Regulation of necroptotic cell death

instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5675482)

Wikidata entity: Q45317931



P2860 cites work ... Q24311676 (???) ???
P2860 cites work ... Q24607621 (???) ???
P2860 cites work ... Q28284721 (???) ???
P2860 cites work ... Q38330819 (???) ???
P2860 cites work ... Q39644966 (???) ???
P2860 cites work ... Q39729607 (???) ???
P2860 cites work ... Q55392555 (???) ???
P2888 exact match Url Reactome | Regulation of necroptotic cell death ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q45317933 (CASP8 activity is inhibited) CASP8 activity is inhibited
P527 has part(s) ... Q50297442 (BIRC2/3 (cIAP1/2) is autoubiquitinated) BIRC2/3 (cIAP1/2) is autoubiquitinated
P527 has part(s) ... Q50297443 (RIPK1 is cleaved by CASP8) RIPK1 is cleaved by CASP8
P527 has part(s) ... Q101226931 (RIPK3 is cleaved by CASP8) RIPK3 is cleaved by CASP8
P527 has part(s) ... Q101226934 (PELI1 binds activated RIPK1:RIPK3) PELI1 binds activated RIPK1:RIPK3
P527 has part(s) ... Q101226939 (PELI1 ubiquitinates RIPK3 at K363) PELI1 ubiquitinates RIPK3 at K363
P527 has part(s) ... Q101226943 (ATP binds MLKL) ATP binds MLKL
P527 has part(s) ... Q101226948 (MLKL binds IP4, IP5 and IP6) MLKL binds IP4, IP5 and IP6
P527 has part(s) ... Q101226952 (O-GlcNAcylation of RIPK3 (TLR4 signaling)) O-GlcNAcylation of RIPK3 (TLR4 signaling)
P527 has part(s) ... Q101226955 (RIPK3 binds HSP90:CDC37) RIPK3 binds HSP90:CDC37
P527 has part(s) ... Q101226965 (MLKL binds HSP90:CDC37) MLKL binds HSP90:CDC37
P527 has part(s) ... Q101226969 (MLKL binds FLOT1, FLOT2) MLKL binds FLOT1, FLOT2
P527 has part(s) ... Q101226974 (MLKL binds PDCD6IP and SDCBP) MLKL binds PDCD6IP and SDCBP
P527 has part(s) ... Q101226979 (RIPK3 binds STUB1) RIPK3 binds STUB1
P527 has part(s) ... Q101226986 (STUB1 ubiquitinates RIPK3 at K55, K363) STUB1 ubiquitinates RIPK3 at K55, K363
P527 has part(s) ... Q101227000 (Small molecule inhibitor binds RIPK1, RIPK3) Small molecule inhibitor binds RIPK1, RIPK3
P31 instance of ... Q4915012 (biological pathway) biological pathway
P31 instance of ... Q21111700 (regulation of necroptotic process) regulation of necroptotic process
P361 part of ... Q45317929 (RIPK1-mediated regulated necrosis) RIPK1-mediated regulated necrosis

External Ids
P3937Reactome IDR-HSA-5675482

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log id: 5905412