Apoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells.

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Apoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/MOLECULES181012793
P932PMC publication ID6270536
P698PubMed publication ID24135937

P50authorTao YiQ57007152
Zhong-Zhen ZhaoQ88596224
Hubiao ChenQ37828912
P2093author name stringLan-Lan Fan
Yi-Na Tang
Min-Ting Lin
Jian-Ye Zhang
Xi-Cheng He
P2860cites workVandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport functionQ28475378
Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis.Q30877068
High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agentQ33321838
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenolsQ33864180
Activation of the PI3K/Akt pathway and chemotherapeutic resistanceQ35046899
Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoproteinQ36166672
Current status on marine products with reversal effect on cancer multidrug resistanceQ36395803
Vascular endothelial growth factor and its receptor as drug targets in hematological malignanciesQ36737772
Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate.Q37361981
Jolkinolide B from Euphorbia fischeriana Steud induces apoptosis in human leukemic U937 cells through PI3K/Akt and XIAP pathwaysQ37461369
ERK activation by thymosin-beta-4 (TB4) overexpression induces paclitaxel-resistanceQ38510908
Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.Q39194428
Vincristine induces cell cycle arrest and apoptosis in SH-SY5Y human neuroblastoma cellsQ39249038
Reversing ABCB1-mediated multi-drug resistance from within cells using translocating immune conjugatesQ39350070
FG020326 sensitized multidrug resistant cancer cells to docetaxel-mediated apoptosis via enhancement of caspases activation.Q39351284
Apatinib (YN968D1) enhances the efficacy of conventional chemotherapeutical drugs in side population cells and ABCB1-overexpressing leukemia cellsQ39418811
YHHU0895, a novel synthetic small-molecule microtubule-destabilizing agent, effectively overcomes P-glycoprotein-mediated tumor multidrug resistanceQ39461436
Reversal effects of traditional Chinese herbs on multidrug resistance in cancer cells.Q39489207
Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway.Q39557459
Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtionQ39594943
Reversal of P-glycoprotein-mediated multidrug resistance in vitro by milbemycin compounds in adriamycin-resistant human breast carcinoma (MCF-7/adr) cellsQ39676325
Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathwayQ39830252
Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cellsQ39914460
Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxolQ40036920
Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cellsQ40105094
Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cellsQ40582811
Alkaloids isolated from natural herbs as the anticancer agents.Q42324855
Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiationQ42504535
BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivoQ42513895
HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.Q44450066
Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibitionQ45815093
Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells.Q53483899
Lgf-YL-9 induces apoptosis in human epidermoid carcinoma KB cells and multidrug resistant KBv200 cells via reactive oxygen species-independent mitochondrial pathway.Q53592311
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmultiple drug resistanceQ643839
P304page(s)12793-12808
P577publication date2013-10-16
P1433published inMoleculesQ151332
P1476titleApoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells
P478volume18

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cites work (P2860)
Q36879500Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway
Q38860154Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro.
Q34056422Long noncoding RNA MRUL promotes ABCB1 expression in multidrug-resistant gastric cancer cell sublines
Q51735182Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris.
Q35481434Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance
Q46316359Structure Identification and In Vitro Anticancer Activity of Lathyrol-3-phenylacetate-5,15-diacetate
Q28543083Tetramethylpyrazine suppresses transient oxygen-glucose deprivation-induced connexin32 expression and cell apoptosis via the ERK1/2 and p38 MAPK pathway in cultured hippocampal neurons
Q47100562Tomentodione M sensitizes multidrug resistant cancer cells by decreasing P-glycoprotein via inhibition of p38 MAPK signaling
Q47216949Towards Comprehension of the ABCB1/P-Glycoprotein Role in Chronic Myeloid Leukemia

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