| scholarly article | Q13442814 |
| P2093 | author name string | Antonio Valencia | |
| Ellen Sapp | |||
| Jonathan Alexander | |||
| Kathryn Chase | |||
| Kimberly B Kegel | |||
| Marian DiFiglia | |||
| Neil Aronin | |||
| Xueyi Li | |||
| Patrick B Reeves | |||
| P2860 | cites work | Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons | Q24317574 |
| Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function | Q24646918 | ||
| The challenge of lipid rafts | Q24652892 | ||
| 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts | Q24679777 | ||
| A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
| Lipid rafts and signal transduction | Q28131735 | ||
| Expression of full-length polyglutamine-expanded Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells | Q28208803 | ||
| LTP inhibits LTD in the hippocampus via regulation of GSK3beta | Q28290606 | ||
| Flotillin-1 in the substantia nigra of the Parkinson brain and a predominant localization in catecholaminergic nerves in the rat brain | Q28293426 | ||
| Neurological abnormalities in a knock-in mouse model of Huntington's disease | Q28508179 | ||
| Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons | Q28565001 | ||
| Recruitment of active glycogen synthase kinase-3 into neuronal lipid rafts | Q28567543 | ||
| Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity | Q28568803 | ||
| Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats | Q28587110 | ||
| The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling | Q29620489 | ||
| Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice | Q30437914 | ||
| Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus | Q30486228 | ||
| N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking | Q30486372 | ||
| Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease | Q33231356 | ||
| Are there multiple pathways in the pathogenesis of Huntington's disease? | Q33703905 | ||
| Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover | Q34067259 | ||
| Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study | Q34099067 | ||
| Growth factor receptors, lipid rafts and caveolae: an evolving story | Q36160385 | ||
| Are cognitive changes the first symptoms of Huntington's disease? A study of gene carriers | Q36317837 | ||
| Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles | Q36639079 | ||
| Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats | Q37142702 | ||
| Line tension at lipid phase boundaries regulates formation of membrane vesicles in living cells | Q39967400 | ||
| Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease | Q40031554 | ||
| GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis | Q40100057 | ||
| Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signalling | Q40175298 | ||
| Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3beta signaling | Q40209568 | ||
| Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences | Q40231756 | ||
| Ligand-independent activation of the EGFR by lipid raft disruption | Q40321066 | ||
| Huntingtin associates with acidic phospholipids at the plasma membrane | Q40387540 | ||
| Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene | Q40393169 | ||
| Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis. | Q40469664 | ||
| Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release | Q40551652 | ||
| The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly | Q40591985 | ||
| Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells | Q40895692 | ||
| Microdomains of GPI-anchored proteins in living cells revealed by crosslinking | Q41011350 | ||
| An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. | Q41810461 | ||
| Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment | Q41871412 | ||
| Flotillas of lipid rafts in transit amplifying cell-like keratinocytes | Q42446273 | ||
| Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt. | Q42446820 | ||
| Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum | Q42448748 | ||
| Regulation of AMPA receptor localization in lipid rafts | Q42539034 | ||
| Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction | Q42806144 | ||
| Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses | Q44092340 | ||
| Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. | Q44101117 | ||
| AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3‐induced T cell signaling | Q44411064 | ||
| Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells | Q44605170 | ||
| Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains | Q45192504 | ||
| Loss of cannabinoid receptors in the substantia nigra in Huntington's disease. | Q45290294 | ||
| Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial | Q45297817 | ||
| Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease. | Q45298923 | ||
| Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation | Q45306368 | ||
| Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane | Q46272996 | ||
| A function of huntingtin in guanine nucleotide exchange on Rab11. | Q46322702 | ||
| Spatial memory formation induces recruitment of NMDA receptor and PSD-95 to synaptic lipid rafts. | Q46432024 | ||
| Simvastatin reduces the association of NMDA receptors to lipid rafts: a cholesterol-mediated effect in neuroprotection. | Q46716166 | ||
| Caspase-dependent apoptosis induced by calcineurin inhibitors was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical cells | Q48339440 | ||
| Glycogen synthase kinase-3beta activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells | Q48342992 | ||
| GPI-anchored proteins are organized in submicron domains at the cell surface. | Q52531693 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | membrane raft | Q424178 |
| Huntington's disease | Q190564 | ||
| P304 | page(s) | 179-190 | |
| P577 | publication date | 2010-01-01 | |
| P1433 | published in | Journal of Neuroscience Research | Q6295654 |
| P1476 | title | Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease | |
| P478 | volume | 88 |
| Q37142133 | Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding. |
| Q28742804 | Amyloid oligomer neurotoxicity, calcium dysregulation, and lipid rafts |
| Q97532440 | Brain sterol flux mediated by cytochrome P450 46A1 affects membrane properties and membrane-dependent processes |
| Q37842745 | Cannabinoid receptor signalling in neurodegenerative diseases: a potential role for membrane fluidity disturbance |
| Q37926912 | Cholesterol metabolism in Huntington disease |
| Q90436552 | Co-morbidities of HIV infection: role of Nef-induced impairment of cholesterol metabolism and lipid raft functionality |
| Q37947984 | Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development. |
| Q44770443 | DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes |
| Q45288661 | Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease. |
| Q26783348 | Dopamine Receptors and Neurodegeneration |
| Q36854994 | Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice. |
| Q36626877 | Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease |
| Q51737507 | Estrogen Interactions With Lipid Rafts Related to Neuroprotection. Impact of Brain Ageing and Menopause. |
| Q27026606 | Exosomes: mediators of neurodegeneration, neuroprotection and therapeutics |
| Q36002017 | GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions |
| Q35056067 | HD CAG-correlated gene expression changes support a simple dominant gain of function |
| Q36482299 | Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. |
| Q41881745 | Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors |
| Q36090810 | Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway |
| Q39176432 | Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance |
| Q38173298 | Lipid rafts in neurodegeneration and neuroprotection |
| Q39014909 | Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain. |
| Q45290192 | Mass Spectrometry Analysis of Wild-Type and Knock-in Q140/Q140 Huntington's Disease Mouse Brains Reveals Changes in Glycerophospholipids Including Alterations in Phosphatidic Acid and Lyso-Phosphatidic Acid |
| Q28397548 | Mitochondrial lipids in neurodegeneration |
| Q34663489 | Multivesicular bodies in neurons: distribution, protein content, and trafficking functions |
| Q35921703 | Native mutant huntingtin in human brain: evidence for prevalence of full-length monomer |
| Q35577571 | PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. |
| Q37212391 | Partial Amelioration of Peripheral and Central Symptoms of Huntington's Disease via Modulation of Lipid Metabolism |
| Q38218040 | Pathogenic role of ganglioside metabolism in neurodegenerative diseases |
| Q38107677 | Pharmacological protein targets in polyglutamine diseases: mutant polypeptides and their interactors |
| Q64236137 | Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease |
| Q38344567 | Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis. |
| Q64231794 | Roles of PI3K/AKT/GSK3 Pathway Involved in Psychiatric Illnesses |
| Q49331880 | Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes |
| Q38568655 | Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulation |
| Q47251076 | The 17-residue-long N terminus in huntingtin controls step-wise aggregation in solution and on membranes via different mechanisms |
| Q26745558 | The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence |
| Q28244138 | The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS |
| Q36873629 | The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin |
| Q59133543 | Ubiquitin C-terminal Hydrolase L1 Regulates Lipid Raft-dependent Endocytosis |
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