MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction

scientific article published on 18 October 2017

MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M117.805937
P932PMC publication ID5766960
P698PubMed publication ID29046356

P2093author name stringLi Zhou
Jun Wang
Mengji Lu
Ying Zhu
Qian Li
Yong Lin
Xueyuan Chen
Xueyu Wang
Haisheng Yu
Shi Liu
Nanfang Peng
Zhongying Cao
Chengliang Zhu
Mengqi Li
Yinglong She
P2860cites workType I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factorsQ24303448
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Engineering H5N1 avian influenza viruses to study human adaptationQ28386710
A dicer-independent miRNA biogenesis pathway that requires Ago catalysisQ28508177
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IKKβ is an IRF5 kinase that instigates inflammationQ34709052
Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infectionQ35165316
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Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppressionQ35652186
Attenuation of Cardiac Dysfunction in Polymicrobial Sepsis by MicroRNA-146a Is Mediated via Targeting of IRAK1 and TRAF6 ExpressionQ35815694
Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responsesQ35889350
Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B.Q35914443
The cytokine storm of severe influenza and development of immunomodulatory therapyQ36459143
The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1Q36481240
Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoterQ36949730
Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5Q37510166
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infectionQ37640926
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infectionQ38525056
Generation of influenza A viruses as live but replication-incompetent virus vaccinesQ38726947
Mir-302c mediates influenza A virus-induced IFNβ expression by targeting NF-κB inducing kinaseQ38817129
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Regulatory roles of c-jun in H5N1 influenza virus replication and host inflammation.Q39000336
Modulation of interferon regulatory factor 5 activities by the Kaposi sarcoma-associated herpesvirus-encoded viral interferon regulatory factor 3 contributes to immune evasion and lytic inductionQ39623528
Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptomeQ39794190
Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitinationQ39934389
NF-kappaB signaling differentially regulates influenza virus RNA synthesisQ39950905
Development of a more efficient hepatitis B virus vaccine by targeting hepatitis B virus preS to dendritic cellsQ40189385
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Inducible Major Vault Protein Plays a Pivotal Role in Double-Stranded RNA- or Virus-Induced Proinflammatory Response.Q40806217
TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling PathwayQ41153717
Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling LoopQ41561057
Human hepatitis B virus surface and e antigens inhibit major vault protein signaling in interferon induction pathwaysQ41613683
Major vault protein: a virus-induced host factor against viral replication through the induction of type-I interferonQ42977583
The advent of the cytokine stormQ47834672
Genistein Protects Against Ox-LDL-Induced Inflammation Through MicroRNA-155/SOCS1-Mediated Repression of NF-ĸB Signaling Pathway in HUVECs.Q50976249
Sepsis: calming the cytokine stormQ84135047
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responsesQ84174846
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
cytokine stormQ1076369
P577publication date2017-10-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleMicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction

Reverse relations

cites work (P2860)
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Q89790331IRF5 promotes influenza-induced inflammatory responses in human iPSC-derived myeloid cells and murine models
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Q96135741O-GlcNAc transferase promotes influenza A virus-induced cytokine storm by targeting interferon regulatory factor-5
Q59356513Potential Role of MicroRNAs in the Regulation of Antiviral Responses to Influenza Infection
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Q98568802miR-1975 serves as an indicator of clinical severity upon influenza infection

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