scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0306-9877(96)90071-7 |
P698 | PubMed publication ID | 8910880 |
P2093 | author name string | Ying W | |
P2860 | cites work | Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis | Q24306886 |
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis | Q28335672 | ||
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation | Q29547561 | ||
Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia | Q33322579 | ||
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis | Q34300016 | ||
Excitatory amino acids as a final common pathway for neurologic disorders. | Q34321926 | ||
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid | Q34384772 | ||
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? | Q35254212 | ||
The oxidant stress hypothesis in Parkinson's disease: evidence supporting it | Q35626743 | ||
Calcium as sculptor and destroyer of neural circuitry | Q35680713 | ||
IgG from amyotrophic lateral sclerosis patients increases current through P-type calcium channels in mammalian cerebellar Purkinje cells and in isolated channel protein in lipid bilayer | Q36724305 | ||
Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease | Q36760254 | ||
Oxygen radicals and neuropsychiatric illness. Some speculations | Q37152812 | ||
What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies | Q37578887 | ||
Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? | Q37936915 | ||
Bioenergetic and oxidative stress in neurodegenerative diseases | Q40369216 | ||
Age-related changes in cerebral oxidative metabolism. Implications for drug therapy. | Q40450162 | ||
Aging, energy, and oxidative stress in neurodegenerative diseases. | Q40478731 | ||
Amyotrophic lateral sclerosis is a multifactorial disease | Q40546531 | ||
Ion transport systems and Ca2+ regulation in aging neurons. | Q40586893 | ||
Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice | Q40612435 | ||
Magnesium and Calcium Contents in CNS Tissues of Amyotrophic Lateral Sclerosis Patients from the Kii Peninsula, Japan | Q41083434 | ||
Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists | Q41154685 | ||
The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis | Q41413618 | ||
Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin | Q41458956 | ||
Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam | Q41624368 | ||
Marked increase in mitochondrial DNA deletion levels in the cerebral cortex of Huntington's disease patients | Q41652065 | ||
Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells | Q41843416 | ||
Striatal deficiency of L-pyroglutamic acid in Huntington's disease is accompanied by increased plasma levels | Q42204389 | ||
Striatal calcium channel antagonist receptors in Huntington's disease and Parkinson's disease | Q42506358 | ||
Deleterious network hypothesis of Alzheimer's disease | Q44245798 | ||
Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study | Q44254770 | ||
Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease | Q44480462 | ||
Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence | Q44498466 | ||
Muscle lactate dehydrogenase activity is decreased in murine motor neuron disease | Q44580826 | ||
Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats | Q44848373 | ||
Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. | Q44934024 | ||
Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization | Q45291026 | ||
Excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson's and Huntington's diseases | Q45293874 | ||
The mechanism of glutamate-induced degeneration of cultured Huntington's disease and control fibroblasts | Q45296572 | ||
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity | Q46070812 | ||
Point mutations of mitochondrial genome in Parkinson's disease | Q48075275 | ||
An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease | Q48184003 | ||
NMDA-dependent superoxide production and neurotoxicity | Q48234286 | ||
Parkinson's disease and basal ganglia calcifications: prevalence and clinico-radiological correlations | Q52046704 | ||
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria | Q54965159 | ||
Brainstem motoneuron pools that are selectively resistant in amyotrophic lateral sclerosis are preferentially enriched in parvalbumin: Evidence from monkey brainstem for a calcium-mediated mechanism in sporadic ALS | Q57540072 | ||
Oxidative damage to protein in sporadic motor neuron disease spinal cord | Q59544371 | ||
Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease | Q59544375 | ||
Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease | Q71694543 | ||
A role for amplified protein kinase C activity in the pathogenesis of amyotrophic lateral sclerosis | Q71894900 | ||
Toward an understanding of the role of glutamate in experimental parkinsonism: Agonist‐sensitive sites in the basal ganglia | Q72100592 | ||
Decrease in Cu/Zn- and Mn-superoxide dismutase activities in brain and spinal cord of patients with amyotrophic lateral sclerosis | Q72116629 | ||
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors | Q72209261 | ||
Parkinson's disease: a test of the multifactorial etiologic hypothesis | Q72391740 | ||
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis | Q72529952 | ||
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis | Q72621641 | ||
Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis | Q72663413 | ||
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group | Q72759362 | ||
P433 | issue | 4 | |
P921 | main subject | neurodegeneration | Q1755122 |
deleterious network hypothesis | Q108305420 | ||
P304 | page(s) | 307-313 | |
P577 | publication date | 1996-10-01 | |
P1433 | published in | Medical Hypotheses | Q5558534 |
P1476 | title | A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis. | |
P478 | volume | 47 |
Q44179098 | Chemotherapeutically induced deletion of expanded triplet repeats |
Q73168807 | Deleterious network hypothesis of aging |
Q74817365 | Deleterious network hypothesis of apoptosis |
Q63341579 | Evaluation of free radical production, mitochondrial membrane potential and cytoplasmic calcium in mammalian neurons by flow cytometry |
Q83728053 | Huntington's Disease |
Q38151200 | Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms |
Q89880514 | Multimodal Abnormalities of Brain Structure and Function in Major Depressive Disorder: A Meta-Analysis of Neuroimaging Studies |
Q37015565 | NAD+ and NADH in neuronal death |
Q36090617 | Oxidative stress and NAD+ in ischemic brain injury: current advances and future perspectives |
Q23920334 | Potential occupational risks for neurodegenerative diseases |
Q35120158 | Serum containing Tongqiaohuoxue decoction suppresses glutamate-induced PC12 cell injury |
Q44924668 | Toxic effect of chloromycetin on the ultrastructures of the motor neurons of the Chinese tree shrew (Tupaia belangeri). |
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