down-regulation of microglia and NG2-positive cells reaction in trimethyltin-injured hippocampus of rats treated with myelin basic protein-reactive T cells: possible contribution to the neuroprotective effect of T cells.
Q38602852Effect of chondroitinase ABC on inflammatory and oxidative response following spinal cord injury
Q39510798Effects of chondroitin sulfate and its oligosaccharides on toll-like receptor-mediated IL-6 secretion by macrophage-like J774.1 cells
Q37928624Extracellular matrix and perineuronal nets in CNS repair
Q38206485Glial scar and immune cell involvement in tissue remodeling and repair following acute CNS injuries
Q33327037Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.
Q34069452Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis
Q37310621Immunomodulatory and anti-inflammatory effects of chondroitin sulphate
Q37109132Knocking down glycosaminoglycan synthesis.
Q35670813Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway
Q37983759Microglial carbohydrate-binding receptors for neural repair.
Q90629410Plasticity Induced Recovery of Breathing Occurs at Chronic Stages after Cervical Contusion
Q49155880Reduction of brain injury in neonatal hypoxic-ischemic rats by intracerebroventricular injection of neural stem/progenitor cells together with chondroitinase ABC.
Q33734430Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury
Q34798895Targeted downregulation of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase significantly mitigates chondroitin sulfate proteoglycan-mediated inhibition
Q37396812The bright side of the glial scar in CNS repair
Q35923626The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury
Q28757375Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation

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