biological pathway | Q4915012 |
P2888 | exact match | https://identifiers.org/reactome:R-HSA-844456 |
P3937 | Reactome ID | R-HSA-844456 |
P2860 | cites work | The inflammasomes | Q24304087 |
The NLRP3 inflammasome: a sensor of immune danger signals | Q37379011 | ||
P703 | found in taxon | Homo sapiens | Q15978631 |
P527 | has part(s) | ATP binds to P2X7 | Q50291962 |
P2X7 forms oligomeric non-selective cation channels | Q50291963 | ||
P2X7 mediates loss of intracellular K+ | Q50291964 | ||
P2X7 mediates membrane pores that include pannexin-1 | Q50291965 | ||
SGT1 binds HSP90 | Q50291966 | ||
SGT1:HSP90 binds inactive NLRP3 | Q50291967 | ||
TXNIP binds reduced thioredoxin | Q50291968 | ||
ROS oxidize thioredoxin | Q50291970 | ||
TXNIP is released from oxidized thioredoxin | Q50291971 | ||
TXNIP binds NLRP3 | Q50291972 | ||
NLRP3 activation by small molecules | Q50291977 | ||
NLRP3 activation by elicitor proteins | Q50291979 | ||
NLRP3 oligomerizes via NACHT domains | Q50291980 | ||
NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction | Q50291982 | ||
PYCARD recruits procaspase-1 via CARD | Q50291983 | ||
PSTPIP1 binds Pyrin | Q50291985 | ||
Pyrin binds ASC | Q50291987 | ||
Expression of NLRP3 gene | Q56858965 | ||
P361 | part of | Inflammasomes | Q45317048 |
Q50291962 | ATP binds to P2X7 |
Q56858965 | Expression of NLRP3 gene |
Q50291979 | NLRP3 activation by elicitor proteins |
Q50291977 | NLRP3 activation by small molecules |
Q50291980 | NLRP3 oligomerizes via NACHT domains |
Q50291982 | NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction |
Q50291963 | P2X7 forms oligomeric non-selective cation channels |
Q50291964 | P2X7 mediates loss of intracellular K+ |
Q50291965 | P2X7 mediates membrane pores that include pannexin-1 |
Q50291985 | PSTPIP1 binds Pyrin |
Q50291983 | PYCARD recruits procaspase-1 via CARD |
Q50291987 | Pyrin binds ASC |
Q50291970 | ROS oxidize thioredoxin |
Q50291966 | SGT1 binds HSP90 |
Q50291967 | SGT1:HSP90 binds inactive NLRP3 |
Q50291972 | TXNIP binds NLRP3 |
Q50291968 | TXNIP binds reduced thioredoxin |
Q50291971 | TXNIP is released from oxidized thioredoxin |
Q45317048 | Inflammasomes | has part(s) | P527 |
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