No relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis

scientific article

No relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.20568
P698PubMed publication ID15726657
P5875ResearchGate publication ID8006315

P2093author name stringUlrich Beuers
Karin Dilger
Malte H J Heeg
Annette Denk
P2860cites workNuclear receptor response elements mediate induction of intestinal MDR1 by rifampinQ28211706
A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study GroupQ28243457
Effects of long-term rifampicin administration in primary biliary cirrhosisQ28319860
The human bile salt export pump: characterization of substrate specificity and identification of inhibitorsQ28612066
Genetic variability in CYP3A5 and its possible consequences.Q30341330
Cytochrome P-450 3A4: regulation and role in drug metabolismQ33636632
Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseasesQ33723536
Randomised controlled trials of ursodeoxycholic-acid therapy for primary biliary cirrhosis: a meta-analysisQ33745849
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisitedQ34146325
Sex is a major determinant of CYP3A4 expression in human liverQ34265530
Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'.Q34330984
Regulation of cyp3a gene transcription by the pregnane x receptorQ34504007
The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?Q34615575
In vitro and in vivo drug interactions involving human CYP3A.Q34663451
Extrahepatic manifestations of cholestasisQ34776437
Review article: pruritus in cholestatic and other liver diseasesQ35091959
Pharmacokinetic interactions with rifampicin : clinical relevanceQ35185727
Urinary 6?-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animalsQ35579020
The effect of ursodeoxycholic acid therapy on liver fibrosis progression in primary biliary cirrhosisQ40737262
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.Q40784945
Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.Q40785589
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampinQ40851439
Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosisQ40883127
Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoproteinQ42468905
Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activitiesQ44080027
Pharmacokinetics and pharmacodynamic action of budesonide in early- and late-stage primary biliary cirrhosisQ44493764
The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activityQ44579595
Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimensQ44787212
The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.Q51521480
Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis.Q52552319
Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use.Q52920374
Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymesQ57012049
Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activityQ61794839
Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: a placebo-controlled trialQ68019501
Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trialQ69357047
Differential induction of prehepatic and hepatic metabolism of verapamil by rifampinQ71650801
Ursodeoxycholic acid in the treatment of primary biliary cirrhosisQ72401649
Time course of the changes in prednisolone pharmacokinetics after co-administration or discontinuation of rifampinQ72693322
Oral budesonide and ursodeoxycholic acid for treatment of primary biliary cirrhosis: results of a prospective double-blind trialQ73026352
Ursodeoxycholic acid for primary biliary cirrhosisQ73497916
Long-term effects of ursodeoxycholic acid in primary biliary cirrhosis: results of a double-blind controlled multicentric trial. UDCA-Cooperative Group from the Spanish Association for the Study of the LiverQ73715566
Ten-year survival in ursodeoxycholic acid-treated patients with primary biliary cirrhosis. The UDCA-PBC Study GroupQ77807948
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectprimary biliary cholangitisQ1072420
P304page(s)595-602
P577publication date2005-03-01
P1433published inHepatologyQ15724398
P1476titleNo relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis
P478volume41

Reverse relations

cites work (P2860)
Q33866454Concept on the pathogenesis and treatment of primary biliary cirrhosis
Q36495172Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis
Q64939082Drug-Drug Interactions of Infectious Disease Treatments in Low-Income Countries: A Neglected Topic?
Q40183754Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
Q46716764Influence of CYP3A4, CYP3A5, and ABCB1 genotype and expression on budesonide pharmacokinetics: a possible role of intestinal CYP3A4 expression
Q38774857Management of cholestatic disease in 2017.
Q34017604Medical treatment of cholestatic liver diseases: From pathobiology to pharmacological targets
Q37254347Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators?
Q35741546New perspectives for the treatment of cholestasis: lessons from basic science applied clinically
Q46940563Nuclear receptors, bile-acid detoxification, and cholestasis
Q84230884Primary biliary cirrhosis
Q37841609The impact of cholesterol and its metabolites on drug metabolism
Q37919924Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.

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