Wikidata entity: Q45314353
| P2888 | exact match | Url | Reactome | Constitutive Signaling by EGFRvIII | ??? |
| P703 | found in taxon | ... | Q15978631 (Homo sapiens) | Homo sapiens |
| P527 | has part(s) | ... | Q50288621 (HSP90 is inactivated by binding to benzaquinoid ansamycins) | HSP90 is inactivated by binding to benzaquinoid ansamycins |
| P527 | has part(s) | ... | Q50288625 (EGFRvIII mutant binds chaperone proteins HSP90 and CDC37.) | EGFRvIII mutant binds chaperone proteins HSP90 and CDC37. |
| P527 | has part(s) | ... | Q50288627 (EGFRvIII cancer variant does not bind EGF ligand) | EGFRvIII cancer variant does not bind EGF ligand |
| P527 | has part(s) | ... | Q50288631 (Ligand-independent dimerization of EGFRvIII mutant) | Ligand-independent dimerization of EGFRvIII mutant |
| P527 | has part(s) | ... | Q50288633 (Trans-autophosphorylation of EGFRvIII mutant dimers) | Trans-autophosphorylation of EGFRvIII mutant dimers |
| P527 | has part(s) | ... | Q50288634 (Binding of GRB2:SOS1 complex to phosphorylated EGFRvIII) | Binding of GRB2:SOS1 complex to phosphorylated EGFRvIII |
| P527 | has part(s) | ... | Q50288635 (SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII)) | SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) |
| P527 | has part(s) | ... | Q50288636 (Binding of SHC1 to p-5Y-EGFRvIII) | Binding of SHC1 to p-5Y-EGFRvIII |
| P527 | has part(s) | ... | Q50288638 (Phosphorylation of SHC1 by p-5Y-EGFRvIII) | Phosphorylation of SHC1 by p-5Y-EGFRvIII |
| P527 | has part(s) | ... | Q50288639 (Phosphorylated SHC1 in complex with p-5Y-EGFRvIII recruits GRB2:SOS1 complex) | Phosphorylated SHC1 in complex with p-5Y-EGFRvIII recruits GRB2:SOS1 complex |
| P527 | has part(s) | ... | Q50288640 (SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII)) | SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) |
| P527 | has part(s) | ... | Q50288641 (Binding of GRB2:GAB1 complex to p-EGFRvIII mutant) | Binding of GRB2:GAB1 complex to p-EGFRvIII mutant |
| P527 | has part(s) | ... | Q50288645 (Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII) | Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII |
| P527 | has part(s) | ... | Q50288646 (Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII) | Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII |
| P527 | has part(s) | ... | Q50288647 (PLC-gamma 1 binds to p-EGFRvIII mutant) | PLC-gamma 1 binds to p-EGFRvIII mutant |
| P527 | has part(s) | ... | Q50288648 (Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant) | Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant |
| P527 | has part(s) | ... | Q50288649 (Dissociation of phosphorylated PLC-gamma 1 from p-EGFRvIII mutant) | Dissociation of phosphorylated PLC-gamma 1 from p-EGFRvIII mutant |
| P527 | has part(s) | ... | Q50288650 (EGFRvIII does not bind CBL) | EGFRvIII does not bind CBL |
| P31 | instance of | ... | Q4915012 (biological pathway) | biological pathway |
| P361 | part of | ... | Q45314352 (Signaling by EGFRvIII in Cancer) | Signaling by EGFRvIII in Cancer |
| P3937 | Reactome ID | R-HSA-5637810 |
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log id: 6102115