Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?

scientific article published on 10 July 2012

Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1159/000338048
P698PubMed publication ID22796962

P50authorSusanne PetriQ67224132
Reinhard DenglerQ67224134
Sonja KörnerQ90773661
Nadine ThauQ114410642
Sebastian BöseltQ114410649
Klaus Jan RathQ114410651
P2860cites workDistribution of histone deacetylases 1-11 in the rat brainQ40225359
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stressQ42811705
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neuronsQ42914852
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Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis miceQ46526611
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Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosisQ46805732
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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylaseQ24310456
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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanismsQ24597989
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Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulinQ28572741
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosisQ28583941
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Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activityQ33396651
An in vitro screening cascade to identify neuroprotective antioxidants in ALSQ33445432
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer diseaseQ33619317
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.Q34406809
Current hypotheses for the underlying biology of amyotrophic lateral sclerosisQ34936518
Sirtuins: the 'magnificent seven', function, metabolism and longevityQ36911415
Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.Q36967971
Paths of convergence: sirtuins in aging and neurodegenerationQ37133425
Therapeutic application of histone deacetylase inhibitors for central nervous system disordersQ37283454
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Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords--screening by molecular indexing and subsequent cDNA microarray analysisQ38361317
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motilityQ40003738
P433issue3
P921main subjectamyotrophic lateral sclerosisQ206901
neurotoxicityQ3338704
P304page(s)141-152
P577publication date2012-07-10
P1433published inNeurodegenerative DiseasesQ15764918
P1476titleDifferential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS?
P478volume11

Reverse relations

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