NRAGE signals death through JNK

instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-193648)

Wikidata entity: Q45318016



P2860 cites work ... Q34154153 (???) ???
P2888 exact match Url Reactome | NRAGE signals death through JNK ???
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q50297683 (NGF:p75NTR complex binds to NRAGE) NGF:p75NTR complex binds to NRAGE
P527 has part(s) ... Q50297684 (NRAGE sequesters CHE1 in the cytoplasm) NRAGE sequesters CHE1 in the cytoplasm
P527 has part(s) ... Q50297685 (NRAGE activates JNK) NRAGE activates JNK
P527 has part(s) ... Q50297686 (p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor) p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor
P527 has part(s) ... Q50297687 (GTP-bound RAC contributes to JNK activation) GTP-bound RAC contributes to JNK activation
P527 has part(s) ... Q50297688 (JNK phosphorylates BIM, BAD and other targets) JNK phosphorylates BIM, BAD and other targets
P527 has part(s) ... Q50297689 (Active JNK moves to the nucleus and phosphorylates different transcription factors) Active JNK moves to the nucleus and phosphorylates different transcription factors
P31 instance of ... Q4915012 (biological pathway) biological pathway
P31 instance of ... Q14818063 (positive regulation of apoptotic process) positive regulation of apoptotic process
P361 part of ... Q45318014 (Cell death signalling via NRAGE, NRIF and NADE) Cell death signalling via NRAGE, NRIF and NADE

External Ids
P3937Reactome IDR-HSA-193648

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log id: 7382674