Olfactory Signaling Pathway

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-381753)

Olfactory Signaling Pathway is …
instance of (P31):
biological pathwayQ4915012

External links are
P2888exact matchhttps://identifiers.org/reactome:R-HSA-381753
P3937Reactome IDR-HSA-381753

P2860cites workGenetic elucidation of human hyperosmia to isovaleric acidQ21092752
Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarrayQ21184121
Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER networkQ24301595
The human olfactory receptor gene familyQ24312045
RTP family members induce functional expression of mammalian odorant receptorsQ24315887
Loss of association of REEP2 with membranes leads to hereditary spastic paraplegiaQ24317205
Members of RTP and REEP gene families influence functional bitter taste receptor expressionQ24337758
Expression of members of the putative olfactory receptor gene family in mammalian germ cellsQ24338448
Better smelling through genetics: mammalian odor perceptionQ24652727
A class of membrane proteins shaping the tubular endoplasmic reticulumQ27940194
Genetic variation in a human odorant receptor alters odour perceptionQ28249046
A novel multigene family may encode odorant receptors: a molecular basis for odor recognitionQ28276183
REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacityQ28507125
Mice deficient in G(olf) are anosmicQ28512241
A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMPQ28565745
Identification of a specialized adenylyl cyclase that may mediate odorant detectionQ28581625
ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplificationQ28587956
Human olfactory receptor responses to odorants.Q35632512
Heterotrimeric G-proteins: a short historyQ36364445
Heterotrimeric G protein activation by G-protein-coupled receptorsQ37017125
Monogenic and Monoallelic Expression of Odorant ReceptorsQ38944569
Olfactory receptor trafficking involves conserved regulatory stepsQ40845252
Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, GolfQ41743997
Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptorsQ45345834
Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein.Q45345836
P703found in taxonHomo sapiensQ15978631
P527has part(s)ADCY3:GNAL:GTP converts ATP to cAMPQ112996689
cAMP binds the olfactory CNG channelQ112996690
odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13Q112996692
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1Q112996723
ANO2 dimer binds Ca2+Q112996725
ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular regionQ112996727
cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosolQ112996728
GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13Q112996734
GNAL:GTP (G alpha-olf) binds ADCY3Q112996736
Expression and translocation of olfactory receptorsQ113001263
P361part ofSensory PerceptionQ106520219