scholarly article | Q13442814 |
P356 | DOI | 10.1159/000338048 |
P698 | PubMed publication ID | 22796962 |
P50 | author | Susanne Petri | Q67224132 |
Reinhard Dengler | Q67224134 | ||
Sonja Körner | Q90773661 | ||
Nadine Thau | Q114410642 | ||
Sebastian Böselt | Q114410649 | ||
Klaus Jan Rath | Q114410651 | ||
P2860 | cites work | Distribution of histone deacetylases 1-11 in the rat brain | Q40225359 |
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress | Q42811705 | ||
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons | Q42914852 | ||
Distribution of GABAA receptor subunit mRNAs in rat lumbar spinal cord | Q43968835 | ||
Distribution of GABAAReceptor mRNA in the Motor Cortex of ALS Patients | Q44629514 | ||
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice | Q46526611 | ||
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1. | Q46656918 | ||
Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis | Q46805732 | ||
Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis | Q48199277 | ||
Amyotrophic lateral sclerosis | Q59219368 | ||
Negative control of p53 by Sir2alpha promotes cell survival under stress | Q24291828 | ||
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase | Q24297207 | ||
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle | Q24299947 | ||
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase | Q24310456 | ||
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins | Q24312912 | ||
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy | Q24316492 | ||
Sir2 mediates longevity in the fly through a pathway related to calorie restriction | Q24560016 | ||
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms | Q24597989 | ||
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 | Q28237795 | ||
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis | Q28279273 | ||
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease | Q28307422 | ||
Microtubule deacetylases, SirT2 and HDAC6, in the nervous system | Q28510189 | ||
Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1 | Q28512371 | ||
Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin | Q28572741 | ||
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis | Q28583941 | ||
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice | Q29619786 | ||
Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity | Q33396651 | ||
An in vitro screening cascade to identify neuroprotective antioxidants in ALS | Q33445432 | ||
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease | Q33619317 | ||
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. | Q34406809 | ||
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis | Q34936518 | ||
Sirtuins: the 'magnificent seven', function, metabolism and longevity | Q36911415 | ||
Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. | Q36967971 | ||
Paths of convergence: sirtuins in aging and neurodegeneration | Q37133425 | ||
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders | Q37283454 | ||
Histone deacetylation and motor neuron degeneration | Q37734508 | ||
Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords--screening by molecular indexing and subsequent cDNA microarray analysis | Q38361317 | ||
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility | Q40003738 | ||
P433 | issue | 3 | |
P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
neurotoxicity | Q3338704 | ||
P304 | page(s) | 141-152 | |
P577 | publication date | 2012-07-10 | |
P1433 | published in | Neurodegenerative Diseases | Q15764918 |
P1476 | title | Differential sirtuin expression patterns in amyotrophic lateral sclerosis (ALS) postmortem tissue: neuroprotective or neurotoxic properties of sirtuins in ALS? | |
P478 | volume | 11 |
Q89964362 | Antioxidant Alternatives in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review |
Q37352729 | Application of Targeted Mass Spectrometry for the Quantification of Sirtuins in the Central Nervous System. |
Q41475139 | Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders |
Q39036105 | Could Sirtuin Activities Modify ALS Onset and Progression? |
Q33659976 | Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model |
Q34730013 | Differential expression of sirtuin family members in the developing, adult, and aged rat brain. |
Q101237411 | Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases |
Q53348494 | Distinct patterns of sirtuin expression during progression of Alzheimer's disease. |
Q36012034 | Dysregulated expression of death, stress and mitochondrion related genes in the sciatic nerve of presymptomatic SOD1(G93A) mouse model of Amyotrophic Lateral Sclerosis |
Q39401700 | Emerging Roles of Sirtuins in Ischemic Stroke. |
Q89515362 | Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models |
Q52680237 | KATP Channel Expression and Genetic Polymorphisms Associated with Progression and Survival in Amyotrophic Lateral Sclerosis. |
Q39101800 | Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments |
Q90438582 | NAD+ in Brain Aging and Neurodegenerative Disorders |
Q100490695 | NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential |
Q47290734 | Neurodegenerative Disease Proteinopathies Are Connected to Distinct Histone Post-translational Modification Landscapes. |
Q28300666 | Neuroprotective Sirtuin ratio reversed by ApoE4 |
Q47105356 | Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism |
Q38186171 | SIRT1 in neurodevelopment and brain senescence |
Q38714676 | Sirt1 in cerebral ischemia |
Q38108128 | Sirtuin deacetylases in neurodegenerative diseases of aging |
Q34357662 | Sirtuins as therapeutic targets of ALS. |
Q58707338 | Sirtuins in Neuroendocrine Regulation and Neurological Diseases |
Q28255782 | The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia |
Q93014731 | Therapeutic alternative of the ketogenic Mediterranean diet to improve mitochondrial activity in Amyotrophic Lateral Sclerosis (ALS): A Comprehensive Review |
Q36179578 | Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways. |
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