Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease

scientific article published in September 1999

Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/BRAIN/122.9.1667
P698PubMed publication ID10468506
P5875ResearchGate publication ID277511651

P50authorJason BrandtQ43079703
P2093author name stringHarris GJ
Bedi A
Lewis RF
Schmidt E
Codori AM
P2860cites workCerebral blood flow velocity decreases during cognitive stimulation in Huntington's diseaseQ45296983
Positron emission tomography in the early diagnosis of Huntington's diseaseQ45297664
PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional declineQ45297931
Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's diseaseQ45298088
Normal caudate glucose metabolism in persons at risk for Huntington's diseaseQ45298212
The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's diseaseQ45298502
Positron emission tomographic scan investigations of Huntington's disease: cerebral metabolic correlates of cognitive functionQ45299001
Diagnostic value of CT in patients with Huntington's chorea and their offspringQ45303963
Cerebral metabolism and atrophy in huntington's disease determined by18FDG and computed tomographic scanQ45304491
Computed Tomographic, Neurologic, and Neuropsychological Correlates of Huntington'S DiseaseQ45304617
Reduced striatal glucose consumption and prolonged reaction time are early features in Huntington's diseaseQ45305415
MRI-guided region of interest placement on emission computed tomogramsQ48306253
Laboratory Guidelines for Huntington Disease Genetic TestingQ57629033
“Mini-mental state”Q25938989
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.Q27860836
Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and CortexQ29391304
Reduced regional cerebral blood flow in Huntington's disease studied by SPECT.Q33592003
Neuronal distribution in the putamen in Huntington's diseaseQ33621030
Neuropsychological and neuroradiological correlates in Huntington's diseaseQ33630738
Bicaudate index in computerized tomography of Huntington disease and cerebral atrophyQ39867392
A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's diseaseQ41175762
Cortical glucose metabolism in Huntington's diseaseQ45111537
Striatal glucose consumption in chorea-free subjects at risk of Huntington's diseaseQ45289936
Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons.Q45290072
Comparison of somatosensory evoked potentials with striatal glucose consumption measured by positron emission tomography in the early diagnosis of Huntington's diseaseQ45290976
Trial of d-alpha-tocopherol in Huntington's diseaseQ45291405
Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease.Q45291612
Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's diseaseQ45291881
Psychiatric, genetic, and positron emission tomographic evaluation of persons at risk for Huntington's diseaseQ45291899
Cerebral structure on MRI, part II: Specific changes in Alzheimer's and Huntington's diseasesQ45292929
Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's diseaseQ45293368
Basal ganglia volume and proximity to onset in presymptomatic Huntington diseaseQ45293561
Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease.Q45294680
Clinical-pathologic correlation in Huntington's disease: a neuropsychological and computed tomography studyQ45295565
Brain atrophy in Huntington's disease. A CT-scan studyQ45295633
Cerebral glucose consumption measured by PET in patients with and without psychiatric symptoms of Huntington's diseaseQ45295880
Atrophy of corpus striatum in normal male at risk of Huntington's choreaQ45296618
P407language of work or nameEnglishQ1860
P921main subjectHuntington's diseaseQ190564
P304page(s)1667-1678
P577publication date1999-09-01
P1433published inBrainQ897386
P1476titleReduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease
P478volume122 ( Pt 9)

Reverse relations

cites work (P2860)
Q33908988A structural MRI study of human brain development from birth to 2 years.
Q45305568Aberrant astrocytes impair vascular reactivity in Huntington disease
Q34917383Abnormal error-related antisaccade activation in premanifest and early manifest Huntington disease
Q39298090Admixing of MPTP-Resistant and Susceptible Mice Strains Augments Nigrostriatal Neuronal Correlates to Resist MPTP-Induced Neurodegeneration
Q40008936Basal ganglia volume and clinical correlates in 'preclinical' Huntington's disease
Q45305215Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
Q37949813Cerebrovascular disorders: molecular insights and therapeutic opportunities
Q36480706Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Q37207535Complex relationships between cerebral blood flow and brain atrophy in early Huntington's disease.
Q36711087Consistent neurodegeneration and its association with clinical progression in Huntington's disease: a coordinate-based meta-analysis
Q33861321Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study
Q36941187Detection of Huntington's disease decades before diagnosis: the Predict-HD study
Q33907629Development of biomarkers for Huntington's disease
Q44517166Difficulty modifying a sustained motor response in prodromal Huntington's disease
Q37179508Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease.
Q45292699Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease
Q35037327Early atrophy of pallidum and accumbens nucleus in Huntington's disease
Q37580232Early defect of transforming growth factor β1 formation in Huntington's disease.
Q37325474Elevated arteriolar cerebral blood volume in prodromal Huntington's disease
Q88805262Genetic load determines atrophy in hand cortico-striatal pathways in presymptomatic Huntington's disease
Q33405399Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice
Q40154686Heritability and genome-wide associations studies of cerebral blood flow in the general population
Q36685619History of Neural Stem Cell Research and Its Clinical Application
Q35918287Human neural stem cells genetically modified for brain repair in neurological disorders
Q45288836Implicit contextual learning in prodromal and early stage Huntington's disease patients.
Q35954594Language deficits in pre-symptomatic Huntington's disease: evidence from Hungarian.
Q41842696Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration
Q30660816Magnetic resonance imaging and magnetic resonance spectroscopy in dementias
Q33437923Magnetic resonance imaging of Huntington's disease: preparing for clinical trials
Q35262146Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington's disease
Q45303170Modeling longitudinal change in motor and cognitive processing speed in presymptomatic Huntington's disease
Q33743709Motor-Language Coupling in Huntington's Disease Families
Q38079295Neural stem cell-based treatment for neurodegenerative diseases
Q34474382Neurocognitive signs in prodromal Huntington disease
Q36314026Neuroimaging and human genetics
Q29615839Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Q38395042Non-Verbal and Verbal Fluency in Prodromal Huntington's Disease
Q64912813Novel targets for Huntington's disease: future prospects.
Q36900689Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression
Q38385717Progress in Huntington's disease: the search for markers of disease onset and progression
Q35487438Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study.
Q38191477Prospects for neuroprotective therapies in prodromal Huntington's disease
Q36902073Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease.
Q45304803Reduced striato-cortical and inhibitory transcallosal connectivity in the motor circuit of Huntington's disease patients.
Q41169433Scanning Patterns of Faces do not Explain Impaired Emotion Recognition in Huntington Disease: Evidence for a High Level Mechanism
Q33606063Seeking brain biomarkers for preventive therapy in Huntington disease.
Q36510210Seminar on choreas
Q45305995Sensation of effort is altered in Huntington's disease
Q30485428Striatal degeneration impairs language learning: evidence from Huntington's disease.
Q36269123Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease
Q35612769Striatal volume contributes to the prediction of onset of Huntington disease in incident cases
Q36025447Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
Q38663086The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers
Q36462035The search for cerebral biomarkers of Huntington's disease: a review of genetic models of age at onset prediction
Q35479486Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study.
Q45305904fMRI detection of early neural dysfunction in preclinical Huntington's disease

Search more.