Insulin receptor signalling cascade

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-74751)

Insulin receptor signalling cascade is …
instance of (P31):
biological pathwayQ4915012

External links are
P2888exact matchhttps://identifiers.org/reactome:R-HSA-74751
P3937Reactome IDR-HSA-74751

P2860cites workInsulin signallingQ28611467
Phosphoinositide 3-kinase: the key switch mechanism in insulin signallingQ42991205
P703found in taxonHomo sapiensQ15978631
P527has part(s)IRS activationQ45318060
IRS-mediated signallingQ45318061
Signal attenuationQ45318069
GRB2-1 binds SOS1Q50297463
Binding of SHC1 to insulin receptorQ50297793
Phosphorylation of SHC1Q50297794
Dissociation of p-Y427-SHC1 from insulin receptorQ50297795
GRB2-1:SOS1 binds p-Y427-SHC1Q50297796
GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RASQ50297797
P361part ofSignaling by Insulin receptorQ45318056

Reverse relations

part of (P361)
Q50297793Binding of SHC1 to insulin receptor
Q50297795Dissociation of p-Y427-SHC1 from insulin receptor
Q50297463GRB2-1 binds SOS1
Q50297796GRB2-1:SOS1 binds p-Y427-SHC1
Q50297797GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS
Q45318060IRS activation
Q45318061IRS-mediated signalling
Q50297794Phosphorylation of SHC1
Q45318069Signal attenuation

Q45318056Signaling by Insulin receptorhas part(s)P527

Search more.