| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.YMGME.2004.07.007 |
| P698 | PubMed publication ID | 15464433 |
| P2093 | author name string | Kelli S Bramlett | |
| Thomas P Burris | |||
| Keith A Houck | |||
| Christopher D Hepler | |||
| Jeffrey S Thomas | |||
| Kristen M Borchert | |||
| Laura F Michael | |||
| P2860 | cites work | Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors | Q24290397 |
| Role of LXRs in control of lipogenesis | Q24290548 | ||
| Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway | Q24316367 | ||
| LXR, a nuclear receptor that defines a distinct retinoid response pathway | Q24317347 | ||
| Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta | Q24598068 | ||
| Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids | Q28141468 | ||
| Orphan nuclear receptor modulators | Q28235059 | ||
| An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha | Q28294042 | ||
| Identification of a nuclear receptor that is activated by farnesol metabolites | Q28302684 | ||
| A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis | Q29617241 | ||
| A natural product ligand of the oxysterol receptor, liver X receptor. | Q30974044 | ||
| Identification of a chemical tool for the orphan nuclear receptor FXR. | Q31431724 | ||
| Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines | Q32100864 | ||
| Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. | Q35763029 | ||
| Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. | Q38300264 | ||
| A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor. | Q44222492 | ||
| Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers | Q74253388 | ||
| P433 | issue | 1-2 | |
| P304 | page(s) | 184-187 | |
| P577 | publication date | 2004-09-01 | |
| P1433 | published in | Molecular Genetics and Metabolism | Q6895949 |
| P1476 | title | T0901317 is a dual LXR/FXR agonist | |
| P478 | volume | 83 |
| Q38435111 | A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand Interactions |
| Q39338520 | A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products. |
| Q35134909 | A liver-X-receptor ligand, T0901317, attenuates IgE production and airway remodeling in chronic asthma model of mice |
| Q34287702 | Action of RORs and their ligands in (patho)physiology. |
| Q37615062 | Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells |
| Q36352141 | Activation of liver X receptor inhibits osteopontin and ameliorates diabetic nephropathy |
| Q37507576 | Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection |
| Q33934005 | Anti-proliferative effect of LXR agonist T0901317 in ovarian carcinoma cells |
| Q34128708 | Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. |
| Q98464918 | Assessing the Selectivity of FXR, LXRs, CAR, and RORγ Pharmaceutical Ligands With Reporter Cell Lines |
| Q57787121 | Atorvastatin upregulates apolipoprotein M expression via attenuating LXRα expression in hyperlipidemic apoE-deficient mice |
| Q38702009 | B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals. |
| Q42583421 | Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization |
| Q43076638 | Cholesterol homeostasis in the retina: seeing is believing |
| Q27303244 | Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders |
| Q36870419 | E17110 promotes reverse cholesterol transport with liver X receptor β agonist activity in vitro |
| Q47807772 | Editor's Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis |
| Q34550999 | Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR |
| Q36727402 | Evolution of the bile salt nuclear receptor FXR in vertebrates |
| Q61813678 | Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro |
| Q28266284 | Farnesoid X receptor: from medicinal chemistry to clinical applications |
| Q33636261 | Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice |
| Q49898436 | Fat-specific protein 27 is a novel target gene of liver X receptor α. |
| Q34146912 | Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages. |
| Q34097208 | High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions. |
| Q61818543 | Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease |
| Q64252650 | Identification of FDA-approved drugs targeting the Farnesoid X Receptor |
| Q33636952 | Identification of MIG12 as a mediator for stimulation of lipogenesis by LXR activation |
| Q34414231 | Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. |
| Q34789625 | Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist |
| Q35066157 | Identification of a selective agonist for liver X receptor α (LXRα) via screening of a synthetic compound library |
| Q34174694 | Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis? |
| Q34287799 | Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity |
| Q38102608 | LXR agonists: new potential therapeutic drug for neurodegenerative diseases |
| Q34360087 | LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression |
| Q45982093 | LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. |
| Q91916968 | LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target |
| Q42464128 | LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux |
| Q34115001 | Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics |
| Q30426995 | Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice |
| Q34519854 | Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation |
| Q49036874 | Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells |
| Q34462811 | Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation. |
| Q99608561 | Liver X receptor β is required for the survival of single-positive thymocytes by regulating IL-7Rα expression |
| Q35096502 | Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2 |
| Q61249098 | Liver X receptors and copper metabolism: New frontiers for the oxysterol receptors |
| Q36460531 | Liver X receptors and fat cell metabolism |
| Q47155172 | Liver X receptors as potential targets for cancer therapeutics |
| Q37976890 | Liver X receptors bridge hepatic lipid metabolism and inflammation |
| Q30371540 | Macrophage-independent regulation of reverse cholesterol transport by liver X receptors. |
| Q38857349 | Metabolic regulation of magnolol on the nuclear receptor, liver X receptor |
| Q38062510 | Natural compounds regulate energy metabolism by the modulating the activity of lipid-sensing nuclear receptors. |
| Q26825692 | Nuclear receptors and their selective pharmacologic modulators |
| Q48112560 | Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect |
| Q33967334 | Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor |
| Q93190731 | PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells |
| Q57284658 | Prevention of Cell Growth by Suppression of Villin Expression in Lithocholic Acid-stimulated HepG2 Cells |
| Q38737295 | Progress in the medicinal chemistry of silicon: C/Si exchange and beyond |
| Q39495324 | Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist |
| Q34407313 | REV-ERB and ROR nuclear receptors as drug targets. |
| Q37376541 | RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer |
| Q48986828 | Regulation of Oligodendrocyte Differentiation and Myelination by Nuclear Receptors: Role in Neurodegenerative Disorders |
| Q42049578 | Regulation of human apolipoprotein m gene expression by orphan and ligand-dependent nuclear receptors. |
| Q33803303 | Regulation of type 1 iodothyronine deiodinase by LXRα |
| Q35464846 | T0901317 inhibits cisplatin-induced apoptosis in ovarian cancer cells [corrected] |
| Q35560513 | TO901317 regulating apolipoprotein M expression mediates via the farnesoid X receptor pathway in Caco-2 cells |
| Q38382991 | Targeting liver X receptors in cancer therapeutics |
| Q37825904 | Targeting liver X receptors in human health: deadlock or promising trail? |
| Q64269294 | The Liver X Receptor Agonist TO901317 Ameliorates Behavioral Deficits in Two Mouse Models of Autism |
| Q35099319 | The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis |
| Q33613397 | The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist. |
| Q38703765 | The emerging roles of liver X receptors and their ligands in cancer. |
| Q33811323 | The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. |
| Q90119144 | The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy |
| Q37219788 | The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells |
| Q46617017 | Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice |
Search more.