Quantitative deuterium isotopic profiling at natural abundance indicates mechanistic differences for delta 12-epoxidase and delta 12-desaturase in Vernonia galamensis

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Quantitative deuterium isotopic profiling at natural abundance indicates mechanistic differences for delta 12-epoxidase and delta 12-desaturase in Vernonia galamensis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M500909200
P698PubMed publication ID15722338
P5875ResearchGate publication ID8011789

P50authorRichard J. RobinsQ43238910
P2093author name stringIsabelle Billault
Jia-Rong Duan
Sébastien Guiet
P2860cites workDESATURATION AND RELATED MODIFICATIONS OF FATTY ACIDS1Q28249518
Identification of non-heme diiron proteins that catalyze triple bond and epoxy group formationQ28269789
Structure and expression of fatty acid desaturasesQ28285013
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Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidantQ34461803
Non-heme iron oxygenasesQ34662093
The bioinorganic chemistry of iron in oxygenases and supramolecular assembliesQ34913874
Multiple oxidants and multiple mechanisms in cytochrome P450 catalysisQ35589722
Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificityQ38291662
Evidence for cytochrome b5 as an electron donor in ricinoleic acid biosynthesis in microsomal preparations from developing castor bean (Ricinus communis L.)Q42204280
Reaction of 5-ethynyl-2'-deoxyuridylate with thiols and thymidylate synthetaseQ42248381
Natural deuterium distribution in fatty acids isolated from peanut seed oil: a site-specific study by quantitative 2H NMR spectroscopyQ44120150
Quantitative 2H NMR analysis of deuterium distribution in petroselinic acid isolated from parsley seedQ44567255
Deuterium NMR used to indicate a common mechanism for the biosynthesis of ricinoleic acid by Ricinus communis and Claviceps purpureaQ44793872
Regioselectivity of a plant lauric acid omega hydroxylase. Omega hydroxylation of cis and trans unsaturated lauric acid analogs and epoxygenation of the terminal olefin by plant cytochrome P-450Q47857097
Systematics of 2H patterns in natural compounds and its importance for the elucidation of biosynthetic pathwaysQ56698080
Biosynthesis of vernoleate (cis-12-epoxyoctadeca-cis-9-enoate) in microsomal preparations from developing endosperm of Euphorbia lagascaeQ70706223
Regio- and stereoselectivity of cytochrome P-450 and peroxygenase-dependent formation of cis-12,13-epoxy-9(Z)-octadecenoic acid (vernolic acid) in Euphorbia lagascaeQ72673455
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectVernonia galamensisQ3556010
P1104number of pages7
P304page(s)17645-17651
P577publication date2005-02-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleQuantitative deuterium isotopic profiling at natural abundance indicates mechanistic differences for delta 12-epoxidase and delta 12-desaturase in Vernonia galamensis
P478volume280

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cites work (P2860)
Q51475721Analysis of NAD 2D-NMR spectra of saturated fatty acids in polypeptide aligning media by experimental and modeling approaches.
Q33408689Investigation of fatty acid elongation and desaturation steps in Fusarium lateritium by quantitative two-dimensional deuterium NMR spectroscopy in chiral oriented media
Q55113348Probing substrate–product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes
Q33362416Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle

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