The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity

scientific article published in November 2006

The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1365-2249.2006.03177.X
P932PMC publication ID1942054
P698PubMed publication ID17034588
P5875ResearchGate publication ID6759922

P2093author name stringG Schuler
J Y Humrich
S Greiner
L Jenne
B Sauter
P Thuman
P2860cites workVIRUSES IN THE TREATMENT OF CANCERQ61819636
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Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditionsQ74179201
Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trialQ78367011
Viral oncolysis: increased immunogenicity of host cell antigen associated with influenza virusQ27483975
Tumour-cell invasion and migration: diversity and escape mechanismsQ29547894
Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3.Q30305548
Viral transport and the cytoskeletonQ34132795
Inverse association between melanoma and previous vaccinations against tuberculosis and smallpox: results of the FEBIM studyQ34149440
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Dendritic cells resurrect antigens from dead cells.Q34207623
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Overview analysis of adjuvant therapies for melanoma--a special reference to results from vaccinia melanoma oncolysate adjuvant therapy trialsQ34446288
The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxvirusesQ34469355
Tumor-specific shared antigenic peptides recognized by human T cellsQ35005926
Regulation of F-actin-dependent processes by the Abl family of tyrosine kinasesQ35140568
Proteolytic and non-proteolytic migration of tumour cells and leucocytesQ35572273
Future directions for the field of oncolytic virotherapy: a perspective on the use of vaccinia virusQ35842621
Oncolytic viral therapies - the clinical experienceQ36318202
Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.Q36368308
Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.Q36370290
Human T cell responses against melanomaQ36427328
Nonreplicating vaccinia vector efficiently expresses recombinant genesQ37299518
Elucidation of the molecular mechanism underlying tumor-selective replication of the oncolytic adenovirus mutant ONYX-015.Q40340116
A phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer.Q40621333
Phase I clinical trial of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen and the B7.1 co-stimulatory moleculeQ40840410
Poxvirus as a vector to transduce human dendritic cells for immunotherapy: abortive infection but reduced APC functionQ40850940
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues.Q40869541
Modified vaccinia virus Ankara for delivery of human tyrosinase as melanoma-associated antigen: induction of tyrosinase- and melanoma-specific human leukocyte antigen A*0201-restricted cytotoxic T cells in vitro and in vivoQ40923272
Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-alphaQ41046482
A clinical histologic, and immunologic study of a case of metastatic malignant melanoma undergoing spontaneous remissionQ42445664
Intradermal injection of Newcastle disease virus-modified autologous melanoma cell lysate and interleukin-2 for adjuvant treatment of melanoma patients with resectable stage III diseaseQ42673382
Dendritic cells containing apoptotic melanoma cells prime human CD8+ T cells for efficient tumor cell lysisQ43620127
Antigen loading of dendritic cells with whole tumor cell preparationsQ44473359
A multivariate analysis of prognostic factors for melanoma patients with lesions greater than or equal to 3.65 mm in thickness. The importance of revealing alternative Cox modelsQ44799666
A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).Q45529367
Rapid induction of specific cytotoxic T lymphocytes against melanoma-associated antigens by a recombinant vaccinia virus vector expressing multiple immunodominant epitopes and costimulatory molecules in vivoQ45733521
Immunotherapy of Malignant Melanoma With Vaccinia VirusQ45814892
T Helper 1 Cytokine mRNA Is Increased in Spontaneously Regressing Primary MelanomasQ60683103
P433issue2
P921main subjectdendritic cellQ506253
Vaccinia virusQ1986297
P304page(s)344-353
P577publication date2006-11-01
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleThe highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity
P478volume146

Reverse relations

cites work (P2860)
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